The following Synuclein, alpha ELISA kits are useful research tools for the measurement of synuclein alpha in biological samples. In humans this protein is encoded by the SNCA gene. This protein is reported to be a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. The canonical protein structure is reported to have an amino acid length of 140 residues, a mass of 14.5 kDa, and is a member of the Synuclein protein family. Its subcellular location is known to be in the nucleus, cytoplasm, and is secreted. In addition, it is reported to be highly expressed in presynaptic terminals in the central nervous system. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated, acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Parkinson disease. This protein may also be known as PARK1, PARK4, PD1, alpha-synuclein, I+/--synuclein, non A-beta component of AD amyloid, synuclein alpha-140, and NACP.
Some Synuclein, alpha ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 30 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.