Recombinant Human TSG-6 Protein, CF 2104-TS-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TSG-6 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $568.00Supplier Page View Company Product Page
Catalog Number2104-TS-050
Size50 ug
ApplicationsBinding Activity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 40 kDa, reducing conditions
Theoretical: 30.5 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameTSG-6
Source/Expression SystemNS0-derived Recombinant Human TSG-6 Protein, CF
NCBI Full Gene NameTNF alpha induced protein 6
NCBI Gene AliasesTSG-6, TSG6
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Effects of Release of TSG-6 from Heparin Hydrogels on Supraspinatus Muscle RegenerationTissue Engineering Part AFebruary 1, 2025Joseph J. Pearson, Jiahui Mao, Johnna S. Temenoffanimal model.4,7,24–26 In vivo growth factor release For in vivo growth factor release, TSG-6 (R&D Systems, 2104-TS-050) was fluorescently tagged with Alexa Fluor 647 NHS ester (Invitrogen, Microscale Kit, A30009) by combining

(2) TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cellsPloS oneJanuary 1, 2025Eom YW, Hong JE, Jung PY, Yoon Y, Yoo SH, Hong J, Rhee KJ, Regmi B, Fatima S, Kim MY, et al.

(3) Chemical modification of hyaluronan oligosaccharides differentially modulates hyaluronan-hyaladherin interactionsThe Journal of biological chemistrySeptember 1, 2024Dodd RJ, Blundell CD, Sattelle BM, Enghild JJ, Milner CM, Day AJ.

(4) Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosisNeural regeneration researchMay 1, 2024Ding M, Jin L, Wei B, Cheng W, Liu W, Li X, Duan C.

(5) Glucocorticoid activates STAT3 and NF-κB synergistically with inflammatory cytokines to enhance the anti-inflammatory factor TSG6 expression in mesenchymal stem/stromal cellsCell death & diseaseJanuary 18, 2024Huang P, Sun R, Xu C, Jiang Z, Zuo M, Li Y, Liu R, Gong P, Han Y, Fang J, et al.temperature, and again washed with PBS. Added samples and a standard of human recombinant TSG6 protein (2104-TS-050, R&D Systems, MN, USA) and incubated for 2 h at room temperature. Then, washed the plate, added biotinylated

(6) Role of TGF-β and p38 MAPK in TSG-6 Expression in Adipose Tissue-Derived Stem Cells In Vitro and In VivoInternational journal of molecular sciencesDecember 29, 2023Kwon HY, Yoon Y, Hong JE, Rhee KJ, Sohn JH, Jung PY, Kim MY, Baik SK, Ryu H, Eom YW.

(7) Effect of Expansion Media on Functional Characteristics of Bone Marrow-Derived Mesenchymal Stromal CellsCellsAugust 19, 2023Jakl V, Popp T, Haupt J, Port M, Roesler R, Wiese S, Friemert B, Rojewski MT, Schrezenmeier H.

(8) Monocyte adhesive hyaluronan matrix induced by hyperglycemia in diabetic lung injuriesThe Journal of biological chemistryAugust 1, 2023Wang AJ, Ren J, Wang A, Hascall VC.

(9) Highly sensitive quantification of bacterial chondroitin in a culture based on ELISA techniquesJournal of microbiological methodsNovember 1, 2022Suzuki K, Kaseyama-Takemoto H, Ito S.

(10) The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye DiseaseThe ocular surfaceApril 1, 2022Oh JY, Ryu JS, Kim HJ, Kouvatsos N, Dodd RJ, Choi SH, Kim YJ, Milner CM, Day AJ.

(11) Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside EpidermisJID InnovDecember 1, 2021Evrard C, Faway E, De Vuyst E, Svensek O, De Glas V, Bergerat D, Salmon M, De Backer O, Flamion B, Le-Buanec H, et al.

(12) Therapeutic Effects of Human Mesenchymal Stem Cells in a Mouse Model of Cerebellar Ataxia with NeuroinflammationJournal of clinical medicineNovember 13, 2020Nam Y, Yoon D, Hong J, Kim MS, Lee TY, Kim KS, Lee HW, Suk K, Kim SR.

(13) Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microgliaJournal of neuroinflammationMay 11, 2020Yang H, Wu L, Deng H, Chen Y, Zhou H, Liu M, Wang S, Zheng L, Zhu L, Lv X.

(14) Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the CellsCellsSeptember 5, 2019Bartosh TJ, Ylostalo JH.

(15) STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammationProceedings of the National Academy of Sciences of the United States of AmericaAugust 13, 2019Nepal S, Tiruppathi C, Tsukasaki Y, Farahany J, Mittal M, Rehman J, Prockop DJ, Malik AB.containing 5% CO2 (15). Adoptive Transfer of BMMФs in Mice. BMMФs were stimulated with 400 ng/mL rTSG6 (2104-TS-050; R&D Systems) or 100 ng/mL rIL-4 (214-14; Peprotech) for 6 h in culture conditions in vitro, and adoptively

(16) IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenanceJournal of dermatological scienceMay 1, 2019Muraguchi T, Nanba D, Nishimura EK, Tashiro T.

(17) Intravascular heavy chain-modification of hyaluronan during endotoxic shockBiochemistry and biophysics reportsMarch 1, 2019Ni K, Gill A, Cao D, Koike K, Schweitzer KS, Garantziotis S, Petrache I.

(18) Bone Marrow Derived Mesenchymal Stromal Cells Ameliorate Ischemia/Reperfusion Injury-Induced Acute Kidney Injury in Rats via Secreting Tumor Necrosis Factor-Inducible Gene 6 ProteinBioMed research internationalJanuary 1, 2019Chen Y, Tang X, Li P, Zhou Y, Xue T, Liu J, Yu C.culture; in group C: serum-free medium with 150μM CoCl2 and 0.1μg/ml recombinant human TSG-6 (rTSG-6, 2104-TS-050, R&D Systems) were added for a 48 h incubation after normoxic culture. Before the stimulation experiments,

(19) The role of TSG-6 and uroplakin III in bladder pain syndrome/ interstitial cystitis in rats and humansIranian journal of basic medical sciencesNovember 1, 2017Lv YS, Gao R, Lin QM, Jiang T, Chen Q, Tang SX, Mao HP, Zhou HL, Cao LS.

(20) TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic CellsMediators of inflammationJanuary 1, 2017Kui L, Chan GC, Lee PP.CA, USA) and media, pretreated with recombinant human TSG-6 (rhTSG-6) (1000 ng/mL; R&D Systems cat #2104-TS-050) overnight, at 37∘ C in 5% CO2 . The duration of CpG-A or R837 stimulation was 3 hours for RT-qPCR, 6

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Recombinant Human TSG-6 Protein, CF

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Recombinant Human TSG-6 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human TSG-6 Protein, CF from R&D Systems, a Bio-Techne Brand

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