ICAM-1/CD54 Fc Chimera Protein 720-IC-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemICAM-1/CD54 Fc Chimera Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $282.00Supplier Page View Company Product Page
Catalog Number720-IC-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size50 ug (also 200 ug, 1 mg)
Molecule NameICAM-1/CD54
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 110-125 kDa, reducing conditions
Theoretical: 76 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human ICAM-1/CD54 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 weeks, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameintercellular adhesion molecule 1
NCBI Gene AliasesBB2, CD54, P3.58

Specifications/Features

Available conjugates: Sizes Available: 50 ug (also 200 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Adoptive γδ T cell therapy controls cytomegalovirus infection in preclinical transplantation modelsNature CommunicationsFebruary 17, 2026Gabriel Marsères, Coline Gentil, Claire Tinevez, Maxime Courant, Anaïs Cosentino, Selma Cornillot-Clément, Victor Bigot, Vincent Pitard, Atika Zouine, Julien Izotte, et al.different concentrations of coated recombinant human ICAM-1 FC Chimera (R&D Systems, catalog number 720-IC-050), or with 25 ng/mL PMA (Sigma, catalog number P8139) and 1 µg/mL ionomycin (Sigma, catalog number A23187). Transwell

(2) Identifying a potential role of immune cells in gadolinium deposition within the brainFluids Barriers CNSJuly 29, 2025Dixy Parakkattel, Nico Ruprecht, Peter Broekmann, Sarah Guimbal, Chiara Stüdle, Sasha Soldati, Johannes T. Heverhagen, Britta Engelhardt, Hendrik von Tengg-Kobligkcoated directly with either 10 µg/mL human recombinant ICAM-1/CD54 Fc chimera protein (Catalog no.: 720-IC-050, R&D systems) or human recombinant VCAM-1 Fc chimera protein (Catalog no.: 553706, BioLegend) in PBS

(3) Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosisNature communicationsJuly 12, 2025Chouaib AA, Chang HF, Khamis OM, Alawar N, Echeverry S, Demeersseman L, Elizarova S, Daniel JA, Tian Q, Lipp P, et al.

(4) Targeted localization of the mother centrosome in CD8(+) T cells undergoing asymmetric cell division promotes memory formationCell reportsJanuary 28, 2025Barandun N, Meier B, Stehli G, Gräbnitz F, Zangger N, Oxenius A.

(5) Chronic stimulation desensitizes β2-adrenergic receptor responses in natural killer cellsEuropean journal of immunologyDecember 1, 2024Jürgens M, Claus M, Wingert S, Niemann JA, Picard LK, Hennes E, Haasler I, Hellwig B, Overbeck N, Reinders J, et al.

(6) Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and ReperfusionInternational journal of molecular sciencesJuly 7, 2023Wilkins GC, Gilmour J, Giannoudaki E, Kirby JA, Sheerin NS, Ali S.

(7) An isoform of the giant protein titin is a master regulator of human T lymphocyte traffickingCell reportsMay 30, 2023Toffali L, D'Ulivo B, Giagulli C, Montresor A, Zenaro E, Delledonne M, Rossato M, Iadarola B, Sbarbati A, Bernardi P, et al.

(8) Asymmetric cell division safeguards memory CD8 T cell developmentCell reportsMay 30, 2023Gräbnitz F, Stark D, Shlesinger D, Petkidis A, Borsa M, Yermanos A, Carr A, Barandun N, Wehling A, Balaz M, et al.

(9) A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogenyJCI insightFebruary 22, 2023Rohwedder I, Wackerbarth LM, Heinig K, Ballweg A, Altstätter J, Ripphahn M, Nussbaum C, Salvermoser M, Bierschenk S, Straub T, et al.

(10) Impaired migratory phenotype of CD4(+) T cells in Parkinson's diseaseNPJ Parkinson's diseaseDecember 10, 2022Mamula D, Khosousi S, He Y, Lazarevic V, Svenningsson P.transferred to µ-slides (Ibidi, #81501) previously coated with human ICAM-1 (10 μg/mL; R&D Systems, #720-IC-050), blocked with 2% BSA and washed with HBSS-based buffer (without Ca2+/Mg2+, supplemented with 0.2% BSA).

