Recombinant Human LRP-1 Cluster II Fc Chimera Protein, CF 2368-L2-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human LRP-1 Cluster II Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $523.00Supplier Page View Company Product Page
Catalog Number2368-L2-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameLRP-1 Cluster II
Size50 ug
NCBI Full Gene NameLDL receptor related protein 1
NCBI Gene AliasesLRP1A, APOER, TGFBR5, LRP, APR, A2MR, IGFBP-3R, CD91, IGFBP3R, KPA, IGFBP3R1
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 90-100 kDa, reducing conditions
Theoretical: 68.1 kDa
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human LRP-1 Cluster II Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorptionThe Journal of cell biologyApril 3, 2023Zhu L, Tang Y, Li XY, Kerk SA, Lyssiotis CA, Sun X, Wang Z, Cho JS, Ma J, Weiss SJ.LRP-1 Cluster II Fc Chimera Protein covering ∼10% of the full-length Lpr1 protein sequence, including 3 N-glycosylation sites (#2368-L2-050; R&D Systems) at 0.5 μg in 100 μl PBS, incubated at 4°C overnight, and blocked with 50 mg/ml BSA for

(2) Generation of KS-487 as a novel LRP1-binding cyclic peptide with higher affinity, higher stability and BBB permeabilityBiochemistry and biophysics reportsDecember 1, 2022Sakamoto K.

(3) Lrp1 is a host entry factor for Rift Valley fever virusCellSeptember 30, 2021Safder S. Ganaie et al.CLIV-Fc Chimera (R&D SYSTEMS, #5395-L4–050), recombinant human LRP-1 CLII-Fc chimera (R&D SYSTEMS, #2368-L2–050), or recombinant human IgG1 Fc (R&D SYSTEMS, #110-HG-100) were loaded at 200 nM in buffer for 600s prior

(4) A novel peptide ligand RAP12 of LRP1 for glioma targeted drug deliveryJournal of controlled release : official journal of the Controlled Release SocietyJune 10, 2018Ruan H, Chai Z, Shen Q, Chen X, Su B, Xie C, Zhan C, Yao S, Wang H, Zhang M, et al.

(5) A novel LRP1-binding peptide L57 that crosses the blood brain barrierBiochemistry and biophysics reportsDecember 1, 2017Sakamoto K, Shinohara T, Adachi Y, Asami T, Ohtaki T.

(6) Low-Density Lipoprotein Receptor-Related Protein-1 Is a Therapeutic Target in Acute Myocardial InfarctionJACC. Basic to translational scienceOctober 1, 2017Toldo S, Austin D, Mauro AG, Mezzaroma E, Van Tassell BW, Marchetti C, Carbone S, Mogelsvang S, Gelber C, Abbate A.

(7) Evidence That Factor VIII Forms a Bivalent Complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): IDENTIFICATION OF CLUSTER IV ON LRP1 AS THE MAJOR BINDING SITEThe Journal of biological chemistryDecember 9, 2016Young PA, Migliorini M, Strickland DK.

(8) Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activitiesPloS oneJanuary 1, 2014Thevenard J, Verzeaux L, Devy J, Etique N, Jeanne A, Schneider C, Hachet C, Ferracci G, David M, Martiny L, et al.

(9) A small molecule inhibitor to plasminogen activator inhibitor 1 inhibits macrophage migrationArteriosclerosis, thrombosis, and vascular biologyMay 1, 2013Ichimura A, Matsumoto S, Suzuki S, Dan T, Yamaki S, Sato Y, Kiyomoto H, Ishii N, Okada K, Matsuo O, et al.

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Recombinant Human LRP-1 Cluster II Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human LRP-1 Cluster II Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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