IRF8 ELISA kits are immunoassay tools for the measurement of the protein interferon regulatory factor 8, which is encoded by the IRF8 gene in humans. Functionally, this protein is reported to be a transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). The canonical protein structure is reported to have an amino acid length of 426 residues, a mass of 48.4 kDa, and is a member of the IRF protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be highly expressed in the lymphoid tissues. The protein has been noted to be post-translationally ubiquitinated and sumoylated. The IRF8 gene has been associated with the disease, Immunodeficiency. Other alias names for this target include ICSBP, ICSBP1, IMD32A, IMD32B, interferon consensus sequence binding protein 1, and H-ICSBP.
The detection range for different IRF8 ELISA kits can vary, with some assays measuring target concentrations as low as 5 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.