Recombinant Human/Mouse/Rat Activin A Protein 338-AC-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human/Mouse/Rat Activin A Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $384.00Supplier Page View Company Product Page
Catalog Number338-AC-010
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
SpeciesHuman, Mouse, Rat
Molecule NameActivin A
Size10 ug (also 50 ug, 500 ug, 1 mg)
NCBI Full Gene Nameinhibin subunit beta A
NCBI Gene AliasesFRP, EDF
Purity>95%, by SDS-PAGE with silver staining
Molecular WeightObserved: 14 kDa, reducing conditions 24 kDa, non-reducing conditions
Theoretical: 13 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemCHO-derived Recombinant Human/Mouse/Rat Activin A Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) AMPK-p38 axis converts human pluripotent stem cells to naive stateiScienceMay 15, 2026Zhennan Yang, Yajing Liu, Huaigeng Xu, Junko Yamane, Akitsu Hotta, Wataru Fujibuchi, Jun K. YamashitaWako,Cat# 121-06663 Recombinant human LIF,Gibco,Cat# PHC9481 Recombinant human Activin A,R&D Systems,Cat# 338-AC-010 Recombinant human bFGF,FUJIFILM Wako,Cat# 068-04544 Recombinant human Noggin,R&D Systems,Cat# 6057-NG Recombinant

(2) Activin A-Endothelin-1 Axis Governs Pulmonary Vascular Remodeling: Mechanistic Basis for Emerging Therapies in PAHArterioscler Thromb Vasc BiolApril 2, 2026Novia Nurul Faizah, Gusty Rizky Teguh Ryanto, Sagita Mega Sekar Kencana, Yoko Suzuki, Tetsuya Hara, Hiromasa Otake, Noriaki EmotoPAECs were treated for 6 hours with recombinant human activin A (100 or 20 ng/mL in some cases; no. 338-AC-010; R&D Systems), recombinant human endothelin-1 (100 nmol/L; no. 4198-v; Peptide Institute), or vehicle.

(3) Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell DifferentiationAdvanced Healthcare MaterialsJanuary 1, 2026Ishita Jain, Brock Grenci, Hyeon Ryoo, Yang Yuan, Salman R. Khetani, Gregory H. Underhillsupplemented with 2% B27 (without Insulin) (Invitrogen, #0050129SA), 100 ng mL−1 Activin A (R&D systems, #338‐AC‐010), 10 ng mL−1 BMP4 (R&D, #314BP), and 20 ng mL−1 bFGF (Stemcell Technologies, #78 003) with daily media

(4) Modeling the Blood-Brain Barrier Using Human-Induced Pluripotent Stem CellsMethods in Molecular BiologyNovember 21, 2025Louise A. Mesentier-Louro, Natalie Suhy, Diede Broekaart, Michael Bula, Ana C. Pereira, Joel W. Blanchardplates. Accutase (ThermoFisher, Cat. no. A1110501). Activin A Protein (R & D Systems, Cat. no. 338-AC-010). Automated Cell Counter or Hemocytometer. BMP-4 (R & D Systems, Cat. no. 314-BP-050). Centrifuge.

(5) Establishment of human gastrulating stem cells with the capacity of stable differentiation into multiple gastrulating cell typesCell researchOctober 1, 2025Huang M, Chen M, Yuan G, Cui Y, Shen B, Liu Z, Zhang B, Chen J, Chen D, Qiu S, et al.

(6) Cyborg organoids integrated with stretchable nanoelectronics can be functionally mapped during developmentNature protocolsSeptember 1, 2025Lin Z, Wang W, Liu R, Li Q, Lee J, Hirschler C, Liu J.

(7) Expansion of human pluripotent stem cell-induced nephron progenitor cells (iNPCs) and the generation of nephron organoids from iNPCsNature protocolsAugust 29, 2025Huang B, Medina P, Ma T, Schreiber ME, Li Z.

(8) Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signalsCell reportsAugust 26, 2025D'Oliveira Albanus R, Zhang X, Zhao Z, Taylor HJ, Tang X, Han Y, Orchard P, Varshney A, Zhang T, Manickam N, et al.

(9) Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 DiabetesbioRxiv : the preprint server for biologyAugust 15, 2025Brown ME, Barra JM, Pina MR, Proia J, Brusko TM, Russ HA.

