DAMGO 1171/1 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemDAMGO
CompanyTocris Bioscience, a Bio-Techne Brand
Price $111.00Supplier Page View Company Product Page
Catalog Number1171/1
Size1 mg
Molecular Weight513.7
TypePeptides
Purity95%
Molecule Name[D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin
FormulaC26H35N5O6
StorageStore at -20°C

Specifications/Features

Sizes Available: 1 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Practical quantification of immunohistochemistry antigen concentrations and reaction-diffusion parametersbioRxivApril 24, 2026Woody Perng, Berenice Mbiribindi, Benjamin Thomas Andrews, Xiangdan Wang, Debra Dunlap, Jeff Eastham, Hai Ngu, Andrei Chernyshev, Darya Orlova, Franklin V. Pealesources were: anti-BCL2- AlexaFluor™-647 (cat. # NBP2-34513AF647) and mouse IgG isotype control clone 11711 AlexaFluor™-647 (cat. #: IC002R; Novus Biologicals, LLC); normal goat serum (cat. # 005-000-121; Jackson ImmunoResearch Laboratories

(2) Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain TherapyFASEB JFebruary 15, 2026Sara A. Dochnal, Yixing Du, Daniella Bandari, Kaue Franco Malange, Jack Bryant, Julia Borges Paes Lemes, Abby Whitford, Anna R. Cliffe, Prashant Mali, Kim Dore, et al.Biotechnology,0.5 μM KCl,Sigma P5405,"10 mM, 50 mM" Forskolin,Selleckchem S2449,25 μM DAMGO,Tocris 1171,1 μM Naloxone hydrochloride dihydrate,Sigma N7758,10 μM Bradykinin,MedChemExpress HY‐P0206,1 μM Prostaglandin E2

(3) Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain TherapyFASEB JFebruary 3, 2026Sara A. Dochnal, Yixing Du, Daniella Bandari, Kaue Franco Malange, Jack Bryant, Julia Borges Paes Lemes, Abby Whitford, Anna R. Cliffe, Prashant Mali, Kim Dore, et al.Biotechnology,0.5 μM KCl,Sigma P5405,"10 mM, 50 mM" Forskolin,Selleckchem S2449,25 μM DAMGO,Tocris 1171,1 μM Naloxone hydrochloride dihydrate,Sigma N7758,10 μM Bradykinin,MedChemExpress HY‐P0206,1 μM Prostaglandin E2

(4) Vδ1 T-cell subset appears to be responsive to PD-1 blockade therapy and is associated with survival in melanomaJournal for ImmunoTherapy of CancerJanuary 20, 2026Nicola Herold, Jonas Bochem, Johanna Leyens, Svenja Wingerter, Stephan Forchhammer, Janine Spreuer, Malte Deseke, Can Yurttas, Paola Nocerino, Rita Antunes dos Reis, et al.Santa Cruz Biotechnology) or the corresponding isotype controls rabbit IgG (SP137; abcam), mouse IgG1 (11711; R&D Systems). Whole slide scans were acquired using a NanoZoomer V.2.0-HT digital slide scanner (Hamamatsu).

(5) GTP release-selective agonists prolong opioid analgesic efficacyNatureDecember 17, 2025Edward L. Stahl, Matthew A. Swanson, Vuong Q. Dang, Michael D. Cameron, Nicole M. Kennedy, Thomas D. Bannister, Laura M. BohnGDP (G7127). Cayman Chemical: PZM21 (20576-10), fentanyl citrate (22659) and GTPγS (35098). DAMGO (11711) was from Tocris Bioscience. Oliceridine (TRV-130; 510256) was from MedKoo Biosciences. Dynorphin A

(6) Characterization of the GTPγS release function of a G protein-coupled receptorNat CommunDecember 17, 2025Laura M. Bohn, Edward L. StahlMI, USA): fentanyl citrate (22659) and GTPγS (35098). Tocris Bioscience (Bristol, UK): DAMGO (Cat. 11711) and β-FNA (0926). Cell Signaling Technology (Danvers, MA): rabbit anti-HA (3724S, Lot 8), mouse anti-

