Neopterin ELISA kits are assays designed to detect neopterin, a pyrazinopyridine derivative of guanosine triphosphate (GTP). This small molecule is produced by macrophages, dendritic cells and lymphocytes. It acts as a marker of immune system activation. Production of neopterin is stimulated by IFN-γ released from Th1 cells and natural killer cells. Elevated levels of neopterin in cerebrospinal fluid is seen in conditions of metabolic stress, microbial infection, demyelination, allograft rejection, autoimmune and neurological diseases. Visit the supplier page for more information about detection range and reactivity.