Recombinant Mouse PD-1 Fc Chimera Protein, CF 1021-PD-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse PD-1 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $456.00Supplier Page View Company Product Page
Catalog Number1021-PD-100
Size100 ug
ApplicationsBinding Activity
FormatLyophilized from a 0.2 µm filtered solution in Tris-HCL, NaCl and EDTA with Trehalose
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 66 kDa, reducing conditions
Theoretical: 43 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesMouse
Molecule NamePD-1
Source/Expression SystemNS0-derived Recombinant Mouse PD-1 Fc Chimera Protein, CF
NCBI Full Gene Nameprogrammed cell death 1
NCBI Gene AliasesPdc1, Ly101, PD-1
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Co-Targeting Luminal B Breast Cancer with S-Adenosylmethionine and Immune Checkpoint Inhibitor Reduces Primary Tumor Growth and Progression, and Metastasis to Lungs and BoneCancersDecember 22, 2022Mehdi A, Attias M, Arakelian A, Piccirillo CA, Szyf M, Rabbani SA.antibody, and SAM+anti-PD-L1. Eo771, EMT6, and R221A cells were supplemented with 0.2 μM rPD-1 (cat# 1021-PD-100, R&D systems, Minneapolis, MN, USA) on day 3, which was followed with 50 μg anti-PD-L1 on day 4. The

(2) The multi-specific V_H-based Humabody CB213 co-targets PD1 and LAG3 on T cells to promote anti-tumour activityBritish journal of cancerMay 1, 2022Edwards CJ, Sette A, Cox C, Di Fiore B, Wyre C, Sydoruk D, Yadin D, Hayes P, Stelter S, Bartlett PD, et al.his-tagged LAG3 (Acro Biosystems LA3-M52H5) and recombinant mouse-PD1-human-Fc chimaera (R&D Systems, 1021-PD-100) proteins were also assessed, as was IgG from human serum (Sigma Aldrich I2511). Targets in sodium acetate

(3) The Programmed Cell Death Ligand-1/Programmed Cell Death-1 Pathway Mediates Pregnancy-Induced Analgesia via Regulating Spinal Inflammatory CytokinesAnesthesia and analgesiaNovember 1, 2021Tan H, Ding Z, Zhang C, Yan J, Yang Y, Li P.enzyme-linked immunosorbent assay (ELISA) kit (catalog: CSU-EL004911MO) was purchased from CUSABIO. Mouse PD-1 (5 µg, catalog: 1021-PD-100) was obtained from R&D Systems. RMP1-14 (20 µg, catalog: BE0146) was purchased from Bio X Cell. For

(4) Dual and Opposite Costimulatory Targeting with a Novel Human Fusion Recombinant Protein Effectively Prevents Renal Warm Ischemia Reperfusion Injury and Allograft Rejection in Murine ModelsInternational journal of molecular sciencesJanuary 26, 2021Guiteras J, De Ramon L, Crespo E, Bolaños N, Barcelo-Batllori S, Martinez-Valenzuela L, Fontova P, Jarque M, Torija A, Bestard O, et al.

(5) Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without ToxicityBiomedicinesDecember 2, 2020Silva-Pilipich N, Martisova E, Ballesteros-Briones MC, Hervas-Stubbs S, Casares N, González-Sapienza G, Smerdou C, Vanrell L.

(6) DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct ExposureMolecular therapy : the journal of the American Society of Gene TherapyApril 8, 2020Jacobs L, De Smidt E, Geukens N, Declerck P, Hollevoet K.

(7) Enhanced Anticancer Effect of a Combination of S-adenosylmethionine (SAM) and Immune Checkpoint Inhibitor (ICPi) in a Syngeneic Mouse Model of Advanced MelanomaFrontiers in oncologyJanuary 1, 2020Mehdi A, Attias M, Mahmood N, Arakelian A, Mihalcioiu C, Piccirillo CA, Szyf M, Rabbani SA.cells in these wells were treated accordingly. B16-F1 cells were stimulated with 0.2 μM rPD-1 (catalog #1021-PD-100, R&D systems, USA) on day 3 to stimulate the PD-1/PD-L1 pathway before adding 50 μg anti-PD-L1 on day

(8) CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cellseLifeNovember 24, 2017Yuan X, Yang BH, Dong Y, Yamamura A, Fu W.Ig,R and D Systems,CAT#: 434-CT-200/CF, "peptide, recombinant protein",PD-1 Ig,R and D Systems,CAT#: 1021-PD-100, "peptide, recombinant protein",VISTA Ig,R and D Systems,CAT#: 7005-B7-050, "peptide, recombinant

(9) Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicityNature communicationsFebruary 17, 2015Matsumura T, Sugawara Y, Yutani M, Amatsu S, Yagita H, Kohda T, Fukuoka S, Nakamura Y, Fukuda S, Hase K, et al.

(10) Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responsesImmunityJuly 1, 2007Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ.

(11) BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammationJournal of immunology (Baltimore, Md. : 1950)February 1, 2007Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL.

Write a Review

(1)

5/20/20191021-PD (PD1-Fc chimera) Binds to PDL1-Fc Chimera - R&D Systems Anonymous ReviewerThe reagent performs well and binds its ligand as expected.

Recombinant Mouse PD-1 Fc Chimera Protein, CF

PD-1 Fc Chimera Protein

PD-1 Fc Chimera Protein

Recombinant Mouse PD-1 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

Citations (11)

Reviews

Recombinant Mouse PD-1 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map