SIRP alpha/CD172a Fc Chimera Protein 4546-SA-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSIRP alpha/CD172a Fc Chimera Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $491.00Supplier Page View Company Product Page
Catalog Number4546-SA-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size50 ug
Molecule NameSIRP alpha/CD172a
NCBI Full Gene Namesignal regulatory protein alpha
NCBI Gene AliasesCD172A, PTPNS1, SIRP, P84, MYD-1, MFR, BIT, SHPS1
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 70-105 kDa, reducing conditions
Theoretical: 64 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemCHO-derived Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 50 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signalsElifeDecember 1, 2022Yang Li, Yan Wu, Elena A Federzoni, Xiaodan Wang, Andre Dharmawan, Xiaoyi Hu, Hui Wang, Robert J Hawley, Sean Stevens, Megan Sykes, et al.SIRPα mAb (clone BL1H7) was from Abcam; recombinant human SIRPα/CD172a Fc chimera protein, CF (cat no. 4546-SA-050) was from R&D system; APC-conjugated anti-human IgG Fc (clone HP6017), PE-conjugated anti-human CD90

(2) CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signalseLifeDecember 1, 2022Yang Li, Yan Wu, Elena A Federzoni, Xiaodan Wang, Andre Dharmawan, Xiaoyi Hu, Hui Wang, Robert J Hawley, Sean Stevens, Megan Sykes, et al.SIRPα mAb (clone BL1H7) was from Abcam; recombinant human SIRPα/CD172a Fc chimera protein, CF (cat no. 4546-SA-050) was from R&D system; APC-conjugated anti-human IgG Fc (clone HP6017), PE-conjugated anti-human CD90

(3) A Novel Affinity Engineered Anti-CD47 Antibody With Improved Therapeutic Index That Preserves Erythrocytes and Normal Immune CellsFrontiers in oncologyJanuary 1, 2022Thaker YR, Rivera I, Pedros C, Singh AR, Rivero-Nava L, Zhou H, Swanson BA, Kerwin L, Zhang Y, Gray JD, et al.from 200 to 0.09 µg/mL. Without washing, 50 µL of purified SIRPα-Fc fusion protein (R&D Systems; Cat. 4546-SA-050) diluted at 0.4 µg/mL in FACS buffer at 37°C was added to each well and the incubation was prolonged

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SIRP alpha/CD172a Fc Chimera Protein

SIRP alpha/CD172a Fc Chimera Protein

SIRP alpha/CD172a Fc Chimera Protein

SIRP alpha/CD172a Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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SIRP alpha/CD172a Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

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