p44/42 MAPK (Erk1/2) Control Cell Extracts from Cell Signaling Technology

Product Specs
Itemp44/42 MAPK (Erk1/2) Control Cell Extracts
CompanyCell Signaling Technology
Price $162.00 Inquire
Catalog Number9194S
SourceCell
Research AreaMAP Kinase Signaling
TypeCell Extracts
ApplicationsW
Quantity150 µl

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Sphingosine-1-phosphate promotes CD8 T cell exhaustion in breast cancer via exosomal transfer of TGFBR2Cell Death DisMarch 23, 2026Avinandan Bhoumick, Arnab Ghosh, Arpana Singh, Subhasis Mandal, Tanvi Agarwal, Rima Halder, Biswajit Das, Soma Mukhopadhyay, Prosenjit Sen(4060), anti-Pontin (12300), anti-USP8 (8728), anti-USP9X (5751), anti-p-ERK1/2 (8544), anti-ERK1/2 (9194) were purchased from Cell Signaling Technology. Anti-Alix (3A9) was purchased from Bio-Rad. Anti-BrdU

(2) Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal ToxicityFASEB BioAdvancesAugust 1, 2025Luca Sanguigno, Natascia Guida, Mariarosaria Cammarota, Silvia Ruggiero, Angelo Serani, Francesca Galasso, Vincenzo Pizzorusso, Francesca Boscia, Luigi FormisanoPA5‐114451); Anti‐NRP1 (GeneTex, GXGTX127947); Anti‐ACE2 (SantaCruz, sc‐390851); Anti‐CREB (Cell Signaling, 9194S). Anti‐HDAC4 [21]; Anti‐RIPK1; Anti‐CREB; and Anti‐Actin [26], which have been used in previous studies. 2.2

(3) Intrauterine Growth Restriction Affects Colonic Barrier Function via Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Homeostasis in Growing–Finishing PigsAntioxidants (Basel)February 26, 2024Liang Xiong, Md. Abul Kalam Azad, Yang Liu, Wanghong Zhang, Qian Zhu, Chengjun Hu, Jinming You, Xiangfeng Kong(#21773-1-AP, Proteintech), TLR4 (#14358, CST), NF-κB (#ab32536, Abcam), p-NF-κB (#3033, CST), ERK1/2 (#9194, CST), p-ERK1/2 (#4370, CST), Nrf2 (#bs-1074R, Bioss), p-Nrf2 (bs-2013R, Bioss), and Keap1 (#bs-3648R,

(4) SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca2+-mediated autophagyJournal of Dental SciencesOctober 1, 2023Xiangbin Bu, Jun Zhang, Hengyan Sun, Wenlong Wang, Xiangrui Ma, Legang Sunanti-p-ERK1/2 (1:1000, #45899, Cell Signaling Technology, Danvers, MA, USA), anti-ERK1/2 (1:1000, #9194, Cell Signaling Technology); anti-p-AMPKα (1:1000, #2535, Cell Signaling Technology), anti-AMPKα (1:1000,

(5) The inhibitory effect of isoliquiritigenin on human platelets in vitroAnnals of Translational MedicineMarch 31, 2023Yingying Wu, Cheng Deng, Yixuan Wang, Zhangyin Ming, Heng Mei, Yu Huantibody (50535, CST), anti-phospho-ERK1/2 (Thr202/Tyr204) antibody (4370, CST), anti-ERK1/2 antibody (9194, CST), anti-phospho-Jun N-terminal kinase (JNK) (Thr183/Tyr185) antibody (sc-6254, Santa Cruz), anti-JNK

(6) Modulation of viral replication, apoptosis and antiviral response by induction and mutual regulation of EGR and AP-1 family genes during coronavirus infectionEmerging Microbes & InfectionsDecember 31, 2022Lixia Yuan, To Sing Fung, Jiawen He, Rui Ai Chen, Ding Xiang Liu[19]. Antibodies, chemicals and reagents Antibodies against EGR1 (#4154), cJUN (#9165), cFOS (#2250), ERK1/2 (#9194), JNK (#9252), p38 (#9212), PARP (#9532), β-actin (#4967) were purchased from Cell Signaling Technology.

