Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein 7150-RS-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse R-Spondin 1 (CHO-expressed) Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $300.00Supplier Page View Company Product Page
Catalog Number7150-RS-025
Size25 ug (also 50 ug, 250 ug)
Source/Expression SystemCHO-derived Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein
SpeciesMouse
Molecule NameR-Spondin 1
NCBI Full Gene NameR-spondin 1
NCBI Gene AliasesRspondin, R-spondin
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 40-43 kDa, reducing conditions
Theoretical: 27 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Loss of function of Adducin 3 (ADD3) causes abnormal development and impaired barrier function of human and mouse bile duct cells resulting in increased incidence and severity of Biliary AtresiaeBioMedicineDecember 1, 2025Jerry LH. Ha, Yongqin Ye, Hailong Liu, Zhongluan Wu, Amy WY. Wai, Niwei Yan, Yim Cheung, Man-Ting So, Yuelan Zheng, Clara SM. Tang, et al.A83.01 (Tocris; CAS Number 909910-43-6), 10 μM Forskolin (Tocris; Cat. #: 1099), 500 ng/ml R-Spondin 1 (7150-RS-025; R&D), 100 ng/ml Noggin (250-38- 20UG; Peprotech), 100 ng/ml Wnt3a (1324-WN-010; R&D) and 250 ng/ml

(2) Animal and organoid models to elucidate the anti-fibrotic effect of steroid on biliary atresiaPediatric Surgery InternationalAugust 5, 2024Fangran Liu, Vincent Chi Hang Lui, Zhongluan Wu, Paul David Blakeley, Clara Sze Man Tang, Paul Kwong Hang Tam, Kenneth Kak Yuen Wong, Patrick Ho Yu Chung10 mM Nicotinamide (Sigma), 5 µM A83.01 (Tocris), 10 µM Forskolin (Tocris), 500 ng/ml R-Spondin 1 (7150-RS-025; R&D), 100 ng/ml Noggin (250-38-20UG; Peprotech), 100 ng/ml Wnt3a (1324-WN-010; R&D) and 250 ng/ml Amphotericin B

(3) The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell sizebioRxiv : the preprint server for biologyApril 11, 2024Xie S, Zhang S, de Medeiros G, Liberali P, Skotheim JM.

(4) Dysregulation of Wnt/β-catenin signaling contributes to intestinal inflammation through regulation of group 3 innate lymphoid cellsNature communicationsApril 1, 2024Hao J, Liu C, Gu Z, Yang X, Lan X, Guo X.

(5) ESRRG-PKM2 axis reprograms metabolism to suppress esophageal squamous carcinoma progression and enhance anti-PD-1 therapy efficacyJournal of translational medicineSeptember 7, 2023Wang T, Zhu Y, Chen L, Zhang W, Qi H, Shi X, Zhong M, Chen H, Li Q.

(6) Human liver organoid derived intra-hepatic bile duct cells support SARS-CoV-2 infection and replicationScientific ReportsDecember 1, 2022Vincent Chi-Hang Lui, Kenrie Pui-Yan Hui, Rosanna Ottakandathil Babu, Haibing Yue, Patrick Ho-Yu Chung, Paul Kwong-Hang Tam, Michael Chi-Wai Chan, Kenneth Kak-Yuen WongNicotinamide (Sigma-Aldrich), 5 µM A83.01 (Tocris), 10 µM Forskolin (Tocris), 500 ng/ml R-Spondin 1 (7150-RS-025; R&D), 100 ng/ml Noggin (250-38-20UG; Peprotech), 100 ng/ml Wnt3a (1324-WN-010; R&D) and 250 ng/ml Amphotericin B

(7) Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesisNature communicationsNovember 2, 2022Hiroto A, Kim WK, Pineda A, He Y, Lee DH, Le V, Olson AW, Aldahl J, Nenninger CH, Buckley AJ, et al.

(8) Cold atmospheric plasma differentially affects cell renewal and differentiation of stem cells and APC-deficient-derived tumor cells in intestinal organoidsCell death discoveryFebruary 15, 2022Hadefi A, Leprovots M, Thulliez M, Bastin O, Lefort A, Libert F, Nonclercq A, Delchambre A, Reniers F, Devière J, et al.

(9) Mitochondrial transcription factor A in RORγt⁺ lymphocytes regulate small intestine homeostasis and metabolismNature communicationsJuly 22, 2021Fu Z, Dean JW, Xiong L, Dougherty MW, Oliff KN, Chen ZE, Jobin C, Garrett TJ, Zhou L.

(10) Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1Cellular and molecular gastroenterology and hepatologyJanuary 1, 2021Dunbar K, Valanciute A, Lima ACS, Vinuela PF, Jamieson T, Rajasekaran V, Blackmur J, Ochocka-Fox AM, Guazzelli A, Cammareri P, et al.

(11) Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolitesBMC microbiologyJuly 11, 2020Dougherty MW, Kudin O, Mühlbauer M, Neu J, Gharaibeh RZ, Jobin C.

(12) Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammationCell discoveryJanuary 1, 2019Cai Y, Zhu G, Liu S, Pan Z, Quintero M, Poole CJ, Lu C, Zhu H, Islam B, Riggelen JV, et al.

(13) Essential role of IFN-γ in T cell-associated intestinal inflammationJCI insightSeptember 20, 2018Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, Teshima T, Ayabe T, Selsted ME, Ouellette AJ.

(14) PDGFRα⁺ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivoProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2018Greicius G, Kabiri Z, Sigmundsson K, Liang C, Bunte R, Singh MK, Virshup DM.the next day the medium was changed to 0.1% FBS with recombinant RSPO1 or RSPO3 protein (catalog nos. 7150-RS-025 and 4120-RS-025, respectively; R&D Systems) as indicated (100 pg/mL to 500 ng/mL). Luciferase activity

(15) RSPOs facilitated HSC activation and promoted hepatic fibrogenesisOncotargetSeptember 27, 2016Yin X, Yi H, Wang L, Wu W, Wu X, Yu L.

(16) Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damageDevelopment (Cambridge, England)May 1, 2016Fernandez Vallone V, Leprovots M, Strollo S, Vasile G, Lefort A, Libert F, Vassart G, Garcia MI.

Be the First to Write a Review!

R-Spondin 1 Protein

R-Spondin 1 Protein

R-Spondin 1 Protein

Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map