IL-8/CXCL8 Protein 208-IL-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-8/CXCL8 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $191.00Supplier Page View Company Product Page
Catalog Number208-IL-010
SpeciesHuman
Molecule NameIL-8/CXCL8
Size10 ug (also 50 ug)
NCBI Full Gene NameC-X-C motif chemokine ligand 8
NCBI Gene AliasesLUCT, MDNCF, GCP1, NAF, GCP-1, NAP1, SCYB8, LYNAP, NAP-1, LECT, MONAP, IL8
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight8 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human IL-8/CXCL8 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 50 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL-1β modulates inflammatory response of human bone marrow-derived MSCs and neutrophil recruitment in vitro via NF-kB-associated signalingStem Cell Res TherApril 24, 2026Nour Hassaan, Tobias Schmidt, Zackarias Söderlund, Dimitrios Kalafatis, Lisa I. Påhlman, Stefan Scheding, Daniel J. Weiss, Robin Kahn, Sara Rolandsson Enesremoved, and cells were stimulated with IL-1β (20 ng/ml in DPBS with 0.1% Bovine Serum Albumin, cat# 208-IL-010, R&D Systems) for 1 h (RNA-sequencing) or 24 h. Unstimulated control BM-hMSCs were exposed to serum

(2) Glioblastoma Cells Induce Neuron Loss In Vivo and In VitroCancersAugust 28, 2025Rawal KN, Degorre C, Tofilon PJ.media. 2.10. The IL-8 Cytokine Treatment The neurons were treated with r-human IL-8/CXCL8 protein (208-IL-010, R&D Systems), with a concentration range of 10 ng/mL to 100 ng/mL, for 72 h. Neuron cell death was

(3) Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial InfectionAdvanced ScienceJuly 1, 2025Xue Zhai, Minghao Zhang, Kang Li, Wei Li, Xiaolong Li, Wa Gao, Zhaosheng Sun, Dan Huang, Songqian Huang, Mingli Liu, et al.093) containing 10% FBS (Gibco, A3161002C) with 1 and 10 ng mL−1 purified IL8 protein (R&D systems, 208‐IL‐010). After a 24 h‐incubation, for the bacterial killing assay, cells were washed with PBS (Sangon Biotech,

(4) Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Biomechanical Determinants of Drug Delivery to the TumorAdvanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2024Offeddu GS, Cambria E, Shelton SE, Haase K, Wan Z, Possenti L, Nguyen HT, Gillrie MR, Hickman D, Knutson CG, et al.a transient pressure difference across the MVNs before measurement of L p. Recombinant human IL8 (#208‐IL‐010, R&D Systems), IL12 (#219‐IL‐005, R&D Systems), TNFα (#210‐TA‐005, R&D Systems), CCL2 (#279‐MC‐010,

(5) Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxingNature communicationsJuly 10, 2024Reedy JL, Jensen KN, Crossen AJ, Basham KJ, Ward RA, Reardon CM, Brown Harding H, Hepworth OW, Simaku P, Kwaku GN, et al.

(6) Overexpression of Interleukin-8 Promotes the Progression of Fatty Liver to Nonalcoholic Steatohepatitis in MiceInternational journal of molecular sciencesOctober 23, 2023Cho YE, Kim Y, Kim SJ, Lee H, Hwang S.

(7) Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammationMucosal immunologyAugust 1, 2023Pajulas A, Fu Y, Cheung CCL, Chu M, Cannon A, Alakhras N, Zhang J, Ulrich BJ, Nelson AS, Zhou B, et al.

(8) Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagyJournal of extracellular vesiclesJuly 1, 2023Wang X, Xu F, Kou H, Zheng Y, Yang J, Xu Z, Fang Y, Sun W, Zhu S, Jiang Q, et al.verify the effect of IL‐8 on radioresistance, PCa cells were pretreated with a recombinant Human IL‐8 (#208‐IL‐010, Novus Biologicals, Minneapolis, USA). To inhibit IL‐8‐activated AMPK pathway, PCa cells were pretreated

(9) Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase CCell reportsMay 30, 2023Binder V, Li W, Faisal M, Oyman K, Calkins DL, Shaffer J, Teets EM, Sher S, Magnotte A, Belardo A, et al.Spy Cas9 NLS,New England Biolabs,Cat# m0646 Recombinant Human IL-8/CXCL8 Protein,R&D Systems,Cat# 208-IL-010 HA-100 dihydrochloride,Santa Cruz Biotechnology,Cat# sc-203072 dactolisib,Selleck Chemicals,Cat# S1009 ibrutinib,Selleck Chemicals

(10) Tissue CD14(+)CD8(+) T cells reprogrammed by myeloid cells and modulated by LPSNatureFebruary 1, 2023Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, et al.

