SIGMAR1 ELISA kits are immunoassay tools for the measurement of the protein sigma non-opioid intracellular receptor 1, which is encoded by the SIGMAR1 gene in humans. Functionally, this protein is reported to function in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. The canonical protein structure is reported to have an amino acid length of 223 residues, a mass of 25.1 kDa, and is a member of the ERG2 protein family. It is known to be localized in the nucleus, cytoplasmic vesicles, ER, and cell membrane and is reported to be widely expressed with higher expression in liver, colon, prostate, placenta, small intestine, heart and pancreas. As many as 5 protein isoforms have been reported. The SIGMAR1 gene has been associated with the disease, Amyotrophic lateral sclerosis. Other alias names for this target include DSMA2, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, and ALS16.
Some SIGMAR1 ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.