Recombinant Human/Mouse/Rat Activin A Protein, CF 338-AC-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human/Mouse/Rat Activin A Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $384.00Supplier Page View Company Product Page
Catalog Number338-AC-010/CF
SpeciesHuman, Mouse, Rat
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Molecule NameActivin A
Size10 ug (also 50 ug, 500 ug, 1 mg)
Source/Expression SystemCHO-derived Recombinant Human/Mouse/Rat Activin A Protein, CF
Purity>95%, by SDS-PAGE with silver staining
Molecular WeightObserved: 14 kDa, reducing conditions 24 kDa, non-reducing conditions
Theoretical: 13 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
NCBI Full Gene Nameinhibin subunit beta A
NCBI Gene AliasesFRP, EDF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) BMP9 Modulates IL-33 Signaling to Mitigate EndMT in Pulmonary Arterial HypertensionHypertensionFebruary 1, 2026Clarissa Becher, Esmee J. Groeneveld, Rozenn Quarck, Beau Neep, Xiaoke Pan, Robert Szulcek, Ly Tu, Christophe Guignabert, Harm Jan Bogaard, Paul B. Yu, et al.BMP4 (314-BP-010/CF), BMP6 (507-BP-020/CF), BMP9 (3209-BP-010/CF), BMP10 (2926-BP-025/CF), activin A (338-AC-010/CF), TGF-b1 (240-B-010/CF), and recombinant human soluble ST2/IL-33R Fc (523-ST-100) were obtained from

(2) Crucial roles of mesenchymal Gata2 in murine epididymal developmentProceedings of the National Academy of SciencesDecember 23, 2025Allyssa Fogarty, Shuai Jia, Jillian Wilbourne, Claire DuPuis, Fei Zhaovehicle; and tissues were cultured with 20ng/mL and 200ng/mL of recombinant Activin A (R&D Systems, 338-AC-010/CF), which were previously shown to be effective (23, 54). Tissues were cultured for 3 days with culture

(3) Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancerCell Stem CellJune 6, 2024Zahir Shah, Lei Tian, Zhixin Li, Lewei Jin, Jianying Zhang, Zhenlong Li, Tasha Barr, Hejun Tang, Mingye Feng, Michael A. Caligiuri, et al.,ThermoFisher Scientific,PHG0261 mTeSR1,StemCell technologies,85850 Recombinant Human/Mouse/Rat Activin A Protein,R&D Systems,338-AC-010/CF Recombinant Human BMP-4 Protein,R&D Systems,314-BP-010 Recombinant Human Thrombopoietin Protein,R&D Systems

(4) Optimizing Nodal, Wnt and BMP signaling pathways for robust and efficient differentiation of human induced pluripotent stem cells to intermediate mesoderm cellsFrontiers in Cell and Developmental BiologyJune 3, 2024Esmeralda Magro-Lopez, Elena Vazquez-Alejo, María de la Sierra Espinar-Buitrago, María Ángeles Muñoz-Fernández(cat.#72304, Stem Cell Technologies). Cells were then treated with 100 ng/mL human recombinant activin A (cat.#338-AC-010/CF, R&D Systems) or 3 μM CHIR99021 (cat.#4423, R&D Systems) for 24, 48 and 72 h, accordingly. Induction

(5) Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessmentiScienceFebruary 16, 2024Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba, et al.Corporation,Cat#012-04802 1-thioglycerol,Sigma-Aldrich,Cat#M1753-100ML Bone morphologic protein 4,R&D Systems,Cat#314-BP-010/CF Activin A,R&D Systems,Cat#338-AC-010/CF Vascular endothelial growth factor (VEGF),FUJIFILM Wako Pure Chemical Corporation,Cat#229-01313 IWR-1,Sigma-Aldrich,Cat#I0161-5MG IWP-2,Sigma-Aldrich,Cat#686770-61-6 Dulbecco’s

(6) Cell-free DNA as a potential biomarker of differentiation and toxicity in cardiac organoidseLifeJune 1, 2023Silver B, Gerrish K, Tokar E.99021 (4 µM; Selleck, S2924), BMP4 (0.36 pM; BioTechne, 314BP-010/CF), and ActA (0.08 pM; BioTechne, 338-AC-010/CF). On day 1, 166 µL of media was removed and replaced with 166 µL RPMI 1640 supplemented with B27 (no

(7) scTIE: data integration and inference of gene regulation using single-cell temporal multimodal databioRxiv : the preprint server for biologyMay 22, 2023Lin Y, Wu TY, Chen X, Wan S, Chao B, Xin J, Yang JYH, Wong WH, Wang YXR.

