Recombinant Human FGF-4 Protein 235-F4-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human FGF-4 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $328.00Supplier Page View Company Product Page
Catalog Number235-F4-025
SpeciesHuman
Size25 ug (also 50 ug, 200 ug, 1 mg)
Molecule NameFGF-4
NCBI Full Gene Namefibroblast growth factor 4
NCBI Gene AliasesK-FGF, HST-1, FGF-4, HSTF-1, KFGF, HST, HBGF-4, HSTF1
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 16 kDa, reducing conditions
Theoretical: 17 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human FGF-4 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Endogenous retrovirus IAP forms virus-like particles and traffics across the maternal-fetal barrierbioRxivDecember 26, 2025Abby J. Bergman, Guillaume Cornelis, Julie C. Bakerand 50uM 2-mercaptoethanol (Fisher Scientific 21–985-023) supplemented with 25ng/mL Fgf4 (R&D Systems 235-F4–025), 1ug/mL ActivinA (R&D 338-AC-050), and 10ng/mL Heparin (Sigma-Aldrich H3149–10KU). To introduce plasmid

(2) Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm stateNature cell biologySeptember 1, 2025Gao Y, Li M, Guan W, Guo W, Wei S, Yan F, Han W, Zhang X, Yin T, Dang Y, et al.

(3) Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotencyGenome BiolApril 28, 2025Nadia Omega Cipta, Yingying Zeng, Ka Wai Wong, Zi Hao Zheng, Yao Yi, Tushar Warrier, Jian Zhou Teo, Jia Hao Jackie Teo, Yee Jiun Kok, Xuezhi Bi, et al.basal medium (Takara Bio, Y40002), 50% KSOM (Millipore, MR- 020P- 5D), 12.5 ng/mL rhFGF4 (R&D Systems 235-F4 - 025), 0.5 µg/mL heparin, 3 μM CHIR99021 and 2 μM Y- 27632 (Reagents Direct, 53-B80 - 50). The cells were

(4) Lineage-specific CDK activity dynamics characterize early mammalian developmentCell ReportsApril 22, 2025Bechara Saykali, Andy D. Tran, James A. Cornwell, Matthew A. Caldwell, Paniz Rezvan Sangsari, Nicole Y. Morgan, Michael J. Kruhlak, Steven D. Cappell, Sergio Ruiz(Ro3306),Sigma-Aldrich,SML0569 Palbociclib (PD-0332991),Selleckchem,S1116 Recombinant Human FGF4,R&D Systems,235-F4-025 Heparin,Sigma-Aldrich,H3149-10KU M2,EMD Millipore,MR-015-D EmbryoMax KSOM,EMD Millipore,MR-106-D Silicon

(5) Placental extracellular vesicles promote cardiomyocyte maturation and fetal heart developmentCommunications BiologyOctober 3, 2024Mariyan J. Jeyarajah, Violet S. Patterson, Gargi Jaju Bhattad, Lin Zhao, Shawn N. Whitehead, Stephen J. RenaudMemorial Institute (RPMI)-1640 media supplemented with 20% FBS, 25 ng/mL fibroblast growth factor 4 (235-F4-025, FGF4, R&D systems, Minneapolis, MN, USA), 1 µg/mL heparin, 10 ng/mL activin A (338-AC-10, R&D systems),

(6) Non-pituitary growth hormone enables colon cell senescence evasionAging cellAugust 1, 2024Chesnokova V, Zonis S, Apaydin T, Barrett R, Melmed S.

(7) An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cellsCell reportsJuly 23, 2024Moerkens R, Mooiweer J, Ramírez-Sánchez AD, Oelen R, Franke L, Wijmenga C, Barrett RJ, Jonkers IH, Withoff S.

(8) Reprogramming human urine cells into intestinal organoids with long-term expansion ability and barrier functionHeliyonJuly 15, 2024Zhang R, Chen Y, Feng Z, Cai B, Cheng Y, Du Y, Ou S, Chen H, Pan M, Liu H, et al.

