IL-10 Protein 417-ML-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-10 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $292.00Supplier Page View Company Product Page
Catalog Number417-ML-005
SpeciesMouse
Molecule NameIL-10
Source/Expression SystemE. coli-derived Recombinant Mouse IL-10 Protein
Size5 ug (also 25 ug, 100 ug, 250 ug)
NCBI Full Gene Nameinterleukin 10
NCBI Gene AliasesIL10A, GVHDS, TGIF, IL-10, Il-10, CSIF, If2a
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 5 ug (also 25 ug, 100 ug, 250 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Allogeneic MHC-mismatched microglia-like cell replacement as a therapeutic approach for multiple sclerosisJournal of NeuroinflammationJanuary 8, 2026Irene Benito-Cuesta, Jin-Hong Min, Yuxi Guo, Giulia Adriana Virgilio, Valerie Suerth, Stefan Bencina, Paula Trigo-Alonso, Keying Zhu, Shin-Yu Kung, Majid Pahlevan Kakhki, et al.systems, 485-ML-100) to promote a proinflammatory phenotype (M1), or (ii) 20ng/ml IL-10 (R&D systems, 417-ML-005), 20ng/ml IL-4 (R&D systems, 404-ML-010) and 20ng/ml TGF-b 1 (R&D systems, 7666-MB-005) to promote an

(2) Inhalable SPRAY nanoparticles by modular peptide assemblies reverse alveolar inflammation in lethal Gram-negative bacteria infectionScience advancesSeptember 13, 2024Chen D, Zhou Z, Kong N, Xu T, Liang J, Xu P, Yao B, Zhang Y, Sun Y, Li Y, et al.

(3) Tregs delivered post-myocardial infarction adopt an injury-specific phenotype promoting cardiac repair via macrophages in miceNature communicationsAugust 1, 2024Alshoubaki YK, Nayer B, Lu YZ, Salimova E, Lau SN, Tan JL, Amann-Zalcenstein D, Hickey PF, Del Monte-Nieto G, Vasanthakumar A, et al.

(4) Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetesCell reportsJanuary 23, 2024Hou Y, Wei D, Zhang Z, Lei T, Li S, Bao J, Guo H, Tan L, Xie X, Zhuang Y, et al.

(5) Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesiclesMolecular & Cellular ProteomicsNovember 11, 2023Juliet V. Santiago, Aditya Natu, Christina C. Ramelow, Sruti Rayaprolu, Hailian Xiao, Vishnu Kumar, Prateek Kumar, Nicholas T. Seyfried, Srikant Rangaraju(FBS),Gibco,26140-079 Lipopolysaccharide (LPS),Sigma-Aldrich,"L4391, 1 mg" Recombinant mouse IL-10 protein,R&D Systems,"417-ML-005, 5 ug" Recombinant mouse TGF-beta 1 protein,R&D Systems,"7666-MB-005, 5 ug" 0.05% Trypsin-EDTA,Gibco,253000054 Reagent

(6) Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine releaseNature communicationsOctober 9, 2023Adrian M, Weber M, Tsai MC, Glock C, Kahn OI, Phu L, Cheung TK, Meilandt WJ, Rose CM, Hoogenraad CC.

(7) Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesiclesbioRxiv : the preprint server for biologyJuly 29, 2023Santiago JV, Natu A, Ramelow CC, Rayaprolu S, Xiao H, Kumar V, Seyfried NT, Rangaraju S.(FBS),Gibco,26140-079 Lipopolysaccharide (LPS),Sigma-Aldrich,"L4391, 1 mg" Recombinant Mouse IL-10 Protein,R&D Systems,"417-ML-005, 5 ug" Recombinant Mouse TGF-beta 1 Protein,R&D Systems,"7666-MB-005, 5 ug" 0.05% Trypsin-EDTA,Gibco,253000054 Reagent

(8) CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsisCell reportsMarch 28, 2023Yeung ST, Ovando LJ, Russo AJ, Rathinam VA, Khanna KM.

