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N,N-Dimethylsphingosine (d18:1)
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N,N-Dimethylsphingosine (d18:1)
N,N-Dimethylsphingosine (d18:1)
N,N-Dimethylsphingosine (d18:1) from Cayman Chemical
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Citations:
(3)
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N,N-Dimethylsphingosine (d18:1)
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Description
An SPHK inhibitor (Kis = 3.1, 6.8, and 2.3 µM in U937, PC12, and Swiss 3T3 cell extracts, respectively); selective for SPHK over PKC in PC12 cells at 10 µM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
N,N-Dimethylsphingosine (d18:1)
Company
Cayman Chemical
Price
$455.00
Supplier Page
View Company Product Page
Catalog Number
62575
Size
50 mg
Format
A 25 mg/ml solution in ethanol
Molecular Weight
327.6
Purity
≥98%
Type
Inhibitors
Research Area
Lipid Biochemistry, Sphingolipids
Storage
-20
Formula
C20H41NO2
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell-Type Dependent and Tied to Ceramide Homeostasis
FASEB J
March 31, 2026
Michal Mrkacek, Magda Tumova, Alex Puskasu, Pavol Utekal, Marek Vrbacky, Ladislav Kuchar, Petr Draber, Viktor Bugajev
chloroquine (CQ; Cat#
C6628
) or MG132 (Cat# M8699) from
Sigma‐Aldrich
; N,N‐dimethylsphingosine (N,N‐DMS; Cat#
62575
) or dimethyloxallyl glycine (
DMOG
; Cat#
71210
) from
Cayman Chemical
, Ann Arbor, MI, USA; or
CB‐5083
(2)
Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation
Journal of Virology
May 11, 2022
Rachel S. Resop, Alberto Bosque
ABC294640
were obtained from
Cayman Chemical
(
FTY720
, number
10006292
, CAS number 162359-56-0; DMS, number
62575
, CAS number 119567-63-4; SKI II, number
10009222
, CAS number 312636-16-1;
ABC294640
, number
10587
, CAS
(3)
Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response
International Journal of Molecular Medicine
September 29, 2017
Wei Sun, Zhaoming Ding, Shengjie Xu, Zhiqiang Su, Hulun Li
IL-17, IL-1, TNF-α, no. 870257) were purchased from LightArray Biotech Co. (Shanghai, China); and DMS (
62575
) was purchased from
Cayman Chemical
(Ann Arbor, MI, USA). Establishment of focal cerebral I/R model.
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N,N-Dimethylsphingosine (d18:1) from Cayman Chemical
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$455.00
Product Specs
Company Info
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