(10) The transcription factor IID subunit Taf13 is dispensable for TATA binding protein promoter recruitment and RNA polymerase II transcriptioniScienceJune 20, 2025Igor Martianov, Stephanie Le Gras, Guillaume Davidson, Irwin Davidsonand seeded into plates in the same medium where 2i and LIF were replaced by Activin A (R&D systems, 338-AC-010) and FGF2 (R&D systems, 233-FB-025). Cells were cultured for 3 days in the absence or presence of doxycycline. Blastocyst

(11) Ligand-specific regulation of a binary enhancer code dictating cellular senescenceProceedings of the National Academy of Sciences of the United States of AmericaJune 17, 2025Suter T, Friedman MJ, Tazearslan C, Merkurjev D, Ohgi K, Meluzzi D, Rosenfeld MG, Suh Y.senescent (>PD60) BJ fibroblasts were treated with SMAD2/3-regulating ligands Activin A (R&D Systems—338-AC-010), Inhibin A (R&D Systems—8506-AB-010), TGF-β2 (R&D Systems—302-B2-010), or combined TGF-β2+Inhibin A

(12) Mitophagy is induced in human engineered heart tissue after simulated ischemia and reperfusionJournal of cell scienceMay 1, 2025Nàger M, Larsen KB, Bhujabal Z, Kalstad TB, Rössinger J, Myrmel T, Weinberger F, Birgisdottir AB.

(13) Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signallingCell Stem CellMay 1, 2025Kristina S. Stapornwongkul, Elisa Hahn, Patryk Poliński, Laura Salamó Palau, Krisztina Arató, LiAng Yao, Kate Williamson, Nicola Gritti, Kerim Anlas, Mireia Osuna Lopez, et al.Nodal signalling activation with 25ng/ml Act-A (stock solution: 100μg/ml Act-A in 2mM HCl, R&D Systems, 338-AC-010), Wnt signalling activation with 3μM CHIR (stock solution: 10mM CHIR in DMSO, Sigma, #SML1046), Fgf

(14) Enhanced viability and functional maturity of iPSC-derived islet organoids by collagen-VI-enriched ECM scaffoldsCell stem cellApril 3, 2025Zhu D, Chen Z, Guo K, Xie Q, Zou Y, Mou Q, Zhou Z, Jin G.

(15) Reconstructing signaling histories of single cells via perturbation screens and transfer learningbioRxiv : the preprint server for biologyMarch 17, 2025Hutchins NT, Meziane M, Lu C, Mitalipova M, Fischer D, Li P.

(16) Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiationbioRxiv : the preprint server for biologyFebruary 11, 2025Hogrebe NJ, Schmidt MD, Augsornworawat P, Gale SE, Shunkarova M, Millman JR.

(17) Rescuing DNMT1 fails to fully reverse the molecular and functional repercussions of its loss in mouse embryonic stem cellsNucleic acids researchFebruary 8, 2025Elder E, Lemieux A, Legault LM, Caron M, Bertrand-Lehouillier V, Dupas T, Raynal NJ, Bourque G, Sinnett D, Gévry N, et al.

(18) NF2 is Essential for Human Endoderm DevelopmentAdvanced ScienceFebruary 8, 2025Minjin Jeong, Dongjun Han, Preetida Bhetariya, D. Bradley Welling, Miodrag Stojkovic, Konstantina M. Stankovic(Gibco, #11875093) supplemented with GlutaMAX (Gibco, # 35050061), 100 ng mL−1 Activin A (R&D SYSTEMS, 338‐AC‐010), 1x B27 (Gibco, #17504‐044), and 2.5 µM of CHIR99021 (TOCRIS, #4423). On day 2, the medium was again

(19) Zygotic activin a is dispensable for the mouse preimplantation embryo development and for the derivation and pluripotency of embryonic stem cells†Biology of ReproductionJanuary 14, 2025Eliza Winek, Lidia Wolińska-Nizioł, Katarzyna Szczepańska, Anna Szpakowska, Olga Gewartowska, Izabela Wysocka, Magdalena Grzesiak, Aneta Suwińskablastocysts were cultured in ESC medium with 500 ng/ml recombinant activin A protein (R&D Systems, 338-AC-010). To maintain a constant concentration of activin A throughout the culture, the old ESC + activin A

(20) GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesisbioRxiv : the preprint server for biologyJanuary 11, 2025Bisson JA, Gordillo M, Kumar R, de Silva N, Yang E, Banks KM, Shi ZD, Lee K, Yang D, Chung WK, et al.

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Activin A Protein

Activin A Protein

Activin A Protein

Activin A Protein

Activin A Protein

Recombinant Human/Mouse/Rat Activin A Protein from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Recombinant Human/Mouse/Rat Activin A Protein from R&D Systems, a Bio-Techne Brand

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