5-Lipoxygenase (human, recombinant) 60402 from Cayman Chemical

Product Specs
Item5-Lipoxygenase (human, recombinant)
CompanyCayman Chemical
Price $528.00Supplier Page View Company Product Page
Catalog Number60402
NCBI Full Gene Namearachidonate 5-lipoxygenase
Source/Expression SystemInsect cells
NCBI Gene Aliases5-LO, 5-LOX, 5LPG, LOG5
Research AreaAlzheimer’s Disease, Arthritis (Non-Autoimmune), Cardiovascular System, Dyslipidemias, Endocrinology & Metabolism, Immunology & Inflammation, Inflammatory Lipid Mediators, Innate Immunity, Leukotrienes, Lipid Biochemistry, Lipids & Lipoproteins, Lipoproteins, Lipoxygenase Pathways, Metabolic Diseases, Neurodegenerative Disorders, Neuroscience, Pulmonary Diseases
Storage-80
OriginUSA
Size5 kU
Specieshuman
Format100 mM Tris-HCl, pH 8.0, with 5 mM EGTA, 1mM calcium chloride, and 30% glycerol
Molecular Weight78 kDa
PurityClarified lysate

Specifications/Features

EC Number: 1.13.11.34

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Carvacrol Arrests the Proliferation of Hypopharyngeal Carcinoma Cells by Suppressing Ornithine Decarboxylase and Hyaluronidase ActivitiesFrontiers in NutritionApril 8, 2022Kaneez Fatima, Suaib Luqman, Abha Meena10082147) were procured from Gibco, Thermo Fisher Scientific India Pvt. Ltd., Mumbai, India. LOX-5 (60402) was purchased from Cayman Chemical Company, USA. Sodium/potassium phosphate (RM 257, RM 249) and trichloroacetic

(2) Antiulcer Potential of Olea europea L. cv. Arbequina Leaf Extract Supported by Metabolic Profiling and Molecular DockingAntioxidants (Basel)April 22, 2021Arafa Musa et al.18 against the 5-LOX enzyme was investigated using human recombinant enzyme assay kits (catalog no. 60402 Cayman Chemical, Ann Arbor, MI, USA) following the manufacturer’s specifications. Stock solutions were

(3) Inhibition of Soybean 15-Lipoxygenase and Human 5-Lipoxygenase by Extracts of Leaves, Stem Bark, Phenols and Catechols Isolated From Lithraea caustica (Anacardiaceae)Frontiers in PharmacologyNovember 30, 2020Alejandra Muñoz-Ramírez, Carolina Mascayano-Collado, Andrés Barriga, Javier Echeverría, Alejandro Urzúa(Vásquez-Martínez et al., 2019), with minor modifications. In shortly, the enzyme (Cayman Chemical Item No. 60402) was diluted (1:500) in the assay buffer (HEPES 50 mM, EDTA 2 mM, ATP 10 μM and CaCl2 10 μM at pH 7.5)

(4) Metabolomic Analysis, Fast Isolation of Phenolic Compounds, and Evaluation of Biological Activities of the Bark From Weinmannia trichosperma Cav. (Cunoniaceae)Frontiers in PharmacologyMay 27, 2020Ruth Barrientos, Carlos Fernández-Galleguillos, Edgar Pastene, Mario Simirgiotis, Javier Romero-Parra, Shakeel Ahmed, Javier EcheverríaSigma-Aldrich® (Chile). The enzyme 5-lipoxygenase (human, recombinant) were from Cayman Chemical (Item No. 60402). Calcium chloride, sodium carbonate, sodium hydroxide, sodium nitrite, and potassium persulphate were

(5) N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's diseaseNature communicationsMay 12, 2020Lee JY, Han SH, Park MH, Song IS, Choi MK, Yu E, Park CM, Kim HJ, Kim SH, Schuchman EH, et al.(Cayman) at 37 °C for 2 h, respectively. The mixtures were incubated with 30 U of human 5-LOX (Cayman, 60402) containing 2 mM CaCl2 (Sigma-Aldrich), 1 mM ATP (Amresco) and 5 μM 13-HpODE (Cayman) as activators.

(6) The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed TissueFrontiers in immunologyJanuary 1, 2018Kern K, Schäfer SMG, Cohnen J, Pierre S, Osthues T, Tarighi N, Hohmann S, Ferreiros N, Brüne B, Weigert A, et al.

(7) Effect of lipopolysaccharide and cytokines on synthesis and secretion of leukotrienes from endometrial epithelial cells of pigsAnimal Reproduction ScienceMarch 14, 2016Barbara Jana, Joanna Czarzasta

(8) Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environmentInternational journal of cancerMarch 1, 2014Apostoli AJ, Skelhorne-Gross GE, Rubino RE, Peterson NT, Di Lena MA, Schneider MM, SenGupta SK, Nicol CJ.

(9) Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cellsPloS oneJanuary 1, 2011Xie Z, Bi C, Cheong LL, Liu SC, Huang G, Zhou J, Yu Q, Chen CS, Chng WJ.

(10) Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesisInternational Journal of Colorectal DiseaseSeptember 1, 2010Michał P. Wasilewicz, Blanka Kołodziej, Teresa Bojułko, Mariusz Kaczmarczyk, Violetta Sulżyc-Bielicka, Dariusz Bielicki, Katarzyna Ciepiela

(11) The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype – A link to gastric carcinogenesisCancer LettersMay 6, 2008Marino Venerito, Doerthe Kuester, Thomas Wex, Albert Roessner, Peter Malfertheiner, Gerhard Treiber

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5-Lipoxygenase (human, recombinant)

5-Lipoxygenase (human, recombinant)

5-Lipoxygenase (human, recombinant) from Cayman Chemical

Description

Specifications/Features

Cayman Chemical

Citations (11)

Reviews

5-Lipoxygenase (human, recombinant) from Cayman Chemical

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