Recombinant Human Thrombopoietin Protein, CF 288-TP-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Thrombopoietin Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $392.00Supplier Page View Company Product Page
Catalog Number288-TP-005/CF
SpeciesHuman
Molecule NameThrombopoietin/Tpo
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human Thrombopoietin Protein, CF
Size5 ug (also 25 ug, 200 ug, 1 mg)
NCBI Full Gene Namethrombopoietin
NCBI Gene AliasesMPLLG, TPO, ML, MGDF, MKCSF, THCYT1
Purity>97%, by SDS-PAGE with silver staining
Molecular WeightObserved: 43-60 kDa, reducing conditions
Theoretical: 35 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cellsCell reportsMarch 28, 2023Li S, Wang CS, Montel-Hagen A, Chen HC, Lopez S, Zhou O, Dai K, Tsai S, Satyadi W, Botero C, et al.

(2) IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemiaEMBO molecular medicineJanuary 11, 2023Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, Asada S, Fujino T, Fukushima T, Yonezawa T, et al.

(3) DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cellsScience advancesAugust 26, 2022Michaels YS, Edgar JM, Major MC, Castle EL, Zimmerman C, Yin T, Hagner A, Lau C, Hsu HH, Ibañez-Rios MI, et al.

(4) A topological refactoring design strategy yields highly stable granulopoietic proteinsNature communicationsMay 26, 2022Skokowa J, Hernandez Alvarez B, Coles M, Ritter M, Nasri M, Haaf J, Aghaallaei N, Xu Y, Mir P, Krahl AC, et al.

(5) MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesisCell reportsMay 10, 2022Hayashi Y, Kawabata KC, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, Nishiyama A, Kiryu S, Yoshioka Y, Ota Y, et al.

(6) Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromesNature medicineOctober 1, 2021Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, et al.

(7) A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cellsCell reportsAugust 24, 2021Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, Takeda R, Tsuchiya A, Fukuyama T, Tanaka Y, et al.

(8) Base editing of haematopoietic stem cells rescues sickle cell disease in miceNatureJuly 1, 2021Newby GA, Yen JS, Woodard KJ, Mayuranathan T, Lazzarotto CR, Li Y, Sheppard-Tillman H, Porter SN, Yao Y, Mayberry K, et al.

(9) Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell modelStem cell reportsJune 8, 2021Borst S, Nations CC, Klein JG, Pavani G, Maguire JA, Camire RM, Drazer MW, Godley LA, French DL, Poncz M, et al.

(10) Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targetsCell stem cellJune 3, 2021Wang T, Pine AR, Kotini AG, Yuan H, Zamparo L, Starczynowski DT, Leslie C, Papapetrou EP.

(11) Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndromeStem cell researchMay 1, 2021Kato H, Maezawa Y, Ouchi Y, Takayama N, Sone M, Sone K, Takada-Watanabe A, Tsujimura K, Koshizaka M, Nagasawa S, et al.

(12) Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patientsCell reports. MedicineFebruary 16, 2021Aslostovar L, Boyd AL, Benoit YD, Di Lu J, Garcia Rodriguez JL, Nakanishi M, Porras DP, Reid JC, Mitchell RR, Leber B, et al.kinase 3 ligand,R&D Systems,Cat#308-Fk/CF Recombinant human Thrombopietin protein,R&D Systems,Cat#288-TP-005/CF RPMI 1640 Medium,GIBCO,Cat#11875119 Fetal Bovine Serum,HyClone,Cat# SH3039603 Stemspan,Stem Cell Technologies

(13) UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 ComplexCell stem cellJanuary 7, 2021Chagraoui J, Girard S, Spinella JF, Simon L, Bonneil E, Mayotte N, MacRae T, Coulombe-Huntington J, Bertomeu T, Moison C, et al.

(14) A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and OrganoidsCell stem cellJuly 2, 2020Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, et al.

(15) Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem CellsCell reportsJune 2, 2020Wesely J, Kotini AG, Izzo F, Luo H, Yuan H, Sun J, Georgomanoli M, Zviran A, Deslauriers AG, Dusaj N, et al.

(16) Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signallingJournal of cellular and molecular medicineJune 1, 2020Zou Z, Fan X, Liu Y, Sun Y, Zhang X, Sun G, Li X, Xu S.Recombinant human EGF and recombinant human TPO were purchased from PeproTech (AF‐100‐15‐100) and R&D Systems (288‐TP‐005/CF), respectively. 2.13 Statistical analysis SPSS 17.0 software (SPSS, Inc) and GraphPad Prism 6.0 software

(17) Generation and characterization of HLA-universal platelets derived from induced pluripotent stem cellsScientific reportsMay 21, 2020Norbnop P, Ingrungruanglert P, Israsena N, Suphapeetiporn K, Shotelersuk V.

(18) CRISPR/Cas9-mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patientsHaematologicaMarch 1, 2020Nasri M, Ritter M, Mir P, Dannenmann B, Aghaallaei N, Amend D, Makaryan V, Xu Y, Fletcher B, Bernhard R, et al.

(19) Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia veraPloS oneJanuary 1, 2020Spivak JL, Merchant A, Williams DM, Rogers O, Zhao W, Duffield A, Resar LS, Moliterno AR, Zhao ZJ.

(20) Discrimination of Dormant and Active Hematopoietic Stem Cells by G₀ Marker Reveals Dormancy Regulation by Cytoplasmic CalciumCell reportsDecember 17, 2019Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, et al.

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Recombinant Human Thrombopoietin Protein, CF

Thrombopoietin/Tpo Protein

Thrombopoietin/Tpo Protein

Thrombopoietin/Tpo Protein

Thrombopoietin/Tpo Protein

Recombinant Human Thrombopoietin Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human Thrombopoietin Protein, CF from R&D Systems, a Bio-Techne Brand

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