Recombinant Human IFN-γ (carrier-free) 570202 from BioLegend

Product Specs
ItemRecombinant Human IFN-γ (carrier-free)
CompanyBioLegend
Price $83.00Supplier Page View Company Product Page
Catalog Number570202
Format0.22 µm filtered protein solution is in 10mM Sodium succinate, 4% Mannitol, pH 5.0
Size10 µg
ApplicationsBioassay
Gene Nameinterferon, gamma
NCBI Gene AliasesIFG, IFI, IMD69
NCBI Full Gene Nameinterferon gamma
Molecule NameIFN-gamma
Concentration10 and 25 µg sizes are bottled at 100 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool
SpeciesHuman

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) IL-12-engineered human PSMA-CAR T cells for the treatment of advanced prostate cancerMolecular Therapy AdvancesJune 11, 2026Lupita S. Lopez, Ziyou Cui, Yukiko Yamaguchi, John P. Murad, Zhiyuan Yang, Ke Zou, Jason Yang, Wen-Chung Chang, Stephen J. Forman, Vivien W. Chan, et al.(BioLegend, 572903). The media was changed once after 3–5 days to media containing GM-CSF, IFN-γ (BioLegend, 570202), LPS (Sigma-Aldrich, L3012-5MG), and IL-6 (BioLegend, 570804). To differentiate M2-like macrophages,

(2) Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetesiScienceMarch 20, 2026Jinxiu Rui, Madhav Kothari, Romy Kursawe, Mahsa Nouri Barkestani, Romi Genosar, Pamela Clark, Michael L. Stitzel, Kevan C. HeroldExpress,Cat# HY-13433 Bobcat339,Selleckchem,Cat# S668 CMRL1066,Gibco,Cat# 11530037 IFN-y,Biolegend,Cat# 570202 IL-1β,Biolegend,Cat# 579402 IFN-α,PBL Assay Science,Cat# 11101 TNF-α,Biolegend,Cat# 717904 DMSO,Sigma-Aldrich,Cat#

(3) Single-Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF SecretionAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2025Zhang Z, Dong J, Qiu M, Bai J, Cheng X, Song X.

(4) The IFNγ ‐ CIITA ‐ MHC II axis modulates melanoma cell susceptibility to NK ‐cell‐mediated cytotoxicityMolecular OncologyNovember 1, 2025Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeskinot indicated differently) Recombinant Human IFNγ (carrier‐free, BioLegend: Amsterdam, Netherlands, #570202) was added. Analyses were performed 24 h after treatment initiation. Either alone or in combination

(5) Human guanylate-binding protein (GBP) 1 inhibits replication of severe acute respiratory syndrome coronavirus 2Journal of VirologyOctober 23, 2025Rubaiyea Farrukee, Francesca Mordant, Charley Mackenzie-Kludas, Dejan Mesner, Masahiro Yamomoto, Clare Jolly, Andrew G. Brooks, Kanta Subbarao, Sarah L. Londrigan, Patrick C. Readingand Calu3 cells were incubated with different concentrations of recombinant mouse IFN-γ (Biolegend, #570202) or media alone (mock) for 24 h at 37°C. After incubation, RNA was extracted using the RNeasy Plus Mini

(6) Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 deliveryNature Biomedical EngineeringOctober 1, 2025John P. Murad, Lea Christian, Reginaldo Rosa, Yuwei Ren, Alyssa J. Buckley, Eric Hee Jun Lee, Lupita S. Lopez, Anthony K. Park, Jason Yang, Yukiko Yamaguchi, et al.first induced on PC3 prostate tumour cells overnight in 20 ng ml−1 recombinant human IFNγ (BioLegend, 570202). PD-L1-induced PC3 tumour cells were then co-cultured for 1 h at room temperature with supernatants

(7) A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain?Brain, Behavior, and ImmunityOctober 1, 2025Sara Villa-Hernandez, Julia Vlachaki Walker, Zoe Hore, Laura Fedele, Irene Zebochin, Yuening Li, Harvey Davis, Takashi Kanda, Fumitaka Shimizu, Leonie S. Taams, et al.10 ng/ml IL-17, Proteintech #Hz-1113, 10 ng/ml IL-4, BioLegend #574004, 100 ng/ml IFNγ, BioLegend #570202). The cells were then incubated with the cytokines for 4 h, after which the conditioned media were collected

