ARHGEF1 ELISA kits are immunoassay tools for the measurement of the protein Rho guanine nucleotide exchange factor 1, which is encoded by the ARHGEF1 gene in humans. Functionally, this protein is believed to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. The canonical protein structure is reported to have an amino acid sequence of 912 residues and a mass of 102.4 kDa. It is known to be localized in the cytoplasm and is ubiquitously expressed across many tissue types. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The ARHGEF1 gene has been associated with the disease, Immunodeficiency. Other alias names for this target include IMD62, LBCL2, LSC, P115-RHOGEF, SUB1.5, 115 kDa guanine nucleotide exchange factor, 115-kD protein, and GEF1.
The detection range for different ARHGEF1 ELISA kits can vary, with some assays measuring target concentrations as low as 5 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.