IL-6 Protein 206-IL-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-6 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $282.00Supplier Page View Company Product Page
Catalog Number206-IL-010
SpeciesHuman
Size10 ug (also 50 ug, 200 ug, 1 mg)
Source/Expression SystemE. coli-derived Recombinant Human IL-6 Protein
Molecule NameIL-6
NCBI Full Gene Nameinterleukin 6
NCBI Gene AliasesCDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
FormatLyophilized from a 0.2 µm filtered solution in PBS and NaCl with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 50 ug, 200 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Inhibition of STAT3-mediated glycolysis by bruceine D suppresses non-small-cell lung cancer progression in vitro and in vivoCancer Biol TherDecember 31, 2026Yu Zhu, Xuan Xu, Xiaofan Hong, Jiayi Zhang, Yi Zhou, Aofeng Sun, Yihan Ye, Yini Xu, Huanhai Xu, Haiyang Zhao, et al.under a fluorescent microscope. Recombinant human IL-6 was purchased from Bio-Techne China Co., Ltd. (206-IL-010). Molecular docking Molecular docking was performed using AutoDock Vina 1.0.2 software. Data representing

(2) Imperfect Maturation of Erythroid Progenitors in Patients with Cirrhosis-Associated AnemiaCurr Issues Mol BiolMay 14, 2026Deepika Lal, Jaswinder Singh Maras, Rakhi Maiwall, Anupam Kumar, Chhagan BihariMinneapolis, MN, USA), 100 ng/mL rhFLT-3 ligand (11343305; ImmunoTools, Friesoythe, Germany), 20 ng/mL rhIL-6 (206-IL-010; R&D System, Minneapolis, MN, USA) at 37 °C in 5% CO2 to promote cell expansion. After this initial

(3) A human synovial tendon-on-a-chip models key features of peritendinous adhesions and offers a new approach methodology for testing anti-fibrotic drugsbioRxivApril 7, 2026Isabelle Linares, Anabelle Creveling, Abdikadir Osman, Nathan Grandwetter, Benjamin L. Miller, James L. McGrath, Hani A. AwadAll conditions except the negative vehicle control were incubated with 10 ng ml−1 IL-6 (R&D Systems, 206-IL-010) + respective drug treatment for 30 min. Cells were then promptly fixed with 4% paraformaldehyde and

(4) IL-6 trans-Signaling Regulates Neutrophilic Inflammation in Alcohol-Associated HepatitisThe American Journal of PathologyJanuary 1, 2026Gaurav Sarode, Ming-Fo Hsu, Fawaz G. Haj, Sergio Barace, Josepmaria Argemi, Mengfei Liu, Prisha Pandita, Sheng Cao, Vijay H. Shah, Dorina Gui, et al.treatment, recombinant human IL-6 protein 1 ng/mL (low dose), IL-6 20 ng/mL (high dose) (catalog number 206-IL-010; R&D Systems), hyper (h)–IL-6 [recombinant human IL-6R α/IL-6 chimera; hIL-6] 1 ng/mL (low dose), and

(5) Chronic IL-1 Exposure Attenuates RELA- and STAT3-Dependent Synergistic Cytokine Signaling in Prostate Cancer Cell LinesCancers (Basel)November 26, 2025Stephanie Akemi Yamauchi, Haley Dahl-Wilkie, Mohamed Hussien Mohamed Zaky, Vivian Liu, Adora Onuogu, Ahmed Abdi, Shreya Billa, Rahael Javaid, Sheza Siddiqui, Chisom Mbah, et al.1110-01A-100), IL-1β (GoldBio, St. Louis, MO, USA; 1110-01B-100), or IL-6 (R&D Systems, Minneapolis, MN, USA; 206-IL-010) was resuspended in 0.1% bovine serum albumin (BSA) (Thermo Fisher Scientific, Fair Lawn, NJ, USA; BP

(6) Humoral determinants of checkpoint immunotherapyNatureAugust 1, 2025Dai Y, Aizenbud L, Qin K, Austin M, Jaycox JR, Cunningham J, Wang EY, Zhang L, Fischer S, Carroll SM, et al.

(7) TGF-β Drives Myofibroblast Activation and Inflammatory Mediator Production in Vulvar Lichen SclerosusAJOG Global ReportsJuly 21, 2025Sarah A. Fischer, Zahra Mahamed, Ashley Updike, Briana Boachie, Caitriona Greene, Ruth Agwaze, Kira Parr, Tanzy Love, Adrienne D. Bonham, Mitchell A. Linder, et al.IL-6 and IL-8 cytokines using the following reagents: recombinant human IL-6 standard (R&D Systems #206-IL-010), rat anti-human IL-6 antibody (BD Pharmingen, Franklin Lakes, NJ, #554543), biotin rat anti-human IL-6

(8) Reconstructed Human Skin Models to Study Superficial and Deep Skin Wound Healing In VitroWound Repair RegenJune 5, 2025Maaike Waasdorp, Irit Vahav, Joline Paulina Nugteren‐Boogaard, Sanne Roffel, Susan GibbsMinneapolis, Minnesota). Paired ELISA antibodies and recombinant proteins were used for IL‐6 (BAF206; MAB206; 206‐IL‐010), CCL2 (MAB679; BAF279), CCL5 (278‐RN‐010; BAF278), VEGF (BAF293; AF‐293‐NA; 293‐VE‐10) and TIMP‐1 (MAB970;