(11) DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signalingJournal of leukocyte biologySeptember 1, 2022Capitano ML, Sammour Y, Ropa J, Legendre M, Mor-Vaknin N, Markovitz DM.

(12) Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistanceCell reportsJuly 19, 2022Islam R, Mishra J, Polavaram NS, Bhattacharya S, Hong Z, Bodas S, Sharma S, Bouska A, Gilbreath T, Said AM, et al.

(13) A humanized β(2) integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivoCell reportsMay 31, 2022Wen L, Marki A, Wang Z, Orecchioni M, Makings J, Billitti M, Wang E, Suthahar SSA, Kim K, Kiosses WB, et al.137-PS-050 Recombinant human ICAM-1-Fc,R&D Systems,Cat# 720-IC-050 Recombinant human IL-8,R&D Systems,Cat# 208-IL-010 Recombinant mouse P-selectin-Fc,R&D Systems,Cat# 737-PS-050 Recombinant mouse ICAM-1-Fc,R&D Systems,Cat#

(14) Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypassJournal of leukocyte biologyApril 1, 2022Lesouhaitier M, Gregoire M, Gacouin A, Coirier V, Frerou A, Piau C, Cattoir V, Dumontet E, Revest M, Tattevin P, et al.

(15) On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine stormCell reportsMarch 8, 2022Conod A, Silvano M, Ruiz I Altaba A.

(16) A chemokine regulatory loop induces cholesterol synthesis in lung-colonizing triple-negative breast cancer cells to fuel metastatic growthMolecular therapy : the journal of the American Society of Gene TherapyFebruary 2, 2022Han B, Alonso-Valenteen F, Wang Z, Deng N, Lee TY, Gao B, Zhang Y, Xu Y, Zhang X, Billet S, et al.(275-GR-010, R&D Systems), recombinant human CXCL2 (276-GB-010, R&D Systems), recombinant human CXCL8 (208-IL-010, R&D Systems), recombinant mouse Ccl2 (479-JE-010, R&D Systems), recombinant mouse Ccl7 (456-MC-010,

(17) miR-218-5p Induces Interleukin-1β and Endovascular Trophoblast Differentiation by Targeting the Transforming Growth Factor β-SMAD2 PathwayFrontiers in endocrinologyJanuary 1, 2022Shan Y, Chen Y, Brkić J, Fournier L, Ma H, Peng C.hr after the transfection. In some experiments, cells were also treated with recombinant human IL1β (208-IL-010), TGFβ1 (243-B-002), TGFβ2 (302-B2-002), TGFβ3 (243-B3-002), or Activin A (338-AC-010) (all purchased

(18) Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cellsScientific reportsJuly 22, 2021Lee J, Choi JA, Ju HH, Kim JE, Paik SY, Rao PV.POAG. Methods Chemicals MCP-1 (Cat. no.279-MC-010; R&D systems, Minneapolis MN), IL-8 (Cat. No. 208-IL-010; R&D systems), recombinant TGF-β1 (Cat. No. 240-B-010; R&D system), and Y-27632 (Cat. No. 1254; Tocris Bioscience

(19) Granulocyte and monocyte adsorptive apheresis induces apoptosis of neutrophils and release of a novel chemoattractant for desensitization of interleukin-8 response - In vitro and in vivo resultsCytokineMarch 1, 2021Kashiwagi N, Saito F, Maegawa H, Kaneda K.

(20) Sequential Protein Capture in Multiplex Single Molecule Arrays: A Strategy for Eliminating Assay Cross-ReactivityAdvanced healthcare materialsFebruary 1, 2021Gilboa T, Maley AM, Ogata AF, Wu C, Walt DR.of Standard Multiplex Simoa Assay: Human recombinant protein standards for IL-7 (207-IL-005), IL-8 (208-IL-010), and IL-10 (217-IL-005) were purchased from R&D Systems. Proteins were received lyophilized, reconstituted

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Recombinant Human IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-8/CXCL8 Protein from R&D Systems, a Bio-Techne Brand

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