APEX1 ELISA kits are immunoassay tools for the measurement of the protein apurinic/apyrimidinic endodeoxyribonuclease 1, which is encoded by the APEX1 gene in humans. Functionally, this protein is reported to be a multifunctional protein that plays a central role in the cellular response to oxidative stress. The canonical protein structure is reported to have an amino acid length of 318 residues, a mass of 35.6 kDa, and is a member of the DNA repair enzymes AP/ExoA protein family. It is known to be localized in the nucleus, ER, and cytoplasm. The protein has been noted to be post-translationally ubiquitinated, acetylated, cleaved and phosphorylated. The APEX1 gene has been associated with the disease, . Other alias names for this target include APE1, APEN, APEX, APX, HAP1, REF1, DNA-(apurinic or apyrimidinic site) endonuclease, and APE.
The detection range for different APEX1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.