Fig 1: MD simulation of XIAP in complex with Peptide-5. (A) The backbone RMSD of Peptide-5. (B) The backbone RMSD of the complex of XIAP-Peptide-5. (C) RMSF values of XIAP residues in the complex of XIAP-Peptide-5. (D) Rg of XIAP in the complex of XIAP-Peptide-5. (E) The secondary structures analysis of XIAP in the complex of XIAP-Peptide-5.
Fig 2: The binding modes of Peptides 1–5 within the XIAP binding pocket are shown as follows: (A, B) Peptide-5 is shown in purple; (C, D) Peptide-2 is shown in orange; (E, F) Peptide-3 is shown in pink; (G, H) Peptide-4 is shown in yellow; (I, J) Peptide-5 is shown in green. Active site residues are shown as cyan sticks. Hydrogen bonds are represented in black dashed lines.
Supplier Page from Abcam for Recombinant human XIAP protein (DDDDK tag N-Terminus)