IGF-I/IGF-1 Protein 291-G1-200 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIGF-I/IGF-1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $257.00Supplier Page View Company Product Page
Catalog Number291-G1-200
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size200 ug (also 1 mg)
Molecule NameIGF-I/IGF-1
NCBI Full Gene Nameinsulin like growth factor 1
NCBI Gene AliasesIGF, IGFI, IGF-I, MGF
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human IGF-I/IGF-1 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 200 ug (also 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Sphingolipid-neutralizing molecular therapy reduces psychosine cytotoxicity in Krabbe diseaseiScienceMarch 20, 2026Salma Begum, Shin-Chang Hsueh, Ezra M.Y. Cheria, Jayar Espejo, Ping Zhang, Armand Collin, Edgar Kappauf, Murielle Mardenli, Michael H. Gelb, Chang-Chun Ling, et al.201536",Cat#221-AA-050 "Recombinant human IGF-I, CF","R&D Systems; Method described in Douvratas et al., 201536",Cat# 291-G1-200 Recombinant human HGF,"R&D Systems; Method described in Douvratas et al., 201536",Cat# 294-HG-025 Neurotrophin

(2) Generation and characterization of human induced pluripotent stem cells from neuropathologically confirmed multiple system atrophy patient-derived fibroblastsFrontiers in ImmunologyFebruary 23, 2026Mireia Alemany-Ribes, Alexandra Pérez-Soriano, Almudena Santos, Jacqueline Severino, Adrià Dangla-Valls, Martín Gigirey-Suárez, Dory Cohen, Mario Ezquerra, Ruben Fernandez-Santiago, Manel Fernandez, et al.factor AA (PDGFAA),R&D systems,Cat#221-AA-050 Insulin-like growth factor 1 (IGF-I),R&D systems,Cat#291-G1-200 Hepatocyte growth factor (HGF),R&D systems,Cat#294-HG-025/CF Neurotrophin 3 (NT3),Sigma-Aldrich,Cat#GF308 "3,3,5-Triiodo-L-thyronine

(3) Blocking RAN translation without altering repeat RNAs rescues C9ORF72 -related ALS and FTD phenotypesScienceFebruary 5, 2026Xin Jiang, Laure Schaeffer, Divya Patni, Tommaso Russo, Chao-Zong Lee, Corey Aguilar, Christine Marques, Karen Jansen-West, Marian Hruska-Plochan, Ananya Ray-Soni, et al.(Life Technologies, PHC7074), 1 ng/ml GDNF (Stemcell Technologies, 78139.1), 1 ng/ml IGF-1 (R&D Systems, 291-G1-200), 1 ng/ml CNTF (R&D Systems, PHC7015), 10 nM retinoic acid (Sigma-Aldrich, R2625), 2 μg/ml doxycycline

(4) Dysregulated Expression of Inflammasome and Extracellular Matrix Genes in C9orf72 -ALS/FTD MicrogliaASN NeuroDecember 31, 2025Louise Thiry, Nisha S. Pulimood, Ye Man Tang, Stefano StifaniE (MilliporeSigma; Cat. No. 565790), insulin-like growth factor 1 (10 ng/mL; R&D Systems; Cat. No. 291-G1-200), brain-derived neurotrophic factor (10 ng/mL; Thermo-Fisher Scientific; Cat. No. PHC7074) and ciliary

(5) A Human Model of Oligodendrocyte Development Shows MCL-1 Influences Oligodendrocyte MorphogenesisGliaDecember 19, 2025Melanie Gil, Marina R. Hanna, Vivian GamaA supplement, 10 ng/mL PDGF‐AA Protein (R&D Systems, 221‐AA), 10 ng/mL IGF‐I Protein (R&D Systems, 291‐G1‐200), 5 ng/mL HGF Protein (PeproTech, 315‐23), 10 ng/mL NT‐3 Protein (PeproTech, 450‐03), 60 ng/mL 3,3′,5‐Triiodo‐l‐thyronine

(6) Protocol for 3D direct reprogramming of human glia into dopaminergic neurons with gene expression and immunocytochemistry validationSTAR ProtocolsDecember 1, 2025Jessica Giacomoni, Kerstin Laurin, Malin Parmar, Mette HabekostP4957 Recombinant Human GDNF Protein,R&D Systems,Cat# 212-GD-010 Recombinant Human IGF-I Protein,R&D Systems,Cat# 291-G1-200 Recombinant Human Noggin Protein,Miltenyi Biotec,Cat# 130-103-456 Recombinant Human NT-3 Protein,R&D Systems

(7) CHD7 regulates cardiac neural crest cell differentiation through SOX5-mediated self-activationiScienceNovember 21, 2025Shun Yan, Andrey Bombin, Weiwei Liu, Yeimy Gonzalez-Giraldo, Feng Zhou, Huidong Shi, Qin Wang, Kai JiaoFactor-Basic, human",Millipore Sigma,Cat#F0291 Insulin-like growth factor 1 (IGF-1),R&D Systems,Cat# 291-G1-200 Collagen I,Corning,Cat#CLS354236-1 EA "Griffonia Simplicifolia Lectin I (GSL I) Isolectin B4, DyLight®

