Active ERK2 Protein 1230-KS-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemActive ERK2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $561.00Supplier Page View Company Product Page
Catalog Number1230-KS-010
FormatSupplied in 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol
SpeciesHuman
Source/Expression SystemE. coli-derived Recombinant Human Active ERK2 Protein, CF
Size10 ug
Molecule NameERK2
NCBI Full Gene Namemitogen-activated protein kinase 1
NCBI Gene AliasesERK2, p41mapk, ERK-2, PRKM1, p42-MAPK, MAPK2, p38, PRKM2, P42MAPK, NS13, p40, ERT1, p41, ERK
Purity>80%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageThis product is stable at <= -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

Specifications/Features

Available conjugates: Sizes Available: 10 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrestLife science allianceAugust 1, 2023Acharya BR, Fang JS, Jeffery ED, Chavkin NW, Genet G, Vasavada H, Nelson EA, Sheynkman GM, Humphries MJ, Hirschi KK.in vitro kinase assay, 0.5 mM peptide substrates were incubated with 0.05 μg/μl recombinant ERK2 (Cat# 1230-kS-010; R&D systems) and 0.5 mM ATP (Cat# 9804; Cell signaling Technology) in 1X Kinase Buffer (Cat# 9802;

(2) Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanismNature communicationsJanuary 15, 2018Chen M, Wan L, Zhang J, Zhang J, Mendez L, Clohessy JG, Berry K, Victor J, Yin Q, Zhu Y, et al.

(3) IL-1β-induced and p38^MAPK-dependent activation of the mitogen-activated protein kinase-activated protein kinase 2 (MK2) in hepatocytes: Signal transduction with robust and concentration-independent signal amplificationThe Journal of biological chemistryApril 14, 2017Kulawik A, Engesser R, Ehlting C, Raue A, Albrecht U, Hahn B, Lehmann WD, Gaestel M, Klingmüller U, Häussinger D, et al.

(4) Effective combinatorial immunotherapy for castration-resistant prostate cancerNatureMarch 30, 2017Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, et al.isolated from mouse prostate tumors were co-transfected with recombinant active ERK2 (R&D Systems, 1230-KS-010) and p70S6K (R&D Systems, 896-KS-010) following manufacturer’s protocol of Chariot Protein Delivery

(5) PPARγ recruitment to active ERK during memory consolidation is required for Alzheimer's disease-related cognitive enhancementThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 12, 2014Jahrling JB, Hernandez CM, Denner L, Dineley KT.

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Recombinant Human Active ERK2 Protein, CF

Active ERK2 Protein

Active ERK2 Protein

Active ERK2 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Active ERK2 Protein from R&D Systems, a Bio-Techne Brand

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