Recombinant Human PDGF-BB Protein, CF 220-BB-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human PDGF-BB Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $326.00Supplier Page View Company Product Page
Catalog Number220-BB-010
Size10 ug (also 50 ug, 200 ug, 1 mg)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 12 kDa, reducing conditions
Theoretical: 12.3 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NamePDGF-BB
Source/Expression SystemE. coli-derived Recombinant Human PDGF-BB Protein, CF
NCBI Full Gene Nameplatelet derived growth factor subunit B
NCBI Gene AliasesSIS, IBGC5, c-sis, SSV, PDGF-2, PDGF2
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in DiabetesAdvanced ScienceFebruary 5, 2026Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, et al.and the medium was changed every other day. Where indicated, recombinant human PDGF‐BB (R&D Systems, 220‐BB‐010) was added at a final concentration of 100 ng/mL. In parallel, cryopreserved testicular biopsy tissues

(2) Small Interfering RNA Therapy Targeting the Long Noncoding RNA SMILR for Therapeutic Intervention in Coronary Artery Bypass Graft FailureJACC: Basic to Translational ScienceNovember 1, 2025Simon D. Brown, Anna L. Malinowska, Matthew Bennett, Andrés F. Correa-Sánchez, Laia Linda Horcasitas Valencia, Aimee P. Lucignoli, Anna K. Barton, Laura Clark, Judith C. Sluimer, Scott P. Webster, et al.FBS DMEM media containing 10 ng/mL IL1α (R&D Systems 200-LA-010) and 20 ng/mL PDGF-ββ (R&D Systems 220-BB-010), and 10 μmol/L 5-ethynyl-2-deoxyuridine (EdU) (Invitrogen A10044, Thermo Fisher Scientific) where proliferation

(3) Pluripotent Stem Cell-Derived Corneal Endothelial Cells Form a Functional Corneal Endothelium in CaninesTransl Vis Sci TechnolOctober 3, 2025Muhammad Ali, Shahid Y. Khan, Hira Butt, Ryan C. Navarro, Jessica M. Izzi, S. Amer Riazuddinalpha‑granules of platelets activated during the coagulation of blood to form serum; PDGF-BB; catalog no. 220-BB-010; R&D Systems), and 10 ng/mL recombinant human Dickkopf related protein-2 (a member of the Dickkopf family

(4) A Cartilaginous Organoid System Derived From Human Expanded Pluripotent Stem Cells (hEPSCs)BIO-PROTOCOLMay 5, 2025Hong Wang, Jingyang Qiu, Yin Lin, Xiaochun Bai, Xiaocui Weiproduct format: 1 mM in ethanol) 39. Human PDGF-BB proteins (PDGF-BB) (R&D Systems, catalog number: 220-BB-010, product format: 100 μg/mL in sterile 4 mM HCl) 40. Recombinant human TGF-beta 3 protein (TGFβ3) (R&D Systems

(5) A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regenerationCell stem cellDecember 5, 2024Wei X, Qiu J, Lai R, Wei T, Lin Z, Huang S, Jiang Y, Kuang Z, Zeng H, Gong Y, et al.

(6) Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in miceCell & bioscienceOctober 15, 2024Shan F, Ye J, Xu X, Liang C, Zhao Y, Wang J, Ouyang F, Li J, Lv J, Wu Z, et al.

(7) SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodelingNature communicationsAugust 13, 2024Xu Y, Zhang H, Chen Y, Pober JS, Zhou M, Zhou JH, Min W.

(8) Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and diseaseCell Stem CellJune 6, 2024Biao Huang, Zipeng Zeng, Sunghyun Kim, Connor C. Fausto, Kari Koppitch, Hui Li, Zexu Li, Xi Chen, Jinjin Guo, Chennan C. Zhang, et al.S1786 Forskolin,Sigma-Aldrich,Cat# F3917-10MG GDNF,PeproTech,Cat# 450-10-50ug PDGF-BB,R&D Systems,Cat# 220-BB-010 R-Spondin 1,R&D Systems,Cat# 4645-RS-100 AICAR,Sigma-Aldrich,Cat# A9978 TRULI,Cayman Chemical,Cat#

(9) Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisorCell stem cellJune 6, 2024Guo T, Pei F, Zhang M, Yamada T, Feng J, Jing J, Ho TV, Chai Y.

