CXCL1/GRO alpha/KC/CINC-1 Protein 275-GR-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCXCL1/GRO alpha/KC/CINC-1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $261.00Supplier Page View Company Product Page
Catalog Number275-GR-010/CF
SpeciesHuman
Size10 ug (also 50 ug)
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Molecule NameCXCL1/GRO alpha/KC/CINC-1
NCBI Full Gene NameC-X-C motif chemokine ligand 1
NCBI Gene AliasesSCYB1, MGSA-a, GROa, NAP-3, FSP, GRO1, MGSA
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight7.9 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human CXCL1/GRO alpha Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 50 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysisNat CommunDecember 11, 2023Zülal Cibir, Jacqueline Hassel, Justin Sonneck, Lennart Kowitz, Alexander Beer, Andreas Kraus, Gabriel Hallekamp, Martin Rosenkranz, Pascal Raffelberg, Sven Olfen, et al.Sigma-Aldrich, Munich, Germany), 2 μl human recombinant CXCL1 (final concentration: 100 ng/ml; Cat. No.: 275-GR-010/CF, R&D Systems, Minneapolis, MN, USA), or 2 μl human recombinant CXCL8 (final concentration: 100 ng/ml;

(2) IL-1 Generated by Oral Squamous Cell Carcinoma Stimulates Tumor-Induced and RANKL-Induced Osteoclastogenesis: A Possible Mechanism of Bone Resorption Induced by the Infiltration of Oral Squamous Cell CarcinomaInternational journal of molecular sciencesDecember 30, 2022Fukawa Y, Kayamori K, Tsuchiya M, Ikeda T.

(3) ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasionJCI insightSeptember 22, 2022Gnosa SP, Puig Blasco L, Piotrowski KB, Freiberg ML, Savickas S, Madsen DH, Auf dem Keller U, Kronqvist P, Kveiborg M.

(4) On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine stormCell reportsMarch 8, 2022Conod A, Silvano M, Ruiz I Altaba A.

(5) Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic woundeLifeFebruary 3, 2022Roy R, Zayas J, Singh SK, Delgado K, Wood SJ, Mohamed MF, Frausto DM, Albalawi YA, Price TP, Estupinian R, et al.

(6) Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 SignalingCellsJanuary 3, 2021Kwon JH, Kim M, Um S, Lee HJ, Bae YK, Choi SJ, Hwang HH, Oh W, Jin HJ.

(7) Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinibBMC cancerJuly 13, 2020Bornemann L, Schuster M, Schmitz S, Sobczak C, Bessen C, Merz SF, Jöckel KH, Haverkamp T, Gunzer M, Göthert JR.Sigma-Aldrich, Munich, Germany), 2 μl human recombinant CXCL1 (final concentration: 100 ng/ml; Cat. No.: 275-GR-010/CF, R&D Systems, Minneapolis, MN, USA), or 2 μl human recombinant CXCL8 (final concentration: 100 ng/ml;

(8) Neutrophil recruitment to inflamed joints can occur without cellular primingJournal of leukocyte biologyJune 1, 2019Björkman L, Christenson K, Davidsson L, Mårtensson J, Amirbeagi F, Welin A, Forsman H, Karlsson A, Dahlgren C, Bylund J.

(9) Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanomaNature communicationsFebruary 9, 2018Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, et al.

(10) CXCL1 induces senescence of cancer-associated fibroblasts via autocrine loops in oral squamous cell carcinomaPloS oneJanuary 1, 2018Kim EK, Moon S, Kim DK, Zhang X, Kim J.

(11) Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetesJCI insightJuly 6, 2017Schludi B, Moin ASM, Montemurro C, Gurlo T, Matveyenko AV, Kirakossian D, Dawson DW, Dry SM, Butler PC, Butler AE.

(12) Senescent peritoneal mesothelium creates a niche for ovarian cancer metastasesCell death & diseaseDecember 29, 2016Mikuła-Pietrasik J, Uruski P, Sosińska P, Maksin K, Piotrowska-Kempisty H, Kucińska M, Murias M, Szubert S, Woźniak A, Szpurek D, et al.

(13) Early dissemination seeds metastasis in breast cancerNatureDecember 22, 2016Hosseini H, Obradović MMS, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, et al.

(14) P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathyCell researchJune 1, 2015Wang H, Hong LJ, Huang JY, Jiang Q, Tao RR, Tan C, Lu NN, Wang CK, Ahmed MM, Lu YM, et al.(Manassas, VA, USA). Migration was induced by recombinant CXCL1 (100 ng/ml, R&D systems, Catalog #: 275-GR-010/CF) or recombinant CX3CL1 (10 nM, Sino Biological, Catalog #: 10636-H08H) with or without LPS from Escherichia coli

(15) CXCR2 and its related ligands play a novel role in supporting the pluripotency and proliferation of human pluripotent stem cellsStem cells and developmentApril 15, 2015Jung JH, Lee SJ, Kim J, Lee S, Sung HJ, An J, Park Y, Kim BS.

(16) Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interactionPloS oneJanuary 1, 2015Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, et al.

(17) Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumorsMolecular cancer research : MCRDecember 1, 2014Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT.

(18) Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescenceBloodJanuary 9, 2014Sapey E, Greenwood H, Walton G, Mann E, Love A, Aaronson N, Insall RH, Stockley RA, Lord JM.

(19) CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-κB activation via EGFR-transactivated Akt signalingPloS oneJanuary 1, 2013Dong YL, Kabir SM, Lee ES, Son DS.

(20) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

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Recombinant Human CXCL1/GRO alpha Protein, CF

CXCL1/GRO alpha/KC/CINC-1 Protein

CXCL1/GRO alpha/KC/CINC-1 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CXCL1/GRO alpha/KC/CINC-1 Protein from R&D Systems, a Bio-Techne Brand

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