Recombinant Human B7-2/CD86 Fc Chimera Protein, CF 141-B2-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human B7-2/CD86 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $412.00Supplier Page View Company Product Page
Catalog Number141-B2-100
SpeciesHuman
Size100 ug
Molecule NameB7-2/CD86
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 85-95 kDa, reducing conditions
Theoretical: 52.7 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human B7-2/CD86 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameCD86 molecule
NCBI Gene AliasesB7-2, B7.2, B70, CD28LG2, LAB72

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The homodimer interfaces of costimulatory receptors B7 and CD28 control their engagement and pro-inflammatory signalingJournal of biomedical scienceJune 28, 2023Popugailo A, Rotfogel Z, Levy M, Turgeman O, Hillman D, Levy R, Arad G, Shpilka T, Kaempfer R.

(2) Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid ArthritisJournal of immunology researchJanuary 1, 2018O'Dwyer R, Kovaleva M, Zhang J, Steven J, Cummins E, Luxenberg D, Darmanin-Sheehan A, Carvalho MF, Whitters M, Saunders K, et al.plate washed twice with PBS. For the secondary coating, 4 μg/ml rhB7-2/ CD86-Fc (R&D Systems cat. #141-B2-100) plus 500 ng/ml rhB7-H2-Fc (R&D Systems cat. #165-B7-100) was added in PBS at 100 μl/well and incubated

(3) A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn BindingJournal of immunology (Baltimore, Md. : 1950)January 1, 2017Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, et al.

(4) An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation SyndromeFrontiers in immunologyJanuary 1, 2017Sic H, Speletas M, Cornacchione V, Seidl M, Beibel M, Linghu B, Yang F, Sevdali E, Germenis AE, Oakeley EJ, et al.

(5) Genomic landscape of cutaneous T cell lymphomaNature geneticsSeptember 1, 2015Choi J, Goh G, Walradt T, Hong BS, Bunick CG, Chen K, Bjornson RD, Maman Y, Wang T, Tordoff J, et al.binding of human CD80-Fc (catalog number 140-B1-100; R&D Systems) and human CD86-Fc (catalog number 141-B2-100; R&D Systems) to these cells were performed as previously described29,58. The secondary antibody used

(6) The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysmJournal of internal medicineApril 1, 2007Sakthivel P, Shively V, Kakoulidou M, Pearce W, Lefvert AK.

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Recombinant Human B7-2/CD86 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human B7-2/CD86 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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