(10) Branched chain α-ketoacids aerobically activate HIF1α signaling in vascular cellsbioRxiv : the preprint server for biologyMay 30, 2024Xiao W, Shrimali N, Oldham WM, Clish CB, He H, Wong SJ, Wertheim BM, Arons E, Haigis MC, Leopold JA, et al.

(11) Antifibrotic effects of vitamin D3 on human lung fibroblasts derived from patients with idiopathic pulmonary fibrosisThe Journal of nutritional biochemistryMarch 1, 2024Voisin T, Joannes A, Morzadec C, Lagadic-Gossmann D, Naoures CL, De Latour BR, Rouze S, Jouneau S, Vernhet L.

(12) C5a-C5AR1 axis as a potential trigger of the rupture of intracranial aneurysmsScientific reportsFebruary 7, 2024Okada A, Shimizu K, Kawashima A, Kayahara T, Itani M, Kurita H, Miyamoto S, Kataoka H, Aoki T.

(13) The lysine methyltransferase SMYD2 facilitates neointimal hyperplasia by regulating the HDAC3-SRF axisActa pharmaceutica Sinica. BFebruary 1, 2024Zhong X, Wei X, Xu Y, Zhu X, Huo B, Guo X, Feng G, Zhang Z, Feng X, Fang Z, et al.addition, LLY-507 (2 μmol/L, S7575, Selleck), RGFP966 (15 μmol/L, S7229, Selleck) and PDGF-BB (10–20 ng/mL, 220-BB-010, R&D Systems) were used to treat HASMCs. 2.3 Protein extraction and Western blot analysis Total protein

(14) Fibroblast growth factor 8b (FGF-8b) enhances myogenesis and inhibits adipogenesis in rotator cuff muscle cell populations in vitroProceedings of the National Academy of Sciences of the United States of AmericaJanuary 2, 2024Otsuka T, Kan HM, Mengsteab PY, Tyson B, Laurencin CT.

(15) The role of platelet-derived growth factor BB signaling pathway in the regulation of stem and progenitor Leydig cell proliferation and steroidogenesis in male ratsThe Journal of steroid biochemistry and molecular biologyOctober 1, 2023Li X, Quan H, He J, Li H, Zhu Q, Wang Y, Zhu Y, Ge RS.

(16) Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoidsbioRxiv : the preprint server for biologyMay 25, 2023Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, et al.S1786 Forskolin,Sigma-Aldrich,Cat# F3917-10MG GDNF,PeproTech,Cat# 450-10-50ug PDGF-BB,R&D Systems,Cat# 220-BB-010 R-Spondin 1,R&D Systems,Cat# 4645-RS-100 AICAR,Sigma-Aldrich,Cat# A9978 TRULI,"Gnedeva lab, USC",10mM-Stock MOZ-IN-3,Cayman Chemical

(17) SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodelingResearch squareMay 22, 2023Xu Y, Zhang H, Pober JS, Min W, Zhou JH.

(18) Cancer cell-derived novel periostin isoform promotes invasion in head and neck squamous cell carcinomaCancer medicineApril 1, 2023Wenhua S, Tsunematsu T, Umeda M, Tawara H, Fujiwara N, Mouri Y, Arakaki R, Ishimaru N, Kudo Y.were obtained from the following companies: TGF‐β1 (#240‐B‐010/CF), HGF (#294‐HG‐005/CF), and PDGF (#220‐BB‐010, R&D Systems, Inc.); basic FGF2 (#064–04541, FUJIFILM Wako Pure Chemical Corp.); and EGF (#100–47, Pepro

(19) The extract from Hyssopus cuspidatus Boriss. Prevents bronchial airway remodeling by inhibiting mouse bronchial wall thickening and hASMC proliferation and migrationJournal of ethnopharmacologyMarch 1, 2023Cai X, Mao Y, Shen X, Li H, He J, Zhang M.

(20) Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCsBiomaterials researchFebruary 18, 2023Yang HM, Lee JE, Kim JY, You J, Kim J, Lee HS, Yoo HM, Kong MG, Han JK, Cho HJ, et al.

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Recombinant Human PDGF-BB Protein, CF

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PDGF-BB Protein

PDGF-BB Protein

PDGF-BB Protein

Recombinant Human PDGF-BB Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human PDGF-BB Protein, CF from R&D Systems, a Bio-Techne Brand

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