Recombinant Human IL-6 (HEK293-expressed) Protein 7270-IL-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-6 (HEK293-expressed) Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $306.00Supplier Page View Company Product Page
Catalog Number7270-IL-025
Molecule NameIL-6
Source/Expression SystemHEK293-derived Recombinant Human IL-6 (HEK293-expressed) Protein
Size25 ug
SpeciesHuman
NCBI Full Gene Nameinterleukin 6
NCBI Gene AliasesCDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 22 kDa, reducing conditions
Theoretical: 20.8 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Loss of Function Mouse Models Reveal a Novel Regulatory Function for ULK1 in Myeloproliferative NeoplasmsMolecular and Cellular BiologySeptember 2, 2025Diana Saleiro, Jeremy Q. Wen, Markella Zannikou, Brian Lee, Ewa M. Kosciuczuk, Sarah D. Nehlsen, Adam Munshi, Xintong Chen, Chidera V. Oku, Briana Hryhorysak, et al.#403-ML-010, R&D Systems), mouse SCF (40ng/ml, #455-MC-020, R&D Systems) and human IL-6 (10ng/ml, #7270-IL-025, R&D Systems) and penicillin/streptomycin. The next day, the cells were transduced with mouse MigR1-Jak2V617F-GFP

(2) Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopmentDisease models & mechanismsNovember 1, 2023Sarieva K, Hildebrand F, Kagermeier T, Yentür Z, Becker K, Mayer S.Accutase (Merck, A6964). The cultures were treated with either IL-6 (35.25 ng/ml, 1.69 nM, R&D Systems, 7270-IL-025) or Hyper-IL-6 (100 ng/ml, 1.69 nM, R&D Systems, 8954-SR-025) diluted in 0.1% bovine serum albumin (BSA;

(3) Cytokine-Induced iNOS in A549 Alveolar Epithelial Cells: A Potential Role in COVID-19 Lung PathologyBiomedicinesOctober 3, 2023Barilli A, Recchia Luciani G, Visigalli R, Sala R, Soli M, Dall'Asta V, Rotoli BM.

(4) TGF-Beta Induces Activin A Production in Dermal Fibroblasts Derived from Patients with Fibrodysplasia Ossificans ProgressivaInternational journal of molecular sciencesJanuary 24, 2023de Ruiter RD, Wisse LE, Schoenmaker T, Yaqub M, Sánchez-Duffhues G, Eekhoff EMW, Micha D.BMP4 (AF-120-05ET, Peprotech, London, UK), Activin A (A4941, Sigma-Aldrich, St. Louis, USA), IL-6 (7270-IL-025, R&D systems, Minneapolis, USA), TNF-α (210-TA-020, R&D systems, Minneapolis, USA), or TGF-β (cat#4232-5,

(5) Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6RαScientific reportsJuly 19, 2022Cai Z, Tian S, Klein T, Tu L, Geenen LW, Koudstaal T, van den Bosch AE, de Rijke YB, Reiss IKM, Boersma E, et al.

(6) GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytesCell death & diseaseMay 20, 2022Manshouri T, Veletic I, Li P, Yin CC, Post SM, Verstovsek S, Estrov Z.

(7) Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migrationCell reportsMarch 8, 2022Ajay AK, Zhao L, Vig S, Fujiwara M, Thakurela S, Jadhav S, Cho A, Chiu IJ, Ding Y, Ramachandran K, et al.

(8) Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formationmAbsJanuary 1, 2022Chou CC, Hua KT, Chen MW, Wu CJ, Hsu CH, Wang JT, Hsiao M, Wei LH.

(9) A novel antibody for the detection of alternatively spliced secreted KLOTHO isoform in human plasmaPloS oneJanuary 1, 2021Jadhav S, Tripathi S, Chandrekar A, Waikar SS, Hsiao LL.

(10) The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironmentOncotargetDecember 8, 2020Wada Y, Tokuda K, Morine Y, Okikawa S, Yamashita S, Ikemoto T, Imura S, Saito Y, Yamada S, Shimada M.

(11) Down-regulation of IL-8 expression in human airway epithelial cells through helper-dependent adenoviral-mediated RNA interferenceCell ResearchMarch 3, 2005Hui Bi CAO, Anan WANG, Bernard MARTIN, David R KOEHLER, Pamela L ZEITLIN, A Keith TANAWELL, Jim HU

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IL-6 Protein

IL-6 Protein

IL-6 Protein

Recombinant Human IL-6 (HEK293-expressed) Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-6 (HEK293-expressed) Protein from R&D Systems, a Bio-Techne Brand

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