(8) Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory componentsNucleic acids researchApril 11, 2023Ugur E, de la Porte A, Qin W, Bultmann S, Ivanova A, Drukker M, Mann M, Wierer M, Leonhardt H.

(9) Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cellsCell reportsMarch 28, 2023Li S, Wang CS, Montel-Hagen A, Chen HC, Lopez S, Zhou O, Dai K, Tsai S, Satyadi W, Botero C, et al.

(10) Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5The Journal of biological chemistryMarch 1, 2023Choi EB, Vodnala M, Saini P, Anugula S, Zerbato M, Ho JJ, Wang J, Ho Sui SJ, Yoon J, Roels M, et al.

(11) Comparative study of differentiating human pluripotent stem cells into vascular smooth muscle cells in hydrogel-based culture methodsRegenerative therapyMarch 1, 2023Liu Q, Liu Z, Gu H, Ge Y, Wu X, Zuo F, Du Q, Lei Y, Wang Z, Lin H.

(12) Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocyteseLifeFebruary 22, 2023Dicks AR, Maksaev GI, Harissa Z, Savadipour A, Tang R, Steward N, Liedtke W, Nichols CG, Wu CL, Guilak F.

(13) Programming multicellular assembly with synthetic cell adhesion moleculesNatureFebruary 1, 2023Stevens AJ, Harris AR, Gerdts J, Kim KH, Trentesaux C, Ramirez JT, McKeithan WL, Fattahi F, Klein OD, Fletcher DA, et al.

(14) T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formationeLifeJanuary 31, 2023Landshammer A, Bolondi A, Kretzmer H, Much C, Buschow R, Rose A, Wu HJ, Mackowiak SD, Braendl B, Giesselmann P, et al.

(15) Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiationNature communicationsJanuary 25, 2023Madrigal P, Deng S, Feng Y, Militi S, Goh KJ, Nibhani R, Grandy R, Osnato A, Ortmann D, Brown S, et al.

(16) An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtypeGenome biologyJanuary 23, 2023Shah PP, Keough KC, Gjoni K, Santini GT, Abdill RJ, Wickramasinghe NM, Dundes CE, Karnay A, Chen A, Salomon REA, et al.

(17) In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinomaNature communicationsJanuary 17, 2023Taniguchi S, Matsui T, Kimura K, Funaki S, Miyamoto Y, Uchida Y, Sudo T, Kikuta J, Hara T, Motooka D, et al.

(18) Endothelial progenitor cells derived from embryonic stem cells prevent alveolar simplification in a murine model of bronchopulmonary dysplasiaFrontiers in cell and developmental biologyJanuary 1, 2023Kolesnichenko OA, Flood HM, Zhang Y, Ustiyan V, Cuervo Jimenez HK, Kalin TV, Kalinichenko VV.-2i media base (2i media without the inhibitors and LIF) supplemented with Activin A (R&D Systems, 338-AC-010/CF), BMP4 (R&D Systems, 5020-BP-010/CF), and EGF (Gold Biotechnology, 1350-04-500). After 24 h, the medium

(19) Activin B and Activin C Have Opposing Effects on Prostate Cancer Progression and Cell GrowthCancersDecember 27, 2022Reader KL, John-McHaffie S, Zellhuber-McMillan S, Jowett T, Mottershead DG, Cunliffe HE, Gold EJ.

(20) Activin A Reduces Porcine Granulosa Cells Apoptosis via ERβ-Dependent ROS ModulationVeterinary sciencesDecember 18, 2022Chen F, Zhu X.

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Activin A Protein

Activin A Protein

Activin A Protein

Activin A Protein

Activin A Protein

Recombinant Human/Mouse/Rat Activin A Protein, CF from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

Citations (521)

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Recombinant Human/Mouse/Rat Activin A Protein, CF from R&D Systems, a Bio-Techne Brand

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