KMT2A ELISA kits are immunoassay tools for the measurement of the protein lysine methyltransferase 2A, which is encoded by the KMT2A gene in humans. Functionally, this protein is a known histone methyltransferase that plays an essential role in early development and hematopoiesis. The canonical protein structure is reported to have an amino acid length of 3969 residues, a mass of 431.8 kDa, and is a member of the Histone-lysine methyltransferase protein family. It is known to be localized in the nucleus. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally methylated, cleaved and phosphorylated. The KMT2A gene has been associated with the disease, Wiedemann-Steiner syndrome. Other alias names for this target include ALL1, CXXC7, GAS7, HRX, HTRX, HTRX1, MLL, and ALL-1.
Some KMT2A ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.