(8) Transient gene melting governs the timing of oligodendrocyte maturationCellOctober 30, 2025Kevin C. Allan, Jesse J. Zhan, Andrew R. Morton, Erin F. Cohn, Marissa A. Scavuzzo, Anushka Nikhil, Matthew S. Elitt, Benjamin L.L. Clayton, Lucille R. Hu, H. Elizabeth Shick, et al.Aldrich,Cat#P3655-50MG Laminin,Sigma Aldrich,Cat#L2020-1MG Noggin,R&D Systems,Cat#3344NG050 IGF-1,R&D Systems,Cat#291G1200 cyclic AMP,Sigma Aldrich,Cat#D0260-100MG NT3,Thermo Fisher Scientific,Cat#267N3025 T3 (Thyroid hormone),Sigma

(9) Mu opioid receptor activation in microglia enhances HIV-1 infection and HIV-infection-induced inflammatory responsesFront ImmunolOctober 6, 2025Chelsey Skeete, Gabriel Sgambettera, Aldana D. Gojanovich, Xianbao He, Daniel Bryant, Mengwei Yang, Shreya Banerjee, Andrés A. Quiñones-Molina, Hisashi Akiyama, Gustavo Mostoslavsky, et al.IL-11 (Peprotech, catalog #200-11), 25 ng/ml insulin like growth factor-1 (IFG1) (R&D Systems, catalog #291-G1-200) and 20 ng/ml sonic hedgehog recombinant protein (SHH) (Peprotech, catalog #100-45). Cells were switched

(10) Generation of human induced pluripotent stem cell (iPSC) lines from two patients with BAG3 P209L myofibrillar myopathy-6Stem cell researchAugust 1, 2025Filippi K, Wiemann M, Rupp S, Peitz M, Fleischmann BK, Hesse M.

(11) Flow-sensitive HEG1 controls eNOS activity to prevent endothelial dysfunction, hypertension, and atherosclerosisbioRxiv : the preprint server for biologyJune 27, 2025Clark MD, Kim Y, Romero CA, Kang DW, Baek KI, Song EJ, Kellum CE, Bowman-Kirigin JA, Park C, Kapoor V, et al.

(12) Systemic IGF-1 administration prevents traumatic brain injury induced gut permeability, dysmorphia, dysbiosis, and the increased number of immature dentate granule cellsActa neuropathologica communicationsMay 3, 2025Venkatasamy L, Iannucci J, Pereverzev A, Hoar J, Huber E, Ifegbo A, Dominy R, El-Hakim Y, Mani KK, Dabney A, et al.

(13) Construction organoid model of ovarian endometriosis and the function of estrogen and progesterone in the modelScientific reportsFebruary 24, 2025Zhang R, Yang Y, Li R, Ma Y, Ma S, Chen X, Li B, Li B, Qi X, Ha C.

(14) MCL-1 regulates cellular transitions during oligodendrocyte developmentbioRxivDecember 23, 2024Melanie Gil, Marina R Hanna, Vivian GamaA supplement, 10 ng/ml PDGF-AA Protein (R&D Systems, 221-AA), 10 ng/ml IGF-I Protein (R&D Systems, 291-G1–200), 5 ng/ml HGF Protein (PeproTech, 315–23), 10 ng/ml NT-3 Protein (PeproTech, 450–03), 60 ng/ml 3,3′,5-Triiodo-L-thyronine

(15) Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves' Orbitopathy in Orbital FibroblastsInvestigative ophthalmology & visual scienceNovember 4, 2024Park SH, Choi SH, Park HY, Ko J, Yoon JS.

(16) p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulationNature communicationsSeptember 6, 2024Campbell CA, Calderon R, Pavani G, Cheng X, Barakat R, Snella E, Liu F, Peng X, Essner JJ, Dorman KS, et al.

(17) Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cellsCell reportsAugust 27, 2024Kent GM, Atkins MH, Lung B, Nikitina A, Fernandes IM, Kwan JJ, Andrews TS, MacParland SA, Keller GM, Gage BK.

(18) Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cellsiScienceJuly 19, 2024Mozin E, Massouridès E, Mournetas V, Lièvre C, Bourdon A, Jackson DL, Packer JS, Seong J, Trapnell C, Le Guiner C, et al.130-103-925 Recombinant Human FGF2,R&D Systems,Cat# 233-FB-010 Recombinant Human IGF-1,R&D Systems,Cat# 291-G1-200 Recombinant Human HGF,R&D Systems,Cat# 294-HG-005 KnockOut™ serum replacement,Thermo Fisher,Cat# 10828010 "Collagenase,

(19) Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitorHeliyonJune 15, 2024Majlessipour F, Zhu G, Baca N, Kumbaji M, Hwa V, Danielpour M.

(20) Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivoNatureMay 1, 2024Lorenzo-Martín LF, Hübscher T, Bowler AD, Broguiere N, Langer J, Tillard L, Nikolaev M, Radtke F, Lutolf MP.

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IGF-I/IGF-1 Protein

IGF-I/IGF-1 Protein

IGF-I/IGF-1 Protein

IGF-I/IGF-1 Protein

IGF-I/IGF-1 Protein

IGF-I/IGF-1 Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (265)

Reviews

IGF-I/IGF-1 Protein from R&D Systems, a Bio-Techne Brand

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