The following Itchy E3 Ubiquitin Protein Ligase ELISA kits are useful research tools for the measurement of itchy E3 ubiquitin protein ligase in biological samples. In humans this protein is encoded by the ITCH gene. This protein is known to act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. The canonical protein structure is reported to have an amino acid sequence of 903 residues and a mass of 102.8 kDa. Its subcellular location is known to be in the cell membrane, nucleus, and cytoplasm. In addition, it is widely expressed across many tissue types. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Autoimmune disease. This protein may also be known as HECT-type E3 ubiquitin transferase Itchy homolog, NFE2-associated polypeptide 1, atrophin-1 interacting protein 4, itchy E3 ubiquitin protein ligase homolog, and E3 ubiquitin-protein ligase Itchy homolog.
Some Itchy E3 Ubiquitin Protein Ligase ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.