SOC Medium

SOC Medium, shorthand for Super Optimal broth with Catabolite repression, is a nutritionally rich bacterial culture medium. The recipe is differs slightly with LB broth, containing 20 g/L tryptone, 5 g/L yeast extract, and 0.5 g/L sodium chloride. A defining ingredient is 20 mM glucose, which must be added separately after the media has cooled. SOC medium is typically used to grow competent cells to maximize the efficiency of bacterial plasmid transformations. 

SOC Medium

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New England Biolabs
SOC Outgrowth Medium
  • Description:
    Add SOC to freshly transformed E.coli cells and incubate for up to 1 hour before plating on selective media.
  • Quantity:
    100 ml
  • Format:
    Liquid
  • Media Type:
    SOC Medium
Citations:
(49)
United States Biological
SOC Broth (Powder)
  • Quantity:
    500g
  • Media Type:
    SOC Medium
Citations:
(1)
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