(9) CD4⁺ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survivalCell reportsMarch 29, 2022Yogev N, Bedke T, Kobayashi Y, Brockmann L, Lukas D, Regen T, Croxford AL, Nikolav A, Hövelmeyer N, von Stebut E, et al.

(10) Protocol for in vitro analysis of pro-inflammatory and metabolic functions of cultured primary murine astrocytesSTAR protocolsMarch 18, 2022Gutiérrez-Vázquez C, Quintana FJ.,R&D Systems,#421-ML-025/CF Complement Component C1q Native Protein,MyBioSource,#MBS143105 recombinant mouse IL-10,R&D Systems,#417-ML-005 recombinant GM-CSF,PeproTech,#315-03 "XF DMEM medium, pH 7.4",Agilent Technologies,103575-100 XF

(11) Lactobacillus paracasei KW3110 Prevents Inflammatory-Stress-Induced Mitochondrial Dysfunction in Mouse MacrophagesInternational journal of molecular sciencesJanuary 27, 2022Yamazaki T, Yamada S, Ohshio K, Sugamata M, Morita Y.

(12) Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA₅-Dependent SignalingCellular and molecular gastroenterology and hepatologyJanuary 1, 2022Liang Z, He P, Han Y, Yun CC.

(13) Interleukin 10 Attenuates Angiotensin II-Induced Aortic Remodelling by Inhibiting Oxidative Stress-Induced Activation of the Vascular p38 and NF-κB PathwaysOxidative medicine and cellular longevityJanuary 1, 2022Qiu M, Shu H, Li L, Shen Y, Tian Y, Ji Y, Sun W, Lu Y, Kong X.2002) were obtained from ALZET Corporation (Cupertino, CA, USA). Recombinant mouse IL-10 (cat. no. 417-ML-005) was purchased from R&D Systems, Inc. (MN, USA). Ten percent neutral formalin fix solution (cat. no.

(14) Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary AnalysesBioMed research internationalJanuary 1, 2022Shaik AP, Shaik AS, Abudawood M, Al Faraj A.

(15) Differential Cytokine-Induced Responses of Polarized MicrogliaBrain sciencesNovember 10, 2021Chauhan P, Sheng WS, Hu S, Prasad S, Lokensgard JR.

(16) The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neuronsJournal of neuroinflammationNovember 8, 2021Shi Y, Li S, Zhang H, Zhu J, Che T, Yan B, Li J, Liu C.

(17) Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cellsCell reportsJuly 6, 2021Dupraz L, Magniez A, Rolhion N, Richard ML, Da Costa G, Touch S, Mayeur C, Planchais J, Agus A, Danne C, et al.

(18) Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophagesNature communicationsMarch 5, 2021Dowling JK, Afzal R, Gearing LJ, Cervantes-Silva MP, Annett S, Davis GM, De Santi C, Assmann N, Dettmer K, Gough DJ, et al.

(19) Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarizationCarbohydrate polymersFebruary 15, 2021Rangasami VK, Samanta S, Parihar VS, Asawa K, Zhu K, Varghese OP, Teramura Y, Nilsson B, Hilborn J, Harris RA, et al.

(20) Gut-licensed IFNγ⁺ NK cells drive LAMP1⁺TRAIL⁺ anti-inflammatory astrocytesNatureFebruary 1, 2021Sanmarco LM, Wheeler MA, Gutiérrez-Vázquez C, Polonio CM, Linnerbauer M, Pinho-Ribeiro FA, Li Z, Giovannoni F, Batterman KV, Scalisi G, et al.(R&D Systems, 401-ML-005), 500 UI ml−1 IFNβ (R&D Systems, 8234-MB-010/CF), 10 ng ml−1 IL-10 (R&D Systems, 417-ML-005), 10 ng ml−1 TGFβ (Miltenyi, 130-095-067), 10 ng ml−1 IL-17 (R&D Systems, 421-ML-025/CF), 200 ng ml−1

Be the First to Write a Review!

Recombinant Mouse IL-10 Protein

IL-10 Protein

IL-10 Protein

IL-10 Protein

IL-10 Protein

IL-10 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (77)

Reviews

IL-10 Protein from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map