The following DNA Topoisomerase I ELISA kits are useful research tools for the measurement of DNA topoisomerase I in biological samples. In humans this protein is encoded by the TOP1 gene. This protein has been described to function in chromatin remodeling and DNA replication. The canonical protein structure is reported to have an amino acid length of 765 residues, a mass of 90.7 kDa, and is a member of the Type IB topoisomerase protein family. Its subcellular location is known to be in the nucleus. In certain instances, it is also post-translationally sumoylated and phosphorylated. This protein may also be known as DNA topoisomerase 1, Scl-70 antigen, topoisomerase (DNA) I, type I DNA topoisomerase, and TOPI.
The detection range for different DNA Topoisomerase I ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.