Recombinant Human/Mouse/Rat GDF-8/Myostatin Protein, CF 788-G8-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human/Mouse/Rat GDF-8/Myostatin Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $428.00Supplier Page View Company Product Page
Catalog Number788-G8-010/CF
SpeciesHuman, Mouse, Rat
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Size10 ug (also 100 ug, 250 ug)
Molecule NameGDF-8/Myostatin
NCBI Full Gene Namemyostatin
NCBI Gene AliasesGdf8, GDF8, Cmpt, MSLHP
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 12 kDa, reducing conditions 24 kDa, non-reducing conditions
Theoretical: 12.4 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human/Mouse/Rat GDF-8/Myostatin Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Biomechanical Stimulation of Muscle Constructs Influences Phenotype of Bone Constructs by Modulating Myokine SecretionJBMR PlusNovember 1, 2023Harshini Suresh Kumar, Edwina N. Barnett, John L. Fowlkes, Evangelia Kalaitzoglou, Ramkumar T. Annamalaiin tissue culture plates were differentiated for 5 days and treated with myostatin at 100 ng/mL of media (788‐G8‐010/CF R&D Systems), follistatin at 100 ng/mL of media (769‐FS‐025/CF, R&D Systems), and a cocktail of myostatin

(2) A New Method of Myostatin Inhibition in Mice via Oral Administration of Lactobacillus casei Expressing Modified Myostatin Protein, BLS-M22International journal of molecular sciencesAugust 13, 2022Sung DK, Kim H, Park SE, Lee J, Kim JA, Park YC, Jeon HB, Chang JW, Lee J.

(3) Maternal immunization against myostatin suppresses post-hatch chicken growthPloS oneJanuary 1, 2022Mishra R, Jha R, Mishra B, Kim YS.

(4) The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatinArchives of biochemistry and biophysicsOctober 15, 2020Chang YC, Liu HW, Chan YC, Hu SH, Liu MY, Chang SJ.

(5) Myostatin Inhibits Vascular Smooth Muscle Cell Proliferation and Local 14q32 microRNA Expression, But Not Systemic Inflammation or RestenosisInternational journal of molecular sciencesMay 15, 2020Goossens EAC, de Vries MR, Jukema JW, Quax PHA, Nossent AY.

(6) Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015The Journal of biological chemistryApril 17, 2020Dagbay KB, Treece E, Streich FC Jr, Jackson JW, Faucette RR, Nikiforov A, Lin SC, Boston CJ, Nicholls SB, Capili AD, et al.

(7) Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cellsPloS oneJanuary 1, 2020Kodaka M, Mao F, Arimoto-Matsuzaki K, Kitamura M, Xu X, Yang Z, Nakagawa K, Maruyama J, Ishii K, Akazawa C, et al.

(8) TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle MassFrontiers in physiologyJanuary 1, 2020Hagg A, Kharoud S, Goodchild G, Goodman CA, Chen JL, Thomson RE, Qian H, Gregorevic P, Harrison CA, Walton KL.

(9) AdipoRon prevents myostatin-induced upregulation of fatty acid synthesis and downregulation of insulin activity in a mouse hepatocyte linePhysiological reportsAugust 1, 2019Liu XH, Pan JP, Bauman WA, Cardozo CP.

(10) A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx miceSkeletal muscleMay 27, 2019Jin Q, Qiao C, Li J, Xiao B, Li J, Xiao X.

(11) GDF8 enhances SOX2 expression and blastocyst total cell number in porcine IVF embryo developmentTheriogenologyApril 15, 2019Yoon JD, Hwang SU, Kim M, Lee G, Jeon Y, Hyun SH.

(12) Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animalsPloS oneJanuary 1, 2019Kim JH, Kim JH, Sutikno LA, Lee SB, Jin DH, Hong YK, Kim YS, Jin HJ.

(13) Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade aloneSkeletal muscleOctober 27, 2018Iskenderian A, Liu N, Deng Q, Huang Y, Shen C, Palmieri K, Crooker R, Lundberg D, Kastrapeli N, Pescatore B, et al.

(14) Biological scaffold-mediated delivery of myostatin inhibitor promotes a regenerative immune response in an animal model of Duchenne muscular dystrophyThe Journal of biological chemistryOctober 5, 2018Estrellas KM, Chung L, Cheu LA, Sadtler K, Majumdar S, Mula J, Wolf MT, Elisseeff JH, Wagner KR.

(15) JNK regulates muscle remodeling via myostatin/SMAD inhibitionNature communicationsAugust 2, 2018Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ.

(16) Relative abundance of mature myostatin rather than total myostatin is negatively associated with bone mineral density in ChineseJournal of cellular and molecular medicineFebruary 1, 2018Wu LF, Zhu DC, Wang BH, Lu YH, He P, Zhang YH, Gao HQ, Zhu XW, Xia W, Zhu H, et al.

(17) Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal MuscleFrontiers in physiologyJanuary 1, 2018Formicola L, Pannérec A, Correra RM, Gayraud-Morel B, Ollitrault D, Besson V, Tajbakhsh S, Lachey J, Seehra JS, Marazzi G, et al.

(18) The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophyScientific reportsSeptember 19, 2017Samant SA, Kanwal A, Pillai VB, Bao R, Gupta MP.

(19) A multiplexed immunocapture liquid chromatography tandem mass spectrometry assay for the simultaneous measurement of myostatin and GDF-11 in rat serum using an automated sample preparation platformAnalytica chimica actaAugust 1, 2017Zhao Y, Liu G, Zambito FC, Zhang YJ, DeSilva BS, Kozhich AT, Shen JX.

(20) Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and diseaseProceedings of the National Academy of Sciences of the United States of AmericaJune 27, 2017Chen JL, Walton KL, Hagg A, Colgan TD, Johnson K, Qian H, Gregorevic P, Harrison CA.

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GDF-8/Myostatin Protein

GDF-8/Myostatin Protein

GDF-8/Myostatin Protein

GDF-8/Myostatin Protein

GDF-8/Myostatin Protein

Recombinant Human/Mouse/Rat GDF-8/Myostatin Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human/Mouse/Rat GDF-8/Myostatin Protein, CF from R&D Systems, a Bio-Techne Brand

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