The Biocompare Microscopes and Cell Imaging Systems search tool enables users to compare different instrument specifications, features, and applications to best serve the unique imaging needs of biological researchers. Contemporary microscopes are stand-alone optical devices that enable the necessary magnification needed to visualize processes at the tissue and cellular levels. Thanks to advances in optical technologies, researchers today can enjoy many choices in instruments. Microscopes and imaging systems can be categorized by their general build (such as upright, inverted, or digital systems) or primary function (stereo/zoom, electron, confocal, super-resolution, in vivo imaging, or slide scanning). Another important consideration is the imaging application, as many instrument models can offer multiple capabilities, such as phase contrast, polarization, luminescence, multi-channel fluorescence, darkfield, live cell imaging, 3D imaging, time-lapse, and more. When choosing an imaging instrument, also consider useful features such as automation compatibility, customization options, remote access, and control chambers. Use the filters on the left to simplify your search and click on the products below for more information.
Confocal laser scanning microscopy (CLSM or LSCM) obtains high-resolution optical images by acquiring images point-by-point and reconstructing them with a computer, allowing three-dimensional reconstructions of topologically complex objects. These microscopes, found in biomedical clinical and research laboratories, are used in sensitivity demanding applications. There are two main subcategories- single point, often used in tissue slice imaging, and array scanning- often used for live cell imaging. The major optical microscopy vendors—Olympus, Nikon Instruments, Leica Microsystems and Carl Zeiss MicroImaging—offer confocal microscopes. When choosing a system, consider the applications such as live-cell imaging or fixed-tissue sections, FRET, multiphoton microscopy or super-resolution imaging. Expanding into different types of imaging requires upgradability. Also important in system selection is ease of use, availability of maintenance contracts and access to technical support.