(8) T-cell receptor/CD28-targeted immunotherapeutics selectively drive naive T-cell expansion to generate functional HIV-specific responsesJournal of VirologySeptember 23, 2025April L. Mueller, Sara Lamcaj, Scott Garforth, Christopher Hiner, Darien Woodley, Kitt Paraiso, Tian Mi, Simon Low, Ben Youngblood, Steven C. Almo, et al.the peptide of interest was added (2.5 µM), along with maturation factors IFN-γ (100 U) (BioLegend, 570202) and LPS (10 ng/µL) (Sigma, L6529). Following overnight incubation with maturation factors, mDCs were

(9) Spatiotemporal H(2)O(2) flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healingNature communicationsJuly 25, 2025O''Mara M, Zhang S, Knaus UG.BODIPY 558/568 phalloidin (B3475), DAPI (D-1306) and Fluo4-AM (F14201) by Invitrogen; recombinant human IFNγ (Biolegend, 570202); FITC-dextran 4 kDa (TdB Labs, 60842-46-8); GKT137831 (DC Chemicals, DC8118); Yoda1 (HY-18723), GsMTx4

(10) CD105+ fibroblasts support an immunosuppressive niche in women at high risk of breast cancer initiationBreast Cancer ResMay 15, 2025Eric G. Carlson, Jennifer C. Lopez, Yukiko Yamaguchi, Jackson Gibson, Saul J. Priceman, Mark A. LaBarge(BioLegend, 572903). The media was changed once after 4 days to media containing GM-CSF, IFN-γ (BioLegend, 570202), LPS (Sigma-Aldrich, L3012) and IL-6 (BioLegend, 570804). To differentiate anti-inflammatory macrophages,

(11) Peptide-Drug Conjugate for Therapeutic Reprogramming of Tumor-Associated Macrophages in Breast CancerAdvanced science (Weinheim, Baden-Wurttemberg, Germany)March 1, 2025Lepland A, Peranzoni E, Haljasorg U, Asciutto EK, Crespí-Amer M, Modesti L, Kilk K, Lombardia M, Acosta G, Royo M, et al.lipopolysaccharide (LPS, 100 ng mL−1, Sigma–Aldrich, catalog no. L4391) and IFNγ (20 ng mL−1, BioLegend, catalog no. 570202) were added and incubated overnight. All incubations were done at +37 °C. On day 7, 30 µm of MACTIDE‐V,

(12) Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetesNature metabolismNovember 1, 2024Hill TG, Gao R, Benrick A, Kothegala L, Rorsman N, Santos C, Acreman S, Briant LJ, Dou H, Gandasi NR, et al.ml−1 TNF and 1 ng ml−1 IFNγ (PEPROTECH, 211-11B, 315-01 A and 315-05; BioLegend, 579402, 570102 and 570202). To ensure complete blockage of the gap junction connexin-36, MFQ (Merck Life Science, PHR1705) or

(13) BTN3A1 expressed in cervical cancer cells promotes Vγ9Vδ2 T cells exhaustion through upregulating transcription factors NR4A2/3 downstream of TCR signalingCell communication and signaling : CCSSeptember 28, 2024Liu J, Wu M, Yang Y, Mei X, Wang L, Wang J, Wang Z, He S, Liu H, Jiang H, et al.cells stimulated by IFN-γ, CC cell lines (CaSki and HeLa-luci) were treated with IFN-γ (100 ng/ml, 570202, Biolegend), co-cultured with or without the addition of anti-human IFN-γ neutralizing antibody (10

