Recombinant Human R-Spondin 3 Protein, CF 3500-RS-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human R-Spondin 3 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $408.00Supplier Page View Company Product Page
Catalog Number3500-RS-025/CF
SpeciesHuman
Molecule NameR-Spondin 3
NCBI Full Gene NameR-spondin 3
NCBI Gene AliasesTHSD2, CRISTIN1, PWTSR
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemCHO-derived Recombinant Human R-Spondin 3 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Molecular WeightObserved: 36-45 kDa, reducing conditions
Theoretical: 28.3 kDa
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Size25 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Feasibility of Manufacturing and Antitumor Activity of TIL for Advanced Endometrial CancersInternational Journal of Molecular SciencesJuly 24, 2025Yongliang Zhang, Kathleen N. Moore, Amir A. Jazaeri, Judy Fang, Ilabahen Patel, Andrew Yuhas, Patrick Innamarato, Nathan Gilbert, Joseph W. Dean, Behzad Damirchi, et al.mM,Sigma Aldrich,73240-100G Noggin,10 ng/mL,Peprotech,120-10C RH R-Spondin 3,25 ng/mL,R&D Systems,3500-RS-025/CF SB202190,100 nM,Sigma Aldrich,S7067-5MG Y-27632,10 µM,"Selleckchem (Houston, TX, USA)",S1049 Anti-Anti

(2) R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeletoneLifeNovember 2, 2022Nagano K, Yamana K, Saito H, Kiviranta R, Pedroni AC, Raval D, Niehrs C, Gori F, Baron R.

(3) The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genesJournal of cell scienceOctober 1, 2022Pizzolato G, Moparthi L, Söderholm S, Cantù C, Koch S.

(4) Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoidsNature protocolsApril 1, 2021Dekkers JF, van Vliet EJ, Sachs N, Rosenbluth JM, Kopper O, Rebel HG, Wehrens EJ, Piani C, Visvader JE, Verissimo CS, et al.

(5) Development of a human primary gut-on-a-chip to model inflammatory processesScientific reportsDecember 8, 2020Beaurivage C, Kanapeckaite A, Loomans C, Erdmann KS, Stallen J, Janssen RAJ.

(6) RSPO3 impacts body fat distribution and regulates adipose cell biology in vitroNature communicationsJune 3, 2020Loh NY, Minchin JEN, Pinnick KE, Verma M, Todorčević M, Denton N, Moustafa JE, Kemp JP, Gregson CL, Evans DM, et al.

(7) Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organsPloS oneJanuary 1, 2020Zhang M, Haughey M, Wang NY, Blease K, Kapoun AM, Couto S, Belka I, Hoey T, Groza M, Hartke J, et al.

(8) Breast cancer organoids from a patient with giant papillary carcinoma as a high-fidelity modelCancer cell internationalJanuary 1, 2020Li X, Pan B, Song X, Li N, Zhao D, Li M, Zhao Z.

(9) A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansionNature communicationsDecember 2, 2019Boone PG, Rochelle LK, Ginzel JD, Lubkov V, Roberts WL, Nicholls PJ, Bock C, Flowers ML, von Furstenberg RJ, Stripp BR, et al.

(10) Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signalingThe Journal of biological chemistryJune 22, 2018Park S, Cui J, Yu W, Wu L, Carmon KS, Liu QJ.

(11) R-spondins can potentiate WNT signaling without LGRseLifeFebruary 6, 2018Lebensohn AM, Rohatgi R.

(12) Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer TypesCancer researchFebruary 1, 2016Chartier C, Raval J, Axelrod F, Bond C, Cain J, Dee-Hoskins C, Ma S, Fischer MM, Shah J, Wei J, et al.

(13) Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor CellsPloS oneJanuary 1, 2016Zeve D, Millay DP, Seo J, Graff JM.

(14) RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signalingProceedings of the National Academy of Sciences of the United States of AmericaApril 1, 2014Carmon KS, Gong X, Yi J, Thomas A, Liu Q.

(15) RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancerNature communicationsJanuary 1, 2014Wu C, Qiu S, Lu L, Zou J, Li WF, Wang O, Zhao H, Wang H, Tang J, Chen L, et al.

(16) Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondinEMBO reportsDecember 1, 2013Xie Y, Zamponi R, Charlat O, Ramones M, Swalley S, Jiang X, Rivera D, Tschantz W, Lu B, Quinn L, et al.

(17) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(18) ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerNatureApril 29, 2012Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, et al.

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Recombinant Human R-Spondin 3 Protein, CF

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R-Spondin 3 Protein

Recombinant Human R-Spondin 3 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human R-Spondin 3 Protein, CF from R&D Systems, a Bio-Techne Brand

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