(9) Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancyGenome researchMay 15, 2024Iyer DP, Moyon L, Wittler L, Cheng CY, Ringeling FR, Canzar S, Marsico A, Bulut-Karslioğlu A.penicillin/streptomycin (Life Technologies 15140148), 1× sodium pyruvate, 25 ng/µL FGF4 (R&D Systems 235-F4-025), and 1 µg/mL heparin (Sigma-Aldrich H3149). Cells were depleted off feeders before collecting for analysis. Developmental

(10) Ligand bias underlies differential signaling of multiple FGFs via FGFR1eLifeApril 3, 2024Karl K, Del Piccolo N, Light T, Roy T, Dudeja P, Ursachi VC, Fafilek B, Krejci P, Hristova K.and replaced with DMEM without fetal bovine serum. Varying amounts of ligands (R&D Systems; FGF4, #235-F4-025; FGF8, #423-F8-025, and FGF9, # 273-F9-025) were added to each well to create a ligand concentration

(11) Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the HindgutbioRxiv : the preprint server for biologyMarch 6, 2024Qu N, Daoud A, Kechele DO, Múnera JO.

(12) A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT)Science advancesFebruary 16, 2024Hanaoka K, Ikeno T, Iwaki S, Deguchi S, Takayama K, Mizuguchi H, Tao F, Kojima N, Ohno H, Sasaki E, et al.

(13) Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in the mousebioRxiv : the preprint server for biologyJanuary 24, 2024Kruger RE, Frum T, Brumm AS, Hickey SL, Niakan KK, Aziz F, Shammami MA, Roberts JG, Ralston A.

(14) WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine ProductionCellular and molecular gastroenterology and hepatologyJanuary 1, 2024O'Connell AE, Raveenthiraraj S, Oliveira LFS, Adegboye C, Dasuri VS, Qi W, Khetani RS, Singh A, Sundaram N, Lin J, et al.

(15) Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colonCell stem cellNovember 2, 2023Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, et al.

(16) Modulation of Reoviral Cytolysis (II): Cellular StemnessVirusesJune 29, 2023Bourhill T, Rohani L, Kumar M, Bose P, Rancourt D, Johnston RN.

(17) pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cellseLifeMay 22, 2023Farahani PE, Yang X, Mesev EV, Fomby KA, Brumbaugh-Reed EH, Bashor CJ, Nelson CM, Toettcher JE.protein",Epigen,R&D Systems,Cat # 6629-EP-025, "Peptide, recombinant protein",FGF4,R&D Systems,Cat # 235-F4-025, "Peptide, recombinant protein",PDGF-BB,Millipore Sigma,Cat # P3201, "Peptide, recombinant protein",VEGF-C,R&D Systems

(18) Dynamic antagonism between key repressive pathways maintains the placental epigenomeNature cell biologyApril 1, 2023Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, et al.

(19) Controlling human organoid symmetry breaking reveals signaling gradients drive segmentation clock wavesCellFebruary 1, 2023Yusuf Ilker Yaman, Sharad RamanathanLDN 193189 dihydrochloride,R and D Systems,6053/10 Penicillin-Streptomycin,Millipore,P4458 rhFGF4,R and D Systems,235-F4–025 "DMEM/F-12, HEPES, no phenol red",Thermo Fisher Scientific,11039021 GlutaMAX™ Supplement,Thermo Fisher Scientific

(20) Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloidsDevelopment (Cambridge, England)October 15, 2022López-Anguita N, Gassaloglu SI, Stötzel M, Bolondi A, Conkar D, Typou M, Buschow R, Veenvliet JV, Bulut-Karslioglu A.(Thermo Fisher Scientific, 11360070), 1.3× β-mercaptoethanol, 1× penicillin/streptomycin, 25 ng/ml FGF4 (R&D Systems, 235-F4-025) and 1 µg/ml heparin (Sigma-Aldrich, H3149). XEN cell culture media DMEM+GlutaMAX (Gibco, 10566016)

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Recombinant Human FGF-4 Protein

FGF-4 Protein

FGF-4 Protein

FGF-4 Protein

FGF-4 Protein

Recombinant Human FGF-4 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human FGF-4 Protein from R&D Systems, a Bio-Techne Brand

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