(7) A Novel Antithrombocytopenia Agent, Rhizoma cibotii, Promotes Megakaryopoiesis and Thrombopoiesis through the PI3K/AKT, MEK/ERK, and JAK2/STAT3 Signaling PathwaysInternational journal of molecular sciencesNovember 14, 2022Chen W, Zhu L, Wang L, Zeng J, Wen M, Xu X, Zou L, Huang F, Huang Q, Qin D, et al.12831S), phospho (P)- MEK1/2 (CST, 2338S)), MEK1/2 (CST, 4694S), P-ERK1/2 (CST, 9101S), ERK1/2 (CST, 9194S), P-STAT3 (CST, 9145S), STAT3 (CST, 12640S), P-PI3K (CST, 17366S), PI3K (CST, 4255S), P-AKT (CST, 4060S),

(8) Evaluation of the Cytotoxic, Anti-Inflammatory, and Immunomodulatory Effects of Withaferin A (WA) against Lipopolysaccharide (LPS)-Induced Inflammation in Immune Cells Derived from BALB/c MicePharmaceuticsJune 13, 2022Alnuqaydan AM, Almutary A, Bhat GR, Mir TA, Wani SI, Rather MY, Mir SA, Alshehri B, Alnasser S, Ali Zainy FM, et al.(#13120), p-p65 (Ser-276) (# 8242S), p-p65 (Ser-536) (#3033S), p-IkB-α (#2859S), IkB-α (# 9242S), ERK1/2 (#9194S), p-ERK1/2 (#9101S), Akt (#4885S), p-Akt (Ser473) (#4060S), Cox-2 (#4842S), and β-actin (#8457S) were

(9) Cosmc deficiency causes spontaneous autoimmunity by breaking B cell toleranceScience advancesOctober 8, 2021Zeng J, Aryal RP, Stavenhagen K, Luo C, Liu R, Wang X, Chen J, Li H, Matsumoto Y, Wang Y, et al.#4695T), lamin B (Cell Signaling Technology, #9622), and total ERK1/2 (Cell Signaling Technology, #9194). For C3 complement Western blot analysis, sera were prepared from mice and stored at −20°C until use.

(10) Stimulator of interferon response cGAMP interactor overcomes ERBB2-mediated apatinib resistance in head and neck squamous cell carcinomaAging (Albany NY)August 31, 2021Guo Ye, Junbin Zhang, Chengyao Zhang1:1,000); p-AKT (catalog number 4060S; 1:1,000); extracellular regulated kinase (ERK) (catalog number 9194S; 1:1,000); p-ERK (catalog number 4370S; 1:1,000); and GAPDH (catalog number 174S; 1:1,000). All primary

(11) Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF SignalingFrontiers in Cell and Developmental BiologyAugust 24, 2021Kaiwen Liu, Jianlu Wei, Guohua Li, Ronghan Liu, Dawang Zhao, Yuanqiang Zhang, Jie Shi, Qing Xie, Lei Chenglamin B1 (catalog#13435), anti-P38 (catalog#8690), anti-p-P38 (catalog#4511), anti-ERK1/2 (catalog#9194), anti-p-ERK1/2 (catalog#4370), anti-p-P65 (catalog#3033), and anti-P65 (catalog#8242) from Cell Signaling Technology

(12) RO4929097 regulates RANKL-induced osteoclast formation and LPS-mediated bone resorptionAging (Albany NY)May 15, 2021Tao Huang, Congyun Zhao, Yi Zhao, Yuan Zhou, Lei Wang, Donghua HangCell Signaling Technology, Inc.); p-ERK (cat no.4370S; 1:1,000; Cell Signaling Technology, Inc.); Erk (cat no.9194S; 1:1,000; Cell Signaling Technology, Inc.); p65 (cat no.8242S; 1:1,000; Cell Signaling Technology, Inc.); p-p38

(13) HMGB1 knockdown increases the radiosensitivity of esophageal squamous cell carcinoma by regulating the expression of molecules involved in DNA repairOncology LettersApril 29, 2021Guohu Han, Rui Ling, Changchun Sun, Xuefeng Wang, Yuepeng Zhou, Lijiang Yu, Shenzha Liuantibodies were diluted in PBS at 1:500 and purchased from Cell Signaling Technology, Inc.: ERK1/2 (cat. no. 9194S), p-ERK1/2 (cat. no. 4370T), JNK (cat. no. 9252S), p-JNK (cat. no. 9251S), p38 (cat. no. 9212S), p-p38

