Recombinant Human TLR3 Protein, CF 1487-TR-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TLR3 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $420.00Supplier Page View Company Product Page
Catalog Number1487-TR-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameTLR3
Size50 ug
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 110-120 kDa, reducing conditions
Theoretical: 79.2 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human TLR3 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nametoll like receptor 3
NCBI Gene AliasesCD283, IIAE2, IMD83

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(1) Toll-like receptor 2 antagonists identified through virtual screening and experimental validationThe FEBS journalJuly 1, 2017Durai P, Shin HJ, Achek A, Kwon HK, Govindaraj RG, Panneerselvam S, Yesudhas D, Choi J, No KT, Choi S.

(2) Role of the Toll-like receptor 3 signaling pathway in the neuroprotective effect of sevoflurane pre-conditioning during cardiopulmonary bypass in ratsMolecular Medicine ReportsDecember 1, 2015JIN ZHOU, NAN ZHOU, XIAO-NING WU, HUI-JUAN CAO, YING-JIE SUN, TIE-ZHENG ZHANG, KE-YAN CHEN, DONG-MEI YUChina), Ponceau S (Beijing Solarbio Science & Technology Co., Ltd., Beijing, China), rat TLR3 (cat. no. 1487-TR-050), TRIF (cat. no. ab101232), IL-6 (cat. no. D6050), interferon (IFN)-β (cat. no. 41410-1), S100-β (cat.

(3) Cleaved/associated TLR3 represents the primary form of the signaling receptorJournal of immunology (Baltimore, Md. : 1950)January 15, 2013Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, Bonnin M, Ciancanelli MJ, Zhang SY, Funami K, et al.

(4) dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8Cell death and differentiationSeptember 1, 2012Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, Bonnin M, Lalaoui N, Mercier-Gouy P, Pachéco Y, et al.

(5) TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNAJournal of immunology (Baltimore, Md. : 1950)August 15, 2010Perrot I, Deauvieau F, Massacrier C, Hughes N, Garrone P, Durand I, Demaria O, Viaud N, Gauthier L, Blery M, et al.

(6) Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cellsAmerican journal of respiratory cell and molecular biologyJune 1, 2010Koarai A, Sugiura H, Yanagisawa S, Ichikawa T, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M.

(7) Activation of Toll-like receptor 3 augments myofibroblast differentiationAmerican journal of respiratory cell and molecular biologyJune 1, 2009Sugiura H, Ichikawa T, Koarai A, Yanagisawa S, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M.

Molecular Medicine Reports