Fig 1: B. lactis BX-BC08 alleviates MC903-induced AD-like skin inflammation in BALB/c mice. (A) Schematic diagram illustrating the experimental design and timeline of the female MC903 mice model. (B) Representative ear pictures at day 14. (C) Ear thickness measurements taken from day 0 to day 14. (D) Temporal pattern of AD scores across different treatment regimens. (E) Representative ear sections were stained with H&E for the indicated groups. Scale bar = 20 x, 100 μm. The black line delineates the basement membrane. (F) Quantification of the ear epidermal thickness from panel (E). (G) Gene expression levels of IL-4, IL-13, IL-25, and TSLP in the ear from each group. (H) Measurement of serum cytokine levels (IL13, IL22 and CCL17/TRAC) in mice for the indicated treatments. All data represent two to three independent experiments and are presented as means ± S.E.M. Significant differences between groups were determined using ANOVA
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