(11) β(2)-Integrin Adhesive Bond Tension under Shear Stress Modulates Cytosolic Calcium Flux and Neutrophil Inflammatory ResponseCellsSeptember 9, 2022Morikis VA, Chen SJ, Madigan J, Jo MH, Werba LC, Ha T, Simon SI.

(12) A humanized β(2) integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivoCell reportsMay 31, 2022Wen L, Marki A, Wang Z, Orecchioni M, Makings J, Billitti M, Wang E, Suthahar SSA, Kim K, Kiosses WB, et al.proteins" ,, Recombinant human P-selectin-Fc,R&D Systems,Cat# 137-PS-050 Recombinant human ICAM-1-Fc,R&D Systems,Cat# 720-IC-050 Recombinant human IL-8,R&D Systems,Cat# 208-IL-010 Recombinant mouse P-selectin-Fc,R&D Systems,Cat#

(13) The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migrationScience advancesApril 15, 2022Mastrogiovanni M, Vargas P, Rose T, Cuche C, Esposito E, Juzans M, Laude H, Schneider A, Bernard M, Goyard S, et al.

(14) Mitofusin-2 regulates leukocyte adhesion and β2 integrin activationJournal of leukocyte biologyApril 1, 2022Liu W, Hsu AY, Wang Y, Lin T, Sun H, Pachter JS, Groisman A, Imperioli M, Yungher FW, Hu L, et al.

(15) LFA-1 and kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motorsJournal of cell scienceAugust 15, 2021Eidell KP, Lovy A, Sylvain NR, Scangarello FA, Muendlein HI, Ophir MJ, Nguyen K, Seminario MC, Bunnell SC.

(16) Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxationCell reportsJuly 13, 2021Lanz AL, Masi G, Porciello N, Cohnen A, Cipria D, Prakaash D, Bálint Š, Raggiaschi R, Galgano D, Cole DK, et al.11161D Human serum,Sigma Aldrich,Cat # H4522 "ICAM-1 protein, recombinant human",R&D Systems,Cat # 720-IC-050 Imidazole,Sigma Aldrich,Cat # I202-500G Iodoacetamide,Sigma Aldrich,Cat # I6125 Ionomycin,Sigma Aldrich,Cat

(17) Morphological profiling of human T and NK lymphocytes by high-content cell imagingCell reportsJuly 6, 2021German Y, Vulliard L, Kamnev A, Pfajfer L, Huemer J, Mautner AK, Rubio A, Kalinichenko A, Boztug K, Ferrand A, et al.

(18) Irisin supports integrin-mediated cell adhesion of lymphocytesBiochemistry and biophysics reportsJuly 1, 2021Myint PK, Ito A, Appiah MG, Obeng G, Darkwah S, Kawamoto E, Gaowa A, Park EJ, Shimaoka M.

(19) Calcineurin inhibitors suppress acute graft-versus-host disease via NFAT-independent inhibition of T cell receptor signalingThe Journal of clinical investigationJune 1, 2021Otsuka S, Melis N, Gaida MM, Dutta D, Weigert R, Ashwell JD.(SIINFEKL, OVA-p) were purchased from Peptide 2.0. Recombinant human ICAM1-CD54-Fc chimera (catalog 720IC-050) was purchased from R&D Systems. CsA for in vitro experiments was obtained from MilliporeSigma (catalog

(20) Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageingNature communicationsMay 11, 2021Borsa M, Barandun N, Gräbnitz F, Barnstorf I, Baumann NS, Pallmer K, Baumann S, Stark D, Balaz M, Oetiker N, et al.

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ICAM-1/CD54 Fc Chimera Protein

ICAM-1/CD54 Fc Chimera Protein

ICAM-1/CD54 Fc Chimera Protein

ICAM-1/CD54 Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (74)

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ICAM-1/CD54 Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

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