DGCR8 knockout Mouse embryonic stem cells NBA1-19349 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemDGCR8 knockout Mouse embryonic stem cells
CompanyNovus Biologicals, a Bio-Techne Brand
Price $579.00Supplier Page View Company Product Page
Catalog NumberNBA1-19349
Size2 ml
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, In vitro assay, In vivo assay
TargetDGCR8 knockout Mouse embryonic stem cells
Research AreaStem Cell Lines, Stem Cell Markers
SpeciesMouse
Validated Species ReactivityMouse (Ms)
FormatCells are supplied in 2 ml quantities (about 1x10 ^ 6 cells/ml) in Freezing Media (60% DMEM, 20% FBS, 20% DMSO)
Cell Typeembryonic stem cells
Typecells
StorageStore in gas phase of liquid nitrogen

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processesCarcinogenesisMarch 24, 2022Vardapour R, Kehl T, Kneitz S, Ludwig N, Meese E, Lenhof HP, Gessler M.

(2) MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon responseeLifeApril 23, 2019Witteveldt J, Knol LI, Macias S.methods Cells and viruses Dgcr8 knockout (Dgcr8-/-) mouse ESCs were purchased from Novus Biologicals (NBA1-19349) and the parental strain, v6.5 (Dgcr8+/+, also named in the text ESC1) from ThermoFisher (MES1402).

(3) Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cellseLifeJuly 25, 2018Freimer JW, Hu TJ, Blelloch R.Novus Biologicals." Cell line (Mouse),Dgcr8 KO embryonic stem cell,PMID: 17259983; Novus Biologicals,NBA1-19349,Dgcr8 KO mouse embryonic stem cell line previously generated in the Blelloch lab. Also available commercially

(4) DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAsMolecular cellDecember 17, 2015Macias S, Cordiner RA, Gautier P, Plass M, Cáceres JF.LIF, glutamine, and essential aminoacids. Dgcr8−/− mES cells were purchased from Novus Biologicals (NBA1-19349) and the parental strain (v6.5) from Thermo Scientific (MES1402). Dicer−/− and f/f Dicer were kindly

(5) MicroRNAome of porcine conceptuses and trophoblasts: expression profile of micrornas and their potential to regulate genes crucial for establishment of pregnancyBiology of reproductionJanuary 1, 2015Krawczynski K, Najmula J, Bauersachs S, Kaczmarek MM.

(6) RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cellsPLoS geneticsNovember 1, 2013Ciaudo C, Jay F, Okamoto I, Chen CJ, Sarazin A, Servant N, Barillot E, Heard E, Voinnet O.medium. TKO mESCs were described in ref. [27]. Dgcr8_KO mESCs were purchased from Novus Biologicals (NBA1-19349). New CreERT2-Dcr Flx/Flx mESCs were isolated from the cross of floxed Dcr Flx/Flx mice [22], [57] and

(7) MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cellsStem cell researchNovember 1, 2013Jiang K, Ren C, Nair VD.

(8) The Microprocessor controls the activity of mammalian retrotransposonsNature structural & molecular biologyOctober 1, 2013Heras SR, Macias S, Plass M, Fernandez N, Cano D, Eyras E, Garcia-Perez JL, Cáceres JF.(v/v) fetal bovine serum (GIBCO-Invitrogen). Dgcr8−/−mES cells were purchased from Novus Biologicals (NBA1-19349) and the parental strain (v6.5) from Thermo Scientific (MES1402). Dicer−/− and f/f Dicer were kindly

(9) C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosisMolecular and cellular neurosciencesSeptember 1, 2013Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA.

(10) DGCR8 HITS-CLIP reveals novel functions for the MicroprocessorNature structural & molecular biologyAugust 1, 2012Macias S, Plass M, Stajuda A, Michlewski G, Eyras E, Cáceres JF.

(11) Biogenesis of mammalian microRNAs by a non-canonical processing pathwayNucleic acids researchMay 1, 2012Havens MA, Reich AA, Duelli DM, Hastings ML.

(12) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewalNature geneticsMarch 1, 2007Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R.

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DGCR8 knockout Mouse embryonic stem cells

DGCR8 knockout Mouse embryonic stem cells

DGCR8 knockout Mouse embryonic stem cells

DGCR8 knockout Mouse embryonic stem cells

DGCR8 knockout Mouse embryonic stem cells

DGCR8 knockout Mouse embryonic stem cells from Novus Biologicals, a Bio-Techne Brand

Novus Biologicals, a Bio-Techne Brand

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DGCR8 knockout Mouse embryonic stem cells from Novus Biologicals, a Bio-Techne Brand

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