The following Nephrocystin 4 ELISA kits are useful research tools for the measurement of nephrocystin 4 in biological samples. In humans this protein is encoded by the NPHP4 gene. This protein is reported to be involved in organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. The canonical protein structure is reported to have an amino acid length of 1426 residues, a mass of 157.6 kDa, and is a member of the NPHP4 protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be expressed in kidney, skeletal muscle, heart and liver, and to a lesser extent in the brain and lung. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Nephronophthisis. This protein may also be known as POC10 centriolar protein homolog and nephroretinin.
The detection range for different Nephrocystin 4 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.