(9) Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusionRespir ResMay 10, 2025Qinpei Cheng, Xueying Zuo, Zimu Wang, Wanjun Lu, Yuxin Jiang, Jiaxin Liu, Xinying Li, Qiuli Xu, Suhua Zhu, Xin Liu, et al.dioxide (CO2). For in vitro conditions, the following reagents were used: recombinant human IL-6 protein (206-IL-010, R&D Systems, USA), S3I-201 (S1155, Selleck Chemicals, USA), and tocilizumab (Roche, Switzerland). Mice

(10) SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation responseCell ReportsApril 22, 2025Nurul Khalida Ibrahim, Sabine Schreek, Buesra Cinar, Anna Sophie Stasche, Su Hyun Lee, Andre Zeug, Tim Dolgner, Julia Niessen, Evgeni Ponimaskin, Halyna Shcherbata, et al.,Thermo Fisher Scientific,Cat#T10282 Human FLT3,R&D systems,Cat#398-FK Human Interleukin-7,R&D systems,Cat#206-IL-010 Human stem cell factor,R&D systems,Cat#255-SC Human R-Spondin 3,R&D systems,Cat#3500-RS Human Wnt3a,R&D

(11) BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugateCell stem cellFebruary 6, 2025Demirci S, Zeng J, Palchaudhuri R, Wu C, Abraham DM, Hayal TB, Essawi K, Nguyen MA, Stasula U, Chu R, et al.

(12) Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male miceNature communicationsJanuary 11, 2025Yin W, Xu H, Bai Z, Wu Y, Zhang Y, Liu R, Wang Z, Zhang B, Shen J, Zhang H, et al.effects of N-Acetyl-L-cysteine (NAC, Sigma) on the phosphorylation of STAT1 and STAT3 stimulated by IL-6 (206-IL-010, R&D Systems) or IFN-γ (ab9659, Abcam), HepG2 cells were incubated with serum-free medium for 30 min,

(13) Blockade of interleukin-6 (IL-6) signaling in dedifferentiated liposarcoma (DDLPS) decreases mouse double minute 2 (MDM2) oncogenicity via alternative splicingPloS oneJanuary 1, 2025Zewdu A, Braggio D, Lopez G, Batte K, Khurshid S, Costas C de Faria F, Bid HK, Koller D, Casadei L, Ladner KJ, et al.

(14) PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesityNature communicationsNovember 4, 2024Gilglioni EH, Li A, St-Pierre-Wijckmans W, Shen TK, Pérez-Chávez I, Hovhannisyan G, Lisjak M, Negueruela J, Vandenbempt V, Bauzá-Martinez J, et al.obtained from Sigma-Aldrich. Recombinant murine IFNγ (315-05-100ug, PeproTech) and recombinant human IL6 (206-IL-010, R&D Systems) and FBP1 inhibitor (5-Chloro-2-(N-(2,5-dichlorobenzenesulfonamido))-benzoxazole, Santa

(15) STAT3 Protein-Protein Interaction Analysis Finds P300 as a Regulator of STAT3 and Histone 3 Lysine 27 Acetylation in PericytesBiomedicinesSeptember 14, 2024Kundu G, Ghasemi M, Yim S, Rohil A, Xin C, Ren L, Srivastava S, Akinfolarin A, Kumar S, Srivastava GP, et al.37 °C incubator with 5% CO2 and 37% relative humidity. IL-6 was purchased from R&D Systems (Cat. No. 206-IL-010, Minneapolis, MN, USA) and resuspended per the manufacturer’s instructions. A-485 was purchased from

(16) Plug-and-play protein biosensors using aptamer-regulated in vitro transcriptionNature communicationsSeptember 12, 2024Lee H, Xie T, Kang B, Yu X, Schaffter SW, Schulman R.

(17) Optimization of Nanowell-Based Label-Free Impedance Biosensor Based on Different Nanowell StructuresBiosensors (Basel)September 4, 2024Ali Fardoost, Hassan Raji, Mehdi Javanmardexperiment, Monoclonal Human/Primate IL-6 Antibody (MAB206, R&D Systems) and Recombinant Human IL-6 Protein (206-IL-010, R&D Systems) were used as a target macromolecule to be detected by the designed and fabricated sensor.

(18) Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cellsCell reportsAugust 27, 2024Kent GM, Atkins MH, Lung B, Nikitina A, Fernandes IM, Kwan JJ, Andrews TS, MacParland SA, Keller GM, Gage BK.

(19) Paracrine Activation of STAT3 Drives GM-CSF Expression in Breast Carcinoma Cells, Generating a Symbiotic Signaling Network with Breast Carcinoma-Associated FibroblastsCancersAugust 22, 2024Osuala KO, Chalasani A, Aggarwal N, Ji K, Moin K.Stattic and niclosamide were prepared in DMEM/F12 immediately prior to use. Recombinant IL-6 (cat#, 206-IL-010, R&D Systems, Minneapolis, MN, USA) was prepared from diluted frozen stocks. Recombinant GM-CSF (cat#,

(20) Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activityBlood cancer journalAugust 19, 2024Lind J, Aksoy O, Prchal-Murphy M, Fan F, Fulciniti M, Stoiber D, Bakiri L, Wagner EF, Zwickl-Traxler E, Sattler M, et al.

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Recombinant Human IL-6 Protein

IL-6 Protein

IL-6 Protein

IL-6 Protein

IL-6 Protein

IL-6 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-6 Protein from R&D Systems, a Bio-Techne Brand

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