Description
Cylindrospermopsin is a tricyclic alkaloid hepatotoxin produced by cyanobacteria. Cylindrospermopsin exhibits a completely different mechanism of toxicity than microcystins by targeting/inhibiting the synthesis of glutathione, proteins, and pyrimidine nucleotides. Cylindrospermopsin is considered to be genotoxic. It was shown to break double stranded DNA and reduce cell viability in HepG2 cells