(7) CXCL5 neutralization mitigates cancer cachexia by disrupting CAF-cancer cell crosstalkJ Biomed SciDecember 15, 2025Hyun-Jun Kim, Seon-Wook Kim, Jun-Hyeong Kim, Sang-Hoon Lee, Kyoung-Hwan Joo, Soo Young Lee, Hyunju Lee, Jung-Joon Min, Sang-Hee Cho, Da-Woon Jung, et al.(R&D Systems, MAB-254, clone 33160, MN, USA) and IgG1 monoclonal antibody (R&D Systems, MAB-002, clone 11711, MN, USA) were treated for 3 d prior to transplantation via intraperitoneal (IP) injection. Evidence

(8) Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addictioneLifeDecember 1, 2025Ramesh Chittajallu, Anna Vlachos, Adam P Caccavano, Xiaoqing Yuan, Steven Hunt, Daniel Abebe, Edra London, Kenneth A Pelkey, Chris J McBainCGP55845A (Cat. No. 1248/10), Picrotoxin (Cat. No. 1128), bicuculline (Cat. No. 0109/10), DAMGO (Cat. No. 1171/1), CTAP (Cat. No. 1560/1), and DHβE (Cat. No. 2349) were all purchased from Biotechne/Tocris (MN, USA);

(9) Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addictionElifeDecember 1, 2025Ramesh Chittajallu, Anna Vlachos, Adam P Caccavano, Xiaoqing Yuan, Steven Hunt, Daniel Abebe, Edra London, Kenneth A Pelkey, Chris J McBainCGP55845A (Cat. No. 1248/10), Picrotoxin (Cat. No. 1128), bicuculline (Cat. No. 0109/10), DAMGO (Cat. No. 1171/1), CTAP (Cat. No. 1560/1), and DHβE (Cat. No. 2349) were all purchased from Biotechne/Tocris (MN, USA);

(10) 5-HT(7) antagonists confer analgesia via suppression of neurotrophin overproduction in submucosal nerves of mouse models with visceral hypersensitivityThe Journal of physiologySeptember 1, 2025Lee TY, Lin YH, Chang WY, Lin LY, Chang CF, Kuo WT, Tu CH, Wu MS, Hsin LW, Yu LC.monoclonal mouse IgG1 antibodies developed against human proteins. The mouse IgG1 isotype control (clone #11711) (#MAB002; R&D Systems) was used at 1 µg mL−1 to confirm antibody specificity (Hsu et al., 2016). In

(11) TCR activation stimulates regulated intramembrane proteolysis of L-selectin by presenilin 1 and localized proteasomal degradation of the cytoplasmic tailJournal of Biological ChemistryJuly 10, 2025Owen R. Moon, Andrew C. Newman, Abdullah S. Alanazi, Sophie C. Wehenkel, Katarzyna Gawel-Bęben, Aleksandar Ivetic, David A. A Price, Vera Knäuper, Ann Agermixtures were costained for CD19 using anti-CD19-APC (H1B18) (BD Biosciences) with isotype control 11711-APC (IgG1κ) (R&D Systems) and CD62L on CD19 negative MOLT-3 T cells analyzed. Cell surface L-selectin

(12) GPR56/ADGRG1 induces biased Rho-ROCK-MLC and JAK-STAT3 signaling to promote amoeboid-like morphology and IL-6 upregulation in melanoma cellsCell Commun SignalMay 29, 2025Kuan-Yeh Huang, Kwai-Fong Ng, Kuan-Yu I, Yu-Chi Chang, Hsin-Yi Chen, Ya-Fang Chiu, Chuan-Mao Hung, Wan-Chen Yu, Tse-Ching Chen, Martin Stacey, et al.antibodies (mAbs) were developed in-house as described previously [43]. Mouse isotype control IgG1 (Clone 11711) was from R&D System (MN, USA). Cell culture All culture media were supplemented with 10% heat inactivated

(13) Active synthesis of type I collagen homotrimer in Dupuytren's fibrosis is unaffected by anti-TNF-α treatmentJCI InsightMay 8, 2025Kate Williamson, Katie J. Lee, Emma L. Beamish, Alan Carter, Jade A. Gumbs, Gabriella Cooper, Niamh S. O'Heneghan-Yates, Lisa A. Menezes, Graham Cheung, Daniel Brown, et al.anti–human TNF-α antibody (MAB610, clone 28401, R&D Systems, ) or mouse IgG1 Isotype Control (MAB002, 11711, R&D Systems), along with 2.5 μCi/mL [14C]proline overnight as required. Labeling media were reserved