(14) NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangiomaJCI insightFebruary 8, 2021Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR.(catalog 2527), phospho-RB1 (catalog 8516), RB1 (catalog 9313), HSP90 (catalog 4877), p44/42MAPK (catalog 9194), phospho-p44/42MAPK (catalog 8544), pan-cadherin (catalog 4068), p38MAPK (catalog 9212), phospho-p38MAPK

(15) Eif2s3y Promotes the Proliferation of Spermatogonial Stem Cells by Activating ERK SignalingStem cells internationalJanuary 1, 2021Zhang M, Li N, Liu W, Du X, Wei Y, Yang D, Zhou Z, Ma F, Peng S, Zhang S, et al.BBI Life, Shanghai, China), anti-pERK (1 : 2000; #4370, CST, Boston, USA), and anti-ERK (1 : 2000; #9194, CST, Boston, USA). The results were detected using a Bio-Rad imaging system (Bio-Rad, Hercules, CA,

(16) Pharmacologic Inhibition of FGFR Modulates the Metastatic Immune Microenvironment and Promotes Response to Immune Checkpoint BlockadeCancer immunology researchDecember 1, 2020Akhand SS, Liu Z, Purdy SC, Abdullah A, Lin H, Cresswell GM, Ratliff TL, Wendt M.lysates were probed with antibodies for phospho-ERK1/2 (#4370), phospho-Akt (#4070) and total ERK1/2 (#9194) (all antibodies Cell Signaling Technologies). Immune cell killing assays The impact of FIIN4 on the

(17) Hyperactivity of Mek in TNS1 knockouts leads to potential treatments for cystic kidney diseasesCell Death & DiseaseDecember 1, 2019Zong-Ye Wu, Chun-Lung Chiu, Ethan Lo, Yuh-Ru Julie Lee, Soichiro Yamada, Su Hao LopMEK1/2(S221) (#2338), pMEK1/2(S217/221) (#9154), Mek1/2 (#9122), pERK1/2(T202Y204) (#9101), ERK1/2 (#9194), pAkt(S473) (#9271), Akt (#9272), pGSK3β(S9) (#5558), and GSK3β (#12456) were from Cell Signaling Technology.

(18) Anti‑inflammatory effects of Dendropanax�morbifera in lipopolysaccharide‑stimulated RAW264.7 macrophages and in an animal model of atopic dermatitisMolecular Medicine ReportsJanuary 22, 2019Gang‑Sik Choo, Dong‑Pyo Lim, Sae‑Man Kim, Eun‑Seon Yoo, Sung‑Hyun Kim, Chang‑Hyun Kim, Joong‑Seok Woo, Hyeong‑Jin Kim, Ji‑Youn Junginhibitor-α (IκB-α; cat. no. 4812), IκB-α (cat. no. 5209) p-ERK1/2 (cat. no. 4376), ERK1/2 (cat. no. 9194), p-P38 MAPK (cat. no. 9211), P38 MAPK (cat. no. 8690), p-JNK (cat. no. 4668), JNK (cat. no. 9252) and

(19) PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasionJournal of Experimental & Clinical Cancer ResearchDecember 1, 2018Xiupeng Xu, Zhongyuan Bao, Yinlong Liu, Kuan Jiang, Tongle Zhi, Dong Wang, Liang Fan, Ning Liu, Jing Ji(1:500, no. 9145), MEK1/2 (1:1500, no. 4694), phospho-MEK1/2 (1:1000, no. 4370), ERK1/2 (1:2000, no. 9194,) and phospho-ERK1/2 (1:1000, no. 4370) all from Cell Signaling Technologies (Danvers, MA, USA). In vitro

(20) Activated protein C inhibits lung injury induced by LPS via downregulating MAPK signalingExperimental and Therapeutic MedicineMay 29, 2018Jianming Zhou, Ruoyu Hu, Shengjie Jing, Xin Xue, Wenhao Tangmilk, blots were incubated with specific antibodies (p38 (catalogue no.: 8690), p‑p38 (4511), ERK1/2 (9194), p‑ERK1/2 (9101), c‑Jun N‑terminal kinase (JNK) (9252), and p‑JNK(9255)) purchased from Cell Signaling Technology

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