PDGF-AA Protein 221-AA-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemPDGF-AA Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $335.00Supplier Page View Company Product Page
Catalog Number221-AA-010
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Size10 ug (also 25 ug, 50 ug, 100 ug, 1000 ug)
Molecule NamePDGF-AA
NCBI Full Gene Nameplatelet derived growth factor subunit A
NCBI Gene AliasesPDGF1, PDGF-A
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human PDGF-AA Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 25 ug, 50 ug, 100 ug, 1000 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1 G93A ALS Mice by Enhancing Microglial Migration and NeuroprotectionAdvanced ScienceJanuary 4, 2026Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, et al.resuspended in Neurobasal medium supplemented 1% N2, 2% B27, and 1% P/S. 10 ng/ml PDGFaa (R & D system, 221‐AA‐010) was added for OPC culture, whereas 40 ng/ml T3 (Sigma, T‐074) was added to induce differentiation into

(2) Long-term tracking of neural and oligodendroglial development in large-scale human cerebral organoids by noninvasive volumetric imagingScientific reportsJanuary 20, 2025Park S, Min CH, Choi E, Choi JS, Park K, Han S, Choi W, Jang HJ, Cho KO, Kim M.

(3) Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisorCell stem cellJune 6, 2024Guo T, Pei F, Zhang M, Yamada T, Feng J, Jing J, Ho TV, Chai Y.

(4) H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programsbioRxiv : the preprint server for biologyNovember 28, 2023Krug B, Hu B, Chen H, Ptack A, Chen X, Gretarsson KH, Deshmukh S, Kabir N, Andrade AF, Jabbour E, et al.

(5) A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cellsStem cell reportsAugust 8, 2023Jovanovic VM, Weber C, Slamecka J, Ryu S, Chu PH, Sen C, Inman J, De Sousa JF, Barnaeva E, Hirst M, et al.

(6) Pervasive environmental chemicals impair oligodendrocyte developmentbioRxiv : the preprint server for biologyFebruary 12, 2023Cohn EF, Clayton BLL, Madhavan M, Yacoub S, Federov Y, Paul-Friedman K, Shafer TJ, Tesar PJ.

(7) Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down SyndromeInternational journal of molecular sciencesFebruary 9, 2023Campbell NB, Patel Y, Moore TL, Medalla M, Zeldich E.

(8) Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammationExperimental & molecular medicineFebruary 1, 2023Ju H, Yun H, Kim Y, Nam YJ, Lee S, Lee J, Jeong SM, Heo J, Kwon H, Cho YS, et al.

(9) Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancerOncology lettersNovember 1, 2022Tobiume M, Mitsuhashi A, Saijo A, Ogino H, Afroj T, Ogawa H, Goto H, Sato S, Abe A, Haji K, et al.CXCL12/SDF-1 (350-NS-010/CF; R&D Systems), CCL2/MCP-1 (279-MC-010; R&D Systems), PDGF-AA, or PDGF-BB (221-AA-010, 220-BB-010; R&D Systems) was used as a chemoattractant. These chemoattractants were added to the well

(10) Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironmentNature communicationsAugust 26, 2022Tang Y, Kwiatkowski DJ, Henske EP.

(11) Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decayNature communicationsAugust 25, 2022Martin S, Allan KC, Pinkard O, Sweet T, Tesar PJ, Coller J.

(12) SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide productionCell reportsMay 3, 2022Zhou X, Liu J, Zheng Y, Zhang Z, Wu Y, Yang W, Liu J, Huang Y, Yi Y, Zhao Z, et al.

(13) PDGFR-β signaling mediates HMGB1 release in mechanically stressed vascular smooth muscle cellsPloS oneJanuary 1, 2022Kim JO, Baek SE, Jeon EY, Choi JM, Jang EJ, Kim CD.

(14) Transplantable human motor networks as a neuron-directed strategy for spinal cord injuryiScienceAugust 20, 2021Olmsted ZT, Stigliano C, Scimemi A, Wolfe T, Cibelli J, Horner PJ, Paluh JL.SBGD1 NGF,R&D Systems,Cat.No.: 256-GF-100 IGF-1,R&D Systems,Cat.No.: 291-G1 PDGF-AA,R&D Systems,Cat.No.: 221-AA-010 Triiodothyronine (T3),Millipore Sigma,Cat.No.: 64245 Insulin,Sigma Aldrich,Cat.No.: 91077C Heparin,Sigma

(15) PDGFRα: Expression and Function during Mitral Valve MorphogenesisJournal of cardiovascular development and diseaseMarch 13, 2021Moore K, Fulmer D, Guo L, Koren N, Glover J, Moore R, Gensemer C, Beck T, Morningstar J, Stairley R, et al.

(16) Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell FunctionCell stem cellFebruary 4, 2021Allan KC, Hu LR, Scavuzzo MA, Morton AR, Gevorgyan AS, Cohn EF, Clayton BLL, Bederman IR, Hung S, Bartels CF, et al.

(17) ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular ResponseCell stem cellFebruary 4, 2021Wang C, Zhang M, Garcia G Jr, Tian E, Cui Q, Chen X, Sun G, Wang J, Arumugaswami V, Shi Y.

(18) Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cellsNature communicationsJanuary 28, 2021Chamling X, Kallman A, Fang W, Berlinicke CA, Mertz JL, Devkota P, Pantoja IEM, Smith MD, Ji Z, Chang C, et al.

(19) Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery modelScientific reportsDecember 1, 2020Yamamoto Y, Mukai A, Ikushima T, Urata Y, Kinoshita S, Hamuro J, Ueno M, Sotozono C.

(20) Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte InteractionsJournal of visualized experiments : JoVENovember 9, 2020Assetta B, Tang C, Bian J, O'Rourke R, Connolly K, Brickler T, Chetty S, Huang YA.Progenitor Freezing Media,STEMCELL Technologies,5838 DMSO,ThermoFisher,D12345 PDGF-AA,R&D Systems,221-AA-010 SAG,Tocris,4366 bFGF,ThermoFisher,PHG 0266 T3 triiodothyronine,MilliporeSigma,T6397 cAMP,MilliporeSigma,A9501 Clemastine,MilliporeSigma,SML0445 Tempo-iOlogo:

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PDGF-AA Protein

PDGF-AA Protein

PDGF-AA Protein

PDGF-AA Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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PDGF-AA Protein from R&D Systems, a Bio-Techne Brand

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