The following methylmalonyl-CoA mutase ELISA kits are useful research tools for the measurement of methylmalonyl-CoA mutase in biological samples. In humans this protein is encoded by the MMUT gene. This protein is known to catalyze the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. The canonical protein structure is reported to have an amino acid length of 750 residues, a mass of 83.1 kDa, and is a member of the Methylmalonyl-CoA mutase protein family. Its subcellular location is known to be in the mitochondria and cytoplasm. The gene encoding this protein has been associated with the disease, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. This protein may also be known as MUT, methylmalonyl-CoA mutase, mitochondrial, methylmalonyl Coenzyme A mutase, methylmalonyl-CoA isomerase, and MCM.
There are methylmalonyl-CoA mutase ELISA kits that can detect a target at concentrations as low as 20 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.