The Gremlin ELISA kits listed below utilize specific antibodies for the plate-based assay of Gremlin in various samples. Gremlin is another term for the GREM1 gene, which encodes the protein, gremlin 1, DAN family BMP antagonist in humans. It has been reported that Gremlin plays a role in organ morphogenesis and the apoptotic pathway, among other functions. Structurally, the GREM1 protein is 184 amino acid residues in length and 20.7 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is known to be a secreted protein. In terms of tissue specificity, it is reported to be highly expressed in small intestine, fetal brain and colon. This protein is known to be glycosylated. Other names for this target antigen include C15DUPq, CKTSF1B1, and CRAC1.
The detection range for different Gremlin ELISA kits can vary, with some assays measuring target concentrations as low as 93.8 pg/mL and as high as 100 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.