Recombinant Human Semaphorin 3A Fc Chimera Protein, CF 1250-S3-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Semaphorin 3A Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $445.00Supplier Page View Company Product Page
Catalog Number1250-S3-025
Size25 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in Tris, NaCl and Tween® 20
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 120 kDa, 90 kDa and 37 kDa, reducing conditions
Theoretical: 113.5 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameSemaphorin 3A
Source/Expression SystemNS0-derived Recombinant Human Semaphorin 3A Fc Chimera Protein, CF
NCBI Full Gene Namesemaphorin 3A
NCBI Gene AliasesSEMA1, SemD, Hsema-I, HH16, Hsema-III, COLL1, SEMAL, coll-1, SEMAIII, SEMAD
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Short 2'-O-methyl/LNA oligomers as highly-selective inhibitors of miRNA production in vitro and in vivoNucleic acids researchJune 10, 2024Koralewska N, Corradi E, Milewski MC, Masante L, Szczepanska A, Kierzek R, Figlerowicz M, Baudet ML, Kurzynska-Kokorniak A.

(2) Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3ADevelopmental dynamics : an official publication of the American Association of AnatomistsJanuary 1, 2023Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM.polycarbonate membrane filters (Sterlitech PCT0213100). Then, 25 nM SEMA3A-Fc chimera protein (R&D Systems 1250-S3–025), control human IgG-Fc (Jackson ImmunoResearch, 009–000-008), 5 μM AMPA receptor inhibitor NBQX (Abcam

(3) Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injuryExperimental eye researchJune 1, 2022Guaiquil VH, Xiao C, Lara D, Dimailig G, Zhou Q.treatments. Cells were left untreated (control) or treated with 50 ng/ml rhSema3A (R&D systems cat #1250-S3-025), 25 ng/ml rmNetrin-4 (Cat# 1132-N4-025/CF) or 25 ng/ml rhEphrinB2 (Cat#7397-EB-050). The plate was

(4) A Potential Role of Semaphorin 3A during Orthodontic Tooth MovementInternational journal of molecular sciencesAugust 2, 2021Şen S, Lux CJ, Erber R.

(5) Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neuronsScientific reportsJune 21, 2021Ivakhnitskaia E, Chin MR, Siegel D, Guaiquil VH.

(6) Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosisNature communicationsApril 23, 2021Ferreira APA, Casamento A, Carrillo Roas S, Halff EF, Panambalana J, Subramaniam S, Schützenhofer K, Chan Wah Hak L, McGourty K, Thalassinos K, et al.

(7) PlexinA4-Semaphorin3A-mediated crosstalk between main cortical interneuron classes is required for superficial interneuron laminationCell reportsJanuary 26, 2021Limoni G, Murthy S, Jabaudon D, Dayer A, Niquille M.

(8) Semaphorin 3A mediated brain tumor stem cell proliferation and invasion in EGFRviii mutant gliomasBMC cancerDecember 10, 2020Higgins DMO, Caliva M, Schroeder M, Carlson B, Upadhyayula PS, Milligan BD, Cheshier SH, Weissman IL, Sarkaria JN, Meyer FB, et al.

(9) Reconsideration of the Semaphorin-3A Binding Motif Found in Chondroitin Sulfate Using Galnac4s-6st-Knockout MiceBiomoleculesOctober 30, 2020Nadanaka S, Miyata S, Yaqiang B, Tamura JI, Habuchi O, Kitagawa H.

(10) How scars shape the neural landscape: Key molecular mediators of TGF-β1's anti-neuritogenic effectsPloS oneJanuary 1, 2020Jeon KI, Huxlin KR.primaria culture dish) were pretreated with 1, 10 ng/ml TGF-β1 (240-B010, R&D Systems) or 10ng/ml Sema3A (1250-S3-025, R&D Systems). After 1hr, either 0.5ng/ ml or 50ng/ml rNGF (R&D Systems) was added for 1 day. Phase-contrast

(11) Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1Nature communicationsJuly 26, 2019Leclerc M, Voilin E, Gros G, Corgnac S, de Montpréville V, Validire P, Bismuth G, Mami-Chouaib F.activated T cells were incubated for 30 min to 1 h either with BSA (Merck) or Sema-3A-Fc (R&D systems 1250-S3-025, 100 ng/ml), and their ability to migrate toward the human rCXCL12 (Peprotech 300-28 A, 50 nm) was evaluated.

(12) STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth ConesThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 26, 2019Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, et al.

(13) B7-H4 Modulates Regulatory CD4⁺ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 ComplexJournal of immunology (Baltimore, Md. : 1950)August 1, 2018Podojil JR, Chiang MY, Ifergan I, Copeland R, Liu LN, Maloveste S, Langermann S, Liebenson D, Balabanov R, Chi H, et al.

(14) Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer CellsScientific reportsMay 8, 2018Grindel BJ, Martinez JR, Tellman TV, Harrington DA, Zafar H, Nakhleh L, Chung LW, Farach-Carson MC.

(15) Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3AScientific reportsMay 2, 2018de Ridder D, Marino S, Bishop RT, Renema N, Chenu C, Heymann D, Idris AI.

(16) Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytesRheumatology (Oxford, England)May 1, 2018Tang MW, Malvar Fernández B, Newsom SP, van Buul JD, Radstake TRDJ, Baeten DL, Tak PP, Reedquist KA, García S.

(17) Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in developmentPloS oneJanuary 1, 2018Zhang M, Zhou Q, Luo Y, Nguyen T, Rosenblatt MI, Guaiquil VH.

(18) Effects of neuroactive agents on axonal growth and pathfinding of retinal ganglion cells generated from human stem cellsScientific reportsDecember 1, 2017Yokoi T, Tanaka T, Matsuzaka E, Tamalu F, Watanabe SI, Nishina S, Azuma N.

(19) MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritisExperimental & molecular medicineAugust 4, 2017Hong BK, You S, Yoo SA, Park D, Hwang D, Cho CS, Kim WU.

(20) SEMA3A partially reverses VEGF effects through binding to neuropilin-1Stem cell researchJuly 1, 2017Palodetto B, da Silva Santos Duarte A, Rodrigues Lopes M, Adolfo Corrocher F, Marconi Roversi F, Soares Niemann F, Priscila Vieira Ferro K, Leda Figueiredo Longhini A, Melo Campos P, Favaro P, et al.

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Semaphorin 3A Fc Chimera Protein

Semaphorin 3A Fc Chimera Protein

Semaphorin 3A Fc Chimera Protein

Recombinant Human Semaphorin 3A Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human Semaphorin 3A Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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