(14) Cell therapy using ex vivo reprogrammed macrophages enhances antitumor immune responses in melanomaJournal of Experimental & Clinical Cancer ResearchSeptember 14, 2024Satish kumar Reddy Noonepalle, Maria Gracia-Hernandez, Nima Aghdam, Michael Berrigan, Hawa Coulibaly, Xintang Li, Christian Zevallos-Delgado, Andrew Pletcher, Bryan Weselman, Erica Palmer, et al.manufacturer’s instruction, which included LPS (10ng/mL) and recombinant human IFNγ (Biolegend, Cat # 570202) (50ng/mL) for two days. M1-like macrophages were either pretreated with HDAC6 inhibitor (NextA) (5µM)

(15) Mcl-1 mediates intrinsic resistance to RAF inhibitors in mutant BRAF papillary thyroid carcinomaCell death discoveryApril 15, 2024Cavallo MR, Yo JC, Gallant KC, Cunanan CJ, Amirfallah A, Daniali M, Sanders AB, Aplin AE, Pribitkin EA, Hartsough EJ.(5 × 105) in a 10 cm plate and cultured with 100 ng/mL OPN (#557102) and 20 ng/mL IFNγ (Biolegend #570202) or with 10 nM Navitoclax for 6–21 days prior to use in experiments. Media changes with fresh recombinant

(16) Precise analysis of single small extracellular vesicles using flow cytometrySci RepMarch 29, 2024Hisano Kobayashi, Takayuki Shiba, Takeshi Yoshida, Dilireba Bolidong, Koroku Kato, Yoshiki Sato, Mao Mochizuki, Takafumi Seto, Shuichi Kawashiri, Rikinari Hanayamain Advanced DMEM with 2% sEV-depleted FBS containing 0 or 100 ng/mL recombinant human IFN-γ (Cat. # 570202; BioLegend, San Diego, CA, USA) at 37 °C for 24 h. The 10 K sup was recovered from the culture medium

(17) Novel role of bone morphogenetic protein 9 in innate host responses to HCMV infectionEMBO ReportsMarch 11, 2024Markus Stempel, Oliver Maier, Baxolele Mhlekude, Hal Drakesmith, Melanie M Brinkmannhuman IFNβ was purchased from PeproTech (#300-02BC), recombinant IFNα2 (#592702) and recombinant IFNγ (#570202) were obtained from BioLegend. PNGase F (#P0704S) was obtained from New England Biolabs, and DMH1 (#S7146)

(18) Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinomaNature communicationsFebruary 2, 2024Liu C, Zhou C, Xia W, Zhou Y, Qiu Y, Weng J, Zhou Q, Chen W, Wang YN, Lee HH, et al.Santa Cruz Biotechnology. Human IL-4 (cat. no. 200-04) was obtained from PeproTech. Human IFN-γ (cat. no. 570202) was obtained from BioLegend. Mouse IL-4 (cat. no. 51084-MNAE) and mouse IFN-γ (cat. no. 50709-MNAH)

(19) Single-cell analysis reveals a weak macrophage subpopulation response to Mycobacterium tuberculosis infectionCell ReportsNovember 28, 2023Sydney L. Solomon, Bryan D. Brysonrecombinant proteins" Recombinant Human M-CSF,Biolegend,572902 Recombinant Human IFN- γ,Biolegend,570202 RPMI 1640,ThermoFisher Scientific,11835055 HEPES,ThermoFisher Scientific,15360–080 L-Glutamine,Sigma Aldrich

(20) MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma CellsCancersJune 29, 2023Song KY, Han YH, Roehrich H, Brown ME, Torres-Cabala C, Giubellino A.cultured with tumor-specialized media containing 2% FBS. Cells were treated with 25 ng/mL of IFN-γ (570202, BioLegend, San Diego, CA, USA) and MET inhibitors for 48 h with fresh replacements after 24 h. Cells

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4/3/2023Efficient Recombinant Human IFN-Gamma from BioLegend Soheil TavakolpourThis is a recombinant Human IFN-Y, which I used for activation of human monocyte cell line. THP-1 monocytes are differentiated into macrophages by 24 h incubation with 150 nM phorbol 12-myristate 13-... Read Review

Recombinant Human IFN-γ (carrier-free) from BioLegend

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Recombinant Human IFN-γ (carrier-free) from BioLegend

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