Recombinant Mouse IL-1α (carrier-free) 575002 from BioLegend

Product Specs
ItemRecombinant Mouse IL-1α (carrier-free)
CompanyBioLegend
Price $206.00Supplier Page View Company Product Page
Catalog Number575002
Format0.22 µm filtered protein solution is in 10 mM Sodium Phosphate buffer, 150 mM NaCl, pH 7.2
Size10 µg
ApplicationsBioassay
Gene Nameinterleukin 1 alpha
NCBI Gene AliasesIl-1a
NCBI Full Gene Nameinterleukin 1 alpha
Molecule NameIL-1alpha
Concentration10 and 25 µg sizes are bottled at 200 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool
SpeciesMouse

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) In vivo detection of immune responses via cytokine activity labelingCellFebruary 5, 2026Guangqing Lu, Shanshan Zhang, Mengyang Feng, Eunha Kim, Daniel Cho, Jae Hyun Kim, Hannah Caris, Lev Silberstein, Gloria B. Choi, Jun R. HuhRecombinant Mouse IFN-γ (carrier-free),BioLegend,Cat# 575308 Recombinant Mouse IL 1α (carrier free),BioLegend,Cat# 575002 Recombinant Mouse IL-1β (carrier-free),BioLegend,Cat# 575102 Recombinant Mouse IL-4 (carrier-free),BioLegend,Cat#

(2) Type 2 diabetes mellitus exacerbates vaginal group B Streptococcus colonization via impaired mucosal cytokine responsebioRxivJanuary 10, 2026Clare M. Robertson, Vicki Mercado-Evans, Addison B. Larson, Holly Branthoover, Samantha Ottinger, Marlyd E. Mejia, Zainab A. Hameed, Camille Serchejian, Libbie Ogilvie, Jacob J. Zulk, et al.experiments Mice were vaginally inoculated with 80 pg of recombinant mouse IL-1α (BioLegend, Cat. No. 575002) resuspended in 10μL sterile PBS. Mice were treated every day beginning 1 day prior to infection, with

(3) CD4 + T Cells Expressing Viral Proteins Induce HIV-Associated Endothelial Dysfunction and Hypertension Through Interleukin 1α–Mediated Increases in Endothelial NADPH Oxidase 1CirculationApril 22, 2025Taylor C. Kress, Candee T. Barris, Laszlo Kovacs, Beryl N. Khakina, Coleton R. Jordan, Thiago Bruder-Nascimento, David W. Stepp, Rodger MacArthur, Vijay S. Patel, Jie Chen, et al.(BioXcell, CAT: BE0243, 400μg/mouse, IP, every other day), or exogenous IL-1α (32ng/kg/day, Biolegend, CAT: 575004, subcutaneous Azlet mini-pump, MODEL: 1002) or submitted to CD4+ T cells depletion via intraperitoneal injections

(4) A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infectionThe EMBO JournalMarch 24, 2025Hui Wen Yeap, Ghin Ray Goh, Safwah Nasuha Rosli, Hai Shin Pung, Cristina Giogha, Vik Ven Eng, Jaclyn S Pearson, Elizabeth L Hartland, Kaiwen W ChenRecombinant Mouse TNF-α (carrier-free),BioLegend,#575206 Recombinant Mouse IFN-γ (carrier-free),BioLegend,#575306 Recombinant Mouse IL-1α (carrier-free),BioLegend,#575006 Recombinant Mouse IL-1β (carrier-free),BioLegend,#575102 TPCA,Selleck Chemicals,#S2824 5Z-7-Oxozeaenol

(5) T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFα InflammationCancer Immunology ResearchFebruary 3, 2025Nam Woo Cho, Sophia M. Guldberg, Barzin Y. Nabet, Jie Zeng Yu, Eun Ji Kim, Kamir J. Hiam-Galvez, Jacqueline L. Yee, Rachel DeBarge, Iliana Tenvooren, Naa Asheley Ashitey, et al.CXCL1 by ELISA following TNFα, IL-1α, or IL1-β stimulation, 10 ng/ml of cytokine (Biolegend 575202, 575002, 575102) was added (unless otherwise stated) to cell culture media 24 hours prior to collection of supernatant

(6) Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancerCell reportsNovember 8, 2022Millar FR, Pennycuick A, Muir M, Quintanilla A, Hari P, Freyer E, Gautier P, Meynert A, Grimes G, Coll CS, et al.above and intranasally inoculated with 100ng of carrier free recombinant protein (rIL-1α – Biolegend #575002, rIL-1β – Biolegend #575102) suspended in sterile phosphate buffered saline (PBS). For Tlr2 agonist

(7) Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injuryCell reportsMay 11, 2021Liberti DC, Kremp MM, Liberti WA 3rd, Penkala IJ, Li S, Zhou S, Morrisey EE.organoid formation (Katsura et al., 2019). Experiments involving IL-1α (10ng/mL, BioLegend, catalog # 575002), IL-1β (10ng/mL, BioLegend, catalog # 575102), TNFα (10ng/mL, BioLegend, catalog # 575202), or mFGF7

(8) Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial InflammationCell host & microbeNovember 11, 2020Liu X, Boyer MA, Holmgren AM, Shin S.Growth Factor Reduced Basement Membrane Matrix,Corning,Cat#354230 Recombinant Mouse IL-1α,BioLegend,Cat#575002 Recombinant Mouse IL-1β,BioLegend,Cat#575102 Recombinant Mouse GM-CSF,BioLegend,Cat#576304 Recombinant

(9) An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus ReplicationMolecular cellSeptember 6, 2018Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC.human TNFα,Biolegend,# 570102 Poly (I:C)-HMW,Invivogen,# tlr-pic Recombinant mouse IL-1α,Biolegend,# 575002 Recombinant mouse IL-1β,Biolegend,# 575102 Bv6,Millipore,# 533965 Pyridone 6,Millipore,# 420099 Cycloheximide,Sigma,#

(10) Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and InflammationFrontiers in immunologyJanuary 1, 2018Michaudel C, Maillet I, Fauconnier L, Quesniaux V, Chung KF, Wiegman C, Peter D, Ryffel B.injection given at 200 μg/mouse, 12 h before ozone exposure. Recombinant mouse IL-1α (rmIL-1α) (Biolegend 575004, 0.8 μg/mice) was instilled intratracheally (i.t.) 4 h after ozone exposure. Ozone-Induced Airway Inflammation We

(11) HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33ImmunityOctober 17, 2017Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM, le Bihan T, et al.Recombinant Proteins","Chemicals, Peptides, and Recombinant Proteins" ,, Recombinant mouse IL-1α,Biolegend,575002 Recombinant mouse IL-33,Biolegend,580506 Recombinant human IL-33,Biolegend,581806 ST2-Fc,Biolegend,557904 Dynabeads

(12) Effective combinatorial immunotherapy for castration-resistant prostate cancerNatureMarch 30, 2017Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, et al.(RPMI1640 supplemented with 10% FBS) with indicated concentration of recombinant mouse IL-1α (BioLegend, 575002), IL-1β (BioLegend, 575102), IL-1ra (VWR, 10006-448) or mouse IL-1ra neutralizing antibody (R&D Systems,

(13) IL-1α modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oilJournal of immunology (Baltimore, Md. : 1950)February 1, 2011Lee PY, Kumagai Y, Xu Y, Li Y, Barker T, Liu C, Sobel ES, Takeuchi O, Akira S, Satoh M, et al.

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Recombinant Mouse IL-1α (carrier-free) from BioLegend

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Recombinant Mouse IL-1α (carrier-free) from BioLegend

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