(14) Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid LeukemiaACS OmegaMay 6, 2025Georgios Pantouris, Leepakshi Khurana, Pathricia Tilstam, Alison Benner, Thomas Yoonsang Cho, Martin Lelaidier, Mathieu Perrée, Zoe Rosenbaum, Lin Leng, Francine Foss, et al.mouse F(ab)2 IgG (H + L) APC-conjugated antibody (catalog#F0101B), and mouse IgG1 isotype control (clone 11711, catalog#MAB002) were purchased from R&D systems. The neutralizing antihuman CD74 (clone LN-2, catalog#ab9514)

(15) Syncytial therapeutics: Receptor-specific and direct-to-cytosol biologic drug delivery mediated by measles fusion complexJournal of Controlled ReleaseApril 10, 2025Victor A. Garcia, Casim A. Sarkar, Brenda M. Ogleclone A12-7D4), anti-CD46 (Biolegend, clone TRA-2-10), or an IgG1-κ isotype control (R&D Systems, clone 11711) primary antibody for 45-60 min rocking at 4 °C. Cells were centrifuged, washed as previously, centrifuged

(16) Enhancement of Human Immunodeficiency Virus-Specific CD8+ T Cell Responses with TIGIT Blockade Involves TrogocytosisPathogensDecember 23, 2024Nazanin Ghasemi, Kayla A. Holder, Danielle P. Ings, Michael D. Grantindividual wells of a 96-well round bottom plate (Thermo Fisher Scientific) and IgG1 isotype control (clone 11711, R&D Systems, Minneapolis, MN, USA) or anti-TIGIT mAb (clone MBSA43, Thermo Fisher Scientific) added

(17) T lymphocyte-derived IFN-γ facilitates breast cancer cells to pass the blood-brain barrier: An in vitro study corroborating translational dataHeliyonAugust 30, 2024Rute M.S.M. Pedrosa, Johan M. Kros, Benjamin Schrijver, Cor Berrevoets, Rute B. Marques, Casper C.H.J. van Eijck, Reno Debets, PieterJ.M. Leenen, Willem A. Dik, DanaA.M. MustafaIFNGR1/CD119 monoclonal antibody (clone 92101; R&D Systems) or 10 μg/ml Mouse IgG1 isotype control (clone 11711; R&D Systems). Subsequently, the cancer cells were incubated overnight with CM from activated bulk T lymphocytes

(18) Distinct characteristics of unique immunoregulatory canine non-conventional TCRαβpos CD4negCD8αneg double-negative T cell subpopulationsFrontiers in ImmunologyAugust 9, 2024Laura Karwig, Peter F. Moore, Gottfried Alber, Maria EschkeR&D, Biotechne, Wiesbaden, Germany) was used at 10 µg/ml. A nonblocking mouse IgG1 antibody (clone 11711, R&D, Biotechne, Wiesbaden, Germany) was added as control to rule out unspecific effects of the neutralizing

(19) Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosisThe Journal of biological chemistryJune 1, 2024Calver JF, Parmar NR, Harris G, Lithgo RM, Stylianou P, Zetterberg FR, Gooptu B, Mackinnon AC, Carr SB, Borthwick LA, et al.anti-galectin-3 mAb (Abcam, Clone No. EPR19244), mouse IgG1 isotype control mAb (R&D Systems, Clone No. 11711), or rabbit IgG isotype control mAb (Abcam, Clone No. EPR25A). FTs and wash steps were collected until

(20) β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte HomeostasisInternational journal of molecular sciencesApril 26, 2024Hussain MT, Austin-Williams S, Wright TD, Dhawan UK, Pinto AL, Cooper D, Norling LV.β1-integrin (Clone: P5D2; R&D Systems, Minneapolis, MN, USA) or 15 µg/mL of mouse IgG1 isotype control (Clone:11711; R&D Systems, Minneapolis, MN, USA) were used. 4.5. NanoFCM Quantification and Analysis Prior to use,

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DAMGO

DAMGO from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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DAMGO from Tocris Bioscience, a Bio-Techne Brand

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