Recombinant Human TGF-beta 2 Protein 302-B2-002 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TGF-beta 2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $438.00Supplier Page View Company Product Page
Catalog Number302-B2-002
SpeciesHuman
Size2 ug (also 10 ug)
Molecule NameTGF-beta 2
NCBI Full Gene Nametransforming growth factor beta 2
NCBI Gene AliasesLDS4, G-TSF, TGF-beta2
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 12 kDa, reducing conditions 24 kDa, non-reducing conditions
Theoretical: 12.7 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human TGF-beta 2 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Ligand-specific regulation of a binary enhancer code dictating cellular senescenceProceedings of the National Academy of Sciences of the United States of AmericaJune 17, 2025Suter T, Friedman MJ, Tazearslan C, Merkurjev D, Ohgi K, Meluzzi D, Rosenfeld MG, Suh Y.

(2) Hepatic stellate cells control liver zonation, size and functions via R-spondin 3NatureMarch 12, 2025Atsushi Sugimoto, Yoshinobu Saito, Guanxiong Wang, Qiuyan Sun, Chuan Yin, Ki Hong Lee, Yana Geng, Presha Rajbhandari, Celine Hernandez, Marcella Steffani, et al.overnight and treated with TGFβ1 (2.5 ng ml−1, R&D systems, 240B), TGFβ2 (2.5 ng ml−1, R&D systems, 302-B2-002), TGFβ3 (2.5 ng ml−1, R&D systems, 8420-B3-005), PDGF-BB (20 ng ml−1, R&D systems, 220BB) or IL-1β (5

(3) TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyesbioRxiv : the preprint server for biologyNovember 7, 2024Rudzitis CN, Lakk M, Singh A, Redmon SN, Kirdajova D, Tseng YT, De Ieso ML, Stamer WD, Herberg S, Križaj D.

(4) Targeting benign prostate hyperplasia treatments: AR/TGF-β/NOX4 inhibition by apocynin suppresses inflammation and proliferationJournal of advanced researchMarch 1, 2024Jin BR, Kim HJ, Na JH, Lee WK, An HJ.

(5) Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signalingbioRxiv : the preprint server for biologyAugust 29, 2023Choi AS, Jenkins-Lane LM, Barton W, Kumari A, Lancaster C, Raulerson C, Ji H, Altomare D, Starr MD, Whitaker R, et al.

(6) Identification of ligand-receptor pairs that drive human astrocyte developmentNature neuroscienceAugust 1, 2023Voss AJ, Lanjewar SN, Sampson MM, King A, Hill EJ, Sing A, Sojka C, Bhatia TN, Spangle JM, Sloan SA.Ligands were added in the following concentrations (Supplemental Table 3): TGFβ2 (R&D Systems, Cat. 302-B2–002, 20 ng/uL), NLGN1 (Sino Biological, Cat. 11617-H08H-100, R&D Systems, Cat. AF4340, 300 ng/uL), TSLP

(7) A ROCK inhibitor suppresses the transforming growth factor-beta-2-induced endothelial-mesenchymal transition in Schlemm's canal endothelial cellsScientific reportsJune 14, 2023Fujimoto T, Inoue-Mochita M, Inoue T.

(8) Klotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epitheliumCell death & diseaseMay 20, 2023Jang HY, Kim SJ, Park KS, Kim JH.

(9) FGF-2 Differentially Regulates Lens Epithelial Cell Behaviour during TGF-β-Induced EMTCellsMarch 7, 2023Mary Flokis, Frank J. Lovicumaintained in a humidified incubator (37 °C, 5% CO2). Different doses of recombinant human TGF-β2 (302-B2-002, R&D systems, Minneapolis, MN, USA) were used to induce EMT in the lens explants, as previously described

(10) Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 modelsProceedings of the National Academy of Sciences of the United States of AmericaJanuary 17, 2023Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, Hashimoto R, Shigesada N, Takahashi J, Tachibana M, et al.

(11) NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial CellsCellsJanuary 4, 2023Han H, Yang Y, Han Z, Wang L, Dong L, Qi H, Liu B, Tian J, Vanhaesebroeck B, Kazlauskas A, et al.

(12) High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosisScientific reportsOctober 8, 2022Kramer B, Corallo C, van den Heuvel A, Crawford J, Olivier T, Elstak E, Giordano N, Vulto P, Lanz HL, Janssen RAJ, et al.

(13) TGF-β-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial CellsInvestigative ophthalmology & visual scienceOctober 3, 2022Santerre K, Cortez Ghio S, Proulx S.

(14) MiR-18a-5p Targets Connective Tissue Growth Factor Expression and Inhibits Transforming Growth Factor β2-Induced Trabecular Meshwork Cell ContractilityGenesAugust 22, 2022Knox J, Bou-Gharios G, Hamill KJ, Willoughby CE.

(15) Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-β2Scientific reportsJune 10, 2022Callaghan B, Lester K, Lane B, Fan X, Goljanek-Whysall K, Simpson DA, Sheridan C, Willoughby CE.

(16) The compound LG283 inhibits bleomycin-induced skin fibrosis via antagonizing TGF-β signalingArthritis research & therapyApril 29, 2022Utsunomiya A, Chino T, Kasamatsu H, Hasegawa T, Utsunomiya N, Luong VH, Matsushita T, Sasaki Y, Ogura D, Niwa SI, et al.

(17) Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal TransitionInternational journal of molecular sciencesFebruary 13, 2022Sobierajska K, Wawro ME, Niewiarowska J.

(18) A20 Attenuates the Fibrotic Response in the Trabecular MeshworkInternational Journal of Molecular SciencesFebruary 9, 2022Philip Mzyk, Emma G. Zalog, Colleen M. McDowellremoved and replaced with fresh serum-free media, and cells were then treated with either TGFβ2 (5 ng/mL, 302-B2-002, Novus, Centennial, CO, USA), LPS (100 ng/mL, L3024-5MG, Sigma, St. Louis, MO, USA), or cFN-EDA (10

(19) miR-218-5p Induces Interleukin-1β and Endovascular Trophoblast Differentiation by Targeting the Transforming Growth Factor β-SMAD2 PathwayFrontiers in endocrinologyJanuary 1, 2022Shan Y, Chen Y, Brkić J, Fournier L, Ma H, Peng C.experiments, cells were also treated with recombinant human IL1β (208-IL-010), TGFβ1 (243-B-002), TGFβ2 (302-B2-002), TGFβ3 (243-B3-002), or Activin A (338-AC-010) (all purchased from R&D Systems, Minneapolis, MN, USA)

(20) Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFβ2 Induced Primary Open Angle GlaucomaInternational journal of molecular sciencesNovember 19, 2021Kasetti RB, Maddineni P, Kodati B, Nagarajan B, Yacoub S.

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Recombinant Human TGF-beta 2 Protein

TGF-beta 2 Protein

TGF-beta 2 Protein

TGF-beta 2 Protein

TGF-beta 2 Protein

Recombinant Human TGF-beta 2 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human TGF-beta 2 Protein from R&D Systems, a Bio-Techne Brand

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