The following hydroxysteroid 11-beta dehydrogenase 2 ELISA kits are useful research tools for the measurement of hydroxysteroid 11-beta dehydrogenase 2 in biological samples. In humans this protein is encoded by the HSD11B2 gene. This protein is known to catalyze the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+). The canonical protein structure is reported to have an amino acid length of 405 residues, a mass of 44.1 kDa, and is a member of the Short-chain dehydrogenases/reductases (SDR) protein family. Its subcellular location is known to be in the ER. In addition, it is reported to be expressed in kidney, placenta, pancreas, prostate, ovary, small intestine and colon, and in lower levels in the spleen and testis. The gene encoding this protein has been associated with the disease, Apparent mineralocorticoid excess. This protein may also be known as AME1, HSD11K, HSD2, SDR9C3, 11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-HSD type II, and AME.
The detection range for different hydroxysteroid 11-beta